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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06468176 | RECRUITING | NA
187 Participants

Efficacy of a Mixed Distancial Neuropsychological Rehabilitation Program in Patients With Grade 2 or 3 Diffuse Glioma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-07-05
Completion: 2027-10-15
Conditions
Glioma, Malignant
Interventions
OTHER
No Results Yet
NCT06463587 | RECRUITING | PHASE3
264 Participants

Efficacy and Safety of a New Formulation of Oral Cladribine Compared With Placebo in Participants With Generalized Myasthenia Gravis (MyClad)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-06-25
Completion: 2028-05-19
Conditions
Generalized Myasthenia Gravis
Interventions
OTHER DRUG
No Results Yet
NCT06457295 | COMPLETED
200 Participants

Impact of Diabetes Mellitus on Retinal Microvasculature in Patients Without Clinical Retinopathy Using Optical Coherence Tomography Angiography

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2024-12-20
Completion: 2025-08-01
Conditions
Diabetic Retinopathy, DR
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06444542 | RECRUITING
900 Participants

Understanding Patient Preference on Colorectal Cancer Screening Options-PSU

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2024-09-16
Completion: 2025-12-31
Conditions
Colo-rectal Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT06425861 | COMPLETED | PHASE1
60 Participants

A First in Human Trial Evaluating THB335 in Healthy Participants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-05-02
Completion: 2024-12-18
Conditions
Healthy
Interventions
DRUG
No Results Yet
NCT06423716 | RECRUITING | PHASE4
150 Participants

Effect of peRiopErative duLoxetIne Administration on Opioid Consumption Following Total kneE Arthroplasty (RELIFE)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-11-01
Completion: 2026-07-01
Conditions
Knee Osteoarthritis
Interventions
DRUG
No Results Yet
NCT06421935 | ACTIVE_NOT_RECRUITING | PHASE1
141 Participants

M9466 Alone or in Combination in Advanced Solid Tumors (DDriver 501)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-08-07
Completion: 2027-02-22
Conditions
Advanced Solid Tumor
Interventions
DRUG
No Results Yet
NCT06410248 | ACTIVE_NOT_RECRUITING | PHASE1
30 Participants

Triapine in Combination With Temozolomide for the Treatment of Patients With Recurrent Glioblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-07-23
Completion: 2029-05-12
Conditions
Recurrent Glioblastoma, IDH-Wildtype Recurrent WHO Grade 2 Glioma Recurrent WHO Grade 3 Glioma Recurrent WHO Grade 4 Glioma
Interventions
PROCEDURE OTHER DRUG
No Results Yet
NCT06393712 | RECRUITING | PHASE2
200 Participants

A Phase 2 Trial of ALN-APP in Patients With Cerebral Amyloid Angiopathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-05-17
Completion: 2027-07-01
Conditions
Cerebral Amyloid Angiopathy
Interventions
DRUG
No Results Yet
NCT06390943 | RECRUITING | NA
695 Participants

Low Birthweight and Preterm Infant Feeding Trial and Supportive Care Package: Implementation Research

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-05-08
Completion: 2026-02-28
Conditions
Low Birthweight Preterm Birth
Interventions
OTHER
No Results Yet
NCT06388967 | RECRUITING
2000 Participants

Pancreatic Cancer Detection Consortium

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2023-03-15
Completion: 2026-06-18
Conditions
Pancreatic Cancer Stage II Pancreatic Cancer Stage III Pancreatic Cancer, Adult Pancreatic Cancer Non-resectable Pancreatic Cancer Pancreatic Carcinoma Pancreatic Adenocarcinoma Pancreatic Ductal Adenocarcinoma Pancreatic Neoplasms Pancreatic Cancer Stage I Pancreatic Cancer Stage Pancreatic Cancer Resectable Pancreatic Cancer Stage 0
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06385080 | RECRUITING | PHASE1/PHASE2
287 Participants

A Study of Amivantamab Alone or in Addition to Other Treatment Agents in Participants With Head and Neck Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-04-22
Completion: 2027-12-27
Conditions
Squamous Cell Carcinoma of Head and Neck
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06359665 | ENROLLING_BY_INVITATION | PHASE1
100 Participants

Oral Curcumin for the Treatment of Pain of Thumb Base Joint (CMC) Arthritis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-02-01
Completion: 2026-02-28
Conditions
Arthritis of Carpometacarpal Joint of Left Thumb Arthritis of Carpometacarpal Joint of Right Thumb
Interventions
DRUG
No Results Yet
NCT06349083 | RECRUITING | PHASE2
200 Participants

Neurobehavioral Mechanisms of Psilocybin-assisted Treatment for AUD

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-08-26
Completion: 2029-05-31
Conditions
Alcohol Use Disorder
Interventions
DRUG OTHER BEHAVIORAL
No Results Yet
NCT06338267 | RECRUITING
30 Participants

Validating Innovative Biosensors for Rett Autonomic Symptom Tracking

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2025-03-03
Completion: 2026-06-30
Conditions
Rett Syndrome
No Results Yet
NCT06338046 | COMPLETED | NA
40 Participants

SMosE Safety and Efficacy Evaluation as a Skin Adaptogen

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-10-01
Completion: 2023-11-15
Conditions
Sebum Production Acne Scars Skin Barrier to Water Loss
Interventions
OTHER
No Results Yet
NCT06336538 | ACTIVE_NOT_RECRUITING | NA
23 Participants

Abbreviated MBCT for Depression in Older African American/Black Breast Cancer Survivors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-03-21
Completion: 2026-01-31
Conditions
Breast Cancer Breast Cancer Female Breast Cancer Stage I Breast Cancer Stage II Breast Cancer Stage III Mild Depression Moderate Depression
Interventions
OTHER
No Results Yet
NCT06334952 | RECRUITING | NA
60 Participants

Efficacy of Personnalized Transcranial Direct Current Electrical Stimulation (tDCS) in Drug-resistant Epileptic

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-12-18
Completion: 2026-12-18
Conditions
Epilepsy Drug Resistant Epilepsy
Interventions
DEVICE
No Results Yet
NCT06333392 | RECRUITING | NA
1070 Participants

Total Underwater Colonoscopy (TUC) for Improved Colorectal Cancer Screening: A Randomized Controlled Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-10-23
Completion: 2026-12-31
Conditions
Colorectal Neoplasia Screening Colonoscopy Colorectal Cancer Colorectal Cancer Screening Vasovagal Reaction
Interventions
PROCEDURE
No Results Yet
NCT06321757 | RECRUITING
501 Participants

PREVAIL Paclitaxel-coated Balloon in Small Coronary Disease and High-bleeding Risk Patients

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2024-02-26
Completion: 2026-01-30
Conditions
Coronary Artery Disease
Interventions
DEVICE
No Results Yet
NCT06319820 | RECRUITING | PHASE3
641 Participants

A Study to Evaluate TAR-210 Versus Single Agent Intravesical Cancer Treatment in Participants With Bladder Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-04-18
Completion: 2028-06-28
Conditions
Non-Muscle Invasive Bladder Cancer
Interventions
COMBINATION_PRODUCT DRUG
No Results Yet
NCT06316947 | ACTIVE_NOT_RECRUITING | NA
15 Participants

Developing and Pilot Testing an Intervention to Reduce Household Shisha Smoke Exposure Within Somali Homes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-09-03
Completion: 2026-03-01
Conditions
Shisha
Interventions
RADIATION
No Results Yet
NCT06311487 | ACTIVE_NOT_RECRUITING | NA
20 Participants

Time and Nutrient-Dependent Effects of Aerobic Exercise on Metabolism in Adults (TANDEM Study)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-04-15
Completion: 2026-03-01
Conditions
Overweight and Obesity Healthy
Interventions
BEHAVIORAL
No Results Yet
NCT06303505 | RECRUITING | PHASE1/PHASE2
200 Participants

FiH Study to Investigate Safety, PK and Efficacy of the NaPi2b ADC TUB-040 in Patients With PROC or r/r Adenocarcinoma NSCLC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-06-12
Completion: 2027-01-31
Conditions
Ovarian Cancer Non-small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT06300229 | COMPLETED | PHASE1/PHASE2
42 Participants

NAPO - Novel Approach for Oligospermia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-03-01
Completion: 2025-01-29
Conditions
Infertility, Male
Interventions
DRUG
No Results Yet
NCT06298357 | ACTIVE_NOT_RECRUITING | PHASE1
16 Participants

Virtual Reality Gaming for Exercise and Mindfulness Among Pediatric Cancer Rehabilitation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-06-27
Completion: 2025-12-01
Conditions
Pediatric Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT06295692 | ACTIVE_NOT_RECRUITING | PHASE3
19 Participants

A Study of JNJ-77242113 for the Treatment of Participants With Generalized Pustular Psoriasis or Erythrodermic Psoriasis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-02-09
Completion: 2025-01-14
Conditions
Generalized Pustular Psoriasis Erythrodermic Psoriasis
Interventions
DRUG
No Results Yet
NCT06292156 | COMPLETED | NA
68 Participants

tACS Treatment for Cognitive Impairments in Methamphetamine Addicts

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-12-30
Completion: 2024-12-30
Conditions
Methamphetamine Abuse
Interventions
DEVICE
No Results Yet
NCT06287567 | COMPLETED | PHASE2
17 Participants

Lusutrombopag in the Treatment of Immune Thrombocytopenia (ITP)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-04-17
Completion: 2024-11-13
Conditions
Idiopathic Thrombocytopenic Purpura Immune Thrombocytopenia
Interventions
DRUG
No Results Yet
NCT06285591 | COMPLETED | PHASE2
160 Participants

Lactobacillus Reuteri Alleviates Oral Mucositis in Patients Undergoing Radiotherapy for Malignant Head and Neck Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-03-01
Completion: 2025-01-01
Conditions
Head and Neck Malignant Tumors
Interventions
DRUG RADIATION
No Results Yet
NCT06285318 | RECRUITING
900 Participants

A Study of Clinical Outcomes in Patients With Relapsed/Refractory Multiple Myeloma (RRMM) Treated With T-cell Redirectors Outside of Clinical Trials

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2023-12-18
Completion: 2026-06-30
Conditions
Relapsed/Refractory Multiple Myeloma (RRMM)
Interventions
OTHER
No Results Yet
NCT06280664 | RECRUITING
40 Participants

Efficacy Of Hiatal Closure For GERD

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2020-10-02
Completion: 2028-10-31
Conditions
Gastro Esophageal Reflux
No Results Yet
NCT06277999 | COMPLETED
7 Participants

C.Difficile Observational Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2024-04-22
Completion: 2024-12-17
Conditions
Clostridium Infections
No Results Yet
NCT06262139 | RECRUITING | PHASE1/PHASE2
12 Participants

Evaluation of a Targeted Magnetic Resonance Imaging Contrast Agent in Prostate Cancer Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-07-25
Completion: 2026-12-31
Conditions
MRI Scan
Interventions
DRUG
No Results Yet
NCT06256991 | RECRUITING | PHASE4
44 Participants

Potassium Correction for RAAS Optimization in Chronic Kidney Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-04-01
Completion: 2026-12-31
Conditions
Chronic Kidney Diseases Hyperkalemia Hypertension
Interventions
DRUG
No Results Yet
NCT06253221 | ACTIVE_NOT_RECRUITING | PHASE3
44 Participants

A Study to Evaluate Mavacamten in Adolescents With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-04-17
Completion: 2025-11-25
Conditions
Cardiomyopathy, Hypertrophic
Interventions
DRUG
No Results Yet
NCT06247254 | ACTIVE_NOT_RECRUITING | NA
86 Participants

Telehealth-Enhanced Assessment and Management

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2024-11-15
Completion: 2027-11-30
Conditions
Blood Pressure
Interventions
BEHAVIORAL
No Results Yet
NCT06236607 | RECRUITING | NA
140 Participants

Hybrid Closed Loop Effectiveness Trial in Adults With Type 1 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2025-02-27
Completion: 2028-09-30
Conditions
Diabetes Mellitus, Type 1 Diabetes Complications
Interventions
DEVICE OTHER
No Results Yet
NCT06235580 | RECRUITING
1000 Participants

Genotype-phenotype Characterization Study on Genetic Diseases With Immune and Neurological Dysfunctions

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2015-12-28
Completion: 2030-12-27
Conditions
Genetic Diseases Immune Dysfunction Neurological Disease Autoimmune Diseases
Interventions
OTHER
No Results Yet
NCT06235229 | RECRUITING | PHASE1/PHASE2
110 Participants

A Study of GC012F in Patients With Relapsed/Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-12-26
Completion: 2026-03-02
Conditions
Multiple Myeloma
Interventions
BIOLOGICAL
No Results Yet
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