Clinical Trials
Showing trials with last updates posted in 2025.
752
Participants
Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-07-25
Completion:
2026-12-30
Conditions
Depressive Disorder, Major
Interventions
DRUG
No Results Yet
1184
Participants
Early Antiplatelet Administration After Intravenous Thrombolysis for Acute Ischemic Stroke (TREND-IVT)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-11-07
Completion:
2026-03-31
Conditions
Acute Ischemic Stroke
Cerebral Infarction
Interventions
DRUG
OTHER
No Results Yet
498
Participants
A Study of JNJ-64042056 in Participants With Preclinical Alzheimer's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-07-22
Completion:
2031-07-17
Conditions
Preclinical Alzheimer's Disease
Interventions
DRUG
No Results Yet
490
Participants
MACT (Mono Antiplatelet and Colchicine Therapy) Prospective Multicenter Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-08-05
Completion:
2028-12-31
Conditions
Acute Coronary Syndrome
Interventions
DRUG
No Results Yet
28
Participants
Investigation of the Effect of Massage Application on Functional Status and Depression in Postpartum Mothers
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2024-05-10
Completion:
2024-08-30
Conditions
Depression, Post-Partum
Massage
Functional Status
Interventions
OTHER
No Results Yet
125
Participants
Prospective Cohort Study of a Population at Risk of Psychotic Transition
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2024-11-18
Completion:
2024-11-18
Conditions
At-risk Mental States
Interventions
OTHER
No Results Yet
150
Participants
Optimal Pediatric Heart Transplant Immunosuppression With MicroRNAs
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2025-02-06
Completion:
2029-10-01
Conditions
Cardiac Failure
Graft Rejection
No Results Yet
20
Participants
Comparison of the Non-Dominant Hands of Pianists and the Dominant Hands of Individuals Who Do Not Play Instruments
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2024-06-10
Completion:
2024-06-10
Conditions
Hand
Function
Piano Therapy
Interventions
OTHER
No Results Yet
500
Participants
A Phase 3 Study to Evaluate Petosemtamab Plus Pembrolizumab vs Pembrolizumab in First-line Treatment of Head and Neck Cancer (LiGeR - HN1)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-09-25
Completion:
2028-01-31
Conditions
Head and Neck Squamous Cell Carcinoma
Interventions
DRUG
No Results Yet
12
Participants
Transcatheter Arterial Embolization for Elbow and Foot Plantar Pain
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-04-18
Completion:
2025-09-02
Conditions
Elbow Tendinitis
Elbow Tendinopathy
Epicondylitis of the Elbow
Epicondylitis, Lateral
Plantar Fascitis
Embolization
Interventions
DEVICE
No Results Yet
90
Participants
Erdafitinib Monotherapy or in Combination With Cetrelimab in Muscle-invasive Bladder Cancer Patients With Fibroblast Growth Factor Receptor (FGFR ) Gene Alterations
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-03-07
Completion:
2026-07-31
Conditions
Muscle-invasive Bladder Cancer
Interventions
DRUG
No Results Yet
150
Participants
Radiotherapy Patient Education With Virtual Reality
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-12-04
Completion:
2026-12-31
Conditions
Anxiety
Cancer
Interventions
BEHAVIORAL
No Results Yet
200
Participants
Eliminating Breast Surgery for Breast Cancer Patients With Clinical Complete Response to Neoadjuvant Systemic Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-07-25
Completion:
2026-12-30
Conditions
Breast Cancer
Interventions
RADIATION
No Results Yet
35
Participants
Employment Support After Hematopoietic Stem Cell Transplantation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-07-31
Completion:
2027-12-31
Conditions
Hematopoietic Stem Cell Transplantation
Interventions
BEHAVIORAL
No Results Yet
110
Participants
The Effect of Hypnobreastfeeding Education Given to Primiparas
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-10-01
Completion:
2025-02-01
Conditions
Breastfeeding
Self Efficacy
Expectations
Interventions
BEHAVIORAL
No Results Yet
12
Participants
Atezolizumab in Combination With Stereotactic Body Radiation Therapy (SBRT) and Surgery for Relapsed Osteosarcoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2026-01-31
Completion:
2027-06-30
Conditions
Osteosarcoma
Pulmonary Recurrence of Osteosarcoma
Interventions
PROCEDURE
RADIATION
DRUG
No Results Yet
90
Participants
Asleep Fiberoptic vs Direct Laryngoscopy Effect on Hemodynamic Stability Using Opioid Free Anesthesia Induction
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-09-11
Completion:
2026-01-01
Conditions
Analgesics, Opioid
Anesthesia, General
Heart Rate
Blood Pressure
Interventions
DEVICE
No Results Yet
40
Participants
Impact of Rapid Pathogen Detection in ICU Patients With Suspected Pneumonia on Antimicrobial Therapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-06-26
Completion:
2025-11-01
Conditions
Pneumonia
Critically Ill
Interventions
DIAGNOSTIC_TEST
No Results Yet
0
Participants
The Effects of Semaglutide on Body Composition and Performance in Military Personnel
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-08-01
Completion:
2025-03-27
Conditions
Obesity
Interventions
DRUG
No Results Yet
187
Participants
Efficacy of a Mixed Distancial Neuropsychological Rehabilitation Program in Patients With Grade 2 or 3 Diffuse Glioma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-07-05
Completion:
2027-10-15
Conditions
Glioma, Malignant
Interventions
OTHER
No Results Yet
264
Participants
Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-06-25
Completion:
2028-05-19
Conditions
Generalized Myasthenia Gravis
Interventions
OTHER
DRUG
No Results Yet
200
Participants
Impact of Diabetes Mellitus on Retinal Microvasculature in Patients Without Clinical Retinopathy Using Optical Coherence Tomography Angiography
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2024-12-20
Completion:
2025-08-01
Conditions
Diabetic Retinopathy, DR
Interventions
DIAGNOSTIC_TEST
No Results Yet
900
Participants
Understanding Patient Preference on Colorectal Cancer Screening Options-PSU
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2024-09-16
Completion:
2025-12-31
Conditions
Colo-rectal Cancer
Interventions
BEHAVIORAL
No Results Yet
60
Participants
A First in Human Trial Evaluating THB335 in Healthy Participants
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-05-02
Completion:
2024-12-18
Conditions
Healthy
Interventions
DRUG
No Results Yet
150
Participants
Effect of peRiopErative duLoxetIne Administration on Opioid Consumption Following Total kneE Arthroplasty (RELIFE)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-11-01
Completion:
2026-07-01
Conditions
Knee Osteoarthritis
Interventions
DRUG
No Results Yet
141
Participants
M9466 Alone or in Combination in Advanced Solid Tumors (DDriver 501)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-08-07
Completion:
2027-02-22
Conditions
Advanced Solid Tumor
Interventions
DRUG
No Results Yet
30
Participants
Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-07-23
Completion:
2029-05-12
Conditions
Recurrent Glioblastoma, IDH-Wildtype
Recurrent WHO Grade 2 Glioma
Recurrent WHO Grade 3 Glioma
Recurrent WHO Grade 4 Glioma
Interventions
PROCEDURE
OTHER
DRUG
No Results Yet
495
Participants
A Study of LY4170156 in Participants With Selected Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-05-20
Completion:
2027-02-28
Conditions
Ovarian Neoplasms
Endometrial Neoplasms
Uterine Cervical Neoplasms
Carcinoma, Non-Small-Cell Lung
Triple Negative Breast Neoplasms
Pancreatic Neoplasm
Colorectal Neoplasms
Interventions
DRUG
No Results Yet
200
Participants
A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-05-17
Completion:
2027-07-01
Conditions
Cerebral Amyloid Angiopathy
Interventions
DRUG
No Results Yet
695
Participants
Low Birthweight and Preterm Infant Feeding Trial and Supportive Care Package: Implementation Research
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-05-08
Completion:
2026-02-28
Conditions
Low Birthweight
Preterm Birth
Interventions
OTHER
No Results Yet
2000
Participants
Pancreatic Cancer Detection Consortium
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2023-03-15
Completion:
2026-06-18
Conditions
Pancreatic Cancer Stage II
Pancreatic Cancer Stage III
Pancreatic Cancer, Adult
Pancreatic Cancer Non-resectable
Pancreatic Cancer
Pancreatic Carcinoma
Pancreatic Adenocarcinoma
Pancreatic Ductal Adenocarcinoma
Pancreatic Neoplasms
Pancreatic Cancer Stage I
Pancreatic Cancer Stage
Pancreatic Cancer Resectable
Pancreatic Cancer Stage 0
Interventions
DIAGNOSTIC_TEST
No Results Yet
287
Participants
A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-04-22
Completion:
2027-12-27
Conditions
Squamous Cell Carcinoma of Head and Neck
Interventions
BIOLOGICAL
DRUG
No Results Yet
100
Participants
Oral Curcumin for the Treatment of Pain of Thumb Base Joint (CMC) Arthritis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-02-01
Completion:
2026-02-28
Conditions
Arthritis of Carpometacarpal Joint of Left Thumb
Arthritis of Carpometacarpal Joint of Right Thumb
Interventions
DRUG
No Results Yet
200
Participants
Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for AUD
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-08-26
Completion:
2029-05-31
Conditions
Alcohol Use Disorder
Interventions
DRUG
OTHER
BEHAVIORAL
No Results Yet
30
Participants
Validating Innovative Biosensors for Rett Autonomic Symptom Tracking
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2025-03-03
Completion:
2026-06-30
Conditions
Rett Syndrome
No Results Yet
40
Participants
SMosE Safety and Efficacy Evaluation as a Skin Adaptogen
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-10-01
Completion:
2023-11-15
Conditions
Sebum Production
Acne Scars
Skin Barrier to Water Loss
Interventions
OTHER
No Results Yet
23
Participants
Abbreviated MBCT for Depression in Older African American/Black Breast Cancer Survivors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-03-21
Completion:
2026-01-31
Conditions
Breast Cancer
Breast Cancer Female
Breast Cancer Stage I
Breast Cancer Stage II
Breast Cancer Stage III
Mild Depression
Moderate Depression
Interventions
OTHER
No Results Yet
60
Participants
Efficacy of Personnalized Transcranial Direct Current Electrical Stimulation (tDCS) in Drug-resistant Epileptic
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-12-18
Completion:
2026-12-18
Conditions
Epilepsy
Drug Resistant Epilepsy
Interventions
DEVICE
No Results Yet
1070
Participants
Total Underwater Colonoscopy (TUC) for Improved Colorectal Cancer Screening: A Randomized Controlled Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-10-23
Completion:
2026-12-31
Conditions
Colorectal Neoplasia
Screening Colonoscopy
Colorectal Cancer
Colorectal Cancer Screening
Vasovagal Reaction
Interventions
PROCEDURE
No Results Yet
501
Participants
PREVAIL Paclitaxel-coated Balloon in Small Coronary Disease and High-bleeding Risk Patients
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2024-02-26
Completion:
2026-01-30
Conditions
Coronary Artery Disease
Interventions
DEVICE
No Results Yet
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