Clinical Trials
Showing trials with last updates posted in 2025.
104
Participants
Comparison of Allegra vs Sapien Transcatheter Aortic Valves in Valve-In-Valve Indication
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-02-01
Completion:
2026-11-01
Conditions
Aortic Valve Stenosis
Structural Valve Deterioration
Interventions
DEVICE
No Results Yet
30
Participants
Sacituzumab Tirumotecan (MK-2870) as Monotherapy and in Combination With Pembrolizumab in Participants With Advanced Solid Tumors (MK-2870-008)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-10-26
Completion:
2026-06-30
Conditions
Non-small Cell Lung Cancer
Solid Tumors
Programmed Cell Death-1 (PD1, PD-1)
Programmed Cell Death 1 Ligand 1(PDL1, PD-L1)
Programmed Cell Death 1 Ligand 2 (PDL2, PD-L2)
Interventions
BIOLOGICAL
DRUG
No Results Yet
252
Participants
A Study of JNJ-77242113 in Participants With Moderately to Severely Active Ulcerative Colitis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-10-09
Completion:
2024-09-26
Conditions
Colitis, Ulcerative
Interventions
DRUG
No Results Yet
24
Participants
Autologous CD8+ and CD4+ Transgenic T Cells Expressing High Affinity KRASG12V Mutation-Specific T Cell Receptors (FH-A11KRASG12V-TCR) in Treating Patients With Metastatic Solid Tumor Cancers With KRAS G12V Mutations
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-12-15
Completion:
2028-01-01
Conditions
Metastatic Malignant Solid Neoplasm
Interventions
DRUG
PROCEDURE
BIOLOGICAL
No Results Yet
60
Participants
A US Study to Evaluate Transarterial Radioembolization (TARE) in Combination With Durvalumab and Bevacizumab Therapy in People With Unresectable Hepatocellular Carcinoma Amenable to TARE
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-02-13
Completion:
2026-10-23
Conditions
Hepatocellular Carcinoma (HCC)
Interventions
DRUG
PROCEDURE
No Results Yet
180
Participants
Testing the Effectiveness of WW Clinic GLP1
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2024-01-18
Completion:
2024-10-17
Conditions
Weight Loss
Obesity
10
Participants
The Safety and Tolerability Study With ER2001 Intravenous Injection in Adults With Early Manifest Huntington's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-04-04
Completion:
2025-01-31
Conditions
Huntington Disease
Interventions
DRUG
No Results Yet
72
Participants
A Study of CRD3874-SI in People With Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-08-25
Completion:
2029-08-31
Conditions
Sarcoma
Merkel Cell Carcinoma
Interventions
DRUG
No Results Yet
151
Participants
Predicting Outcome of Cytoreduction in Advanced Ovarian Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-01-02
Completion:
2025-12-15
Conditions
Ovarian Cancer Stage III
Ovarian Cancer Stage IV
Interventions
DIAGNOSTIC_TEST
No Results Yet
42
Participants
A Study to Test Whether Spesolimab Helps People With Generalized Pustular Psoriasis (GPP) Who Need Treatment for Repeated Flares
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-10-22
Completion:
2026-07-23
Conditions
Generalized Pustular Psoriasis
Interventions
DRUG
No Results Yet
568
Participants
COPD Case Finding In Nottingham and District: C-FIND COPD A Pilot Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2023-09-21
Completion:
2025-12-31
Conditions
COPD
No Results Yet
260
Participants
Mosunetuzumab-Lenalidomide Versus Investigator Choices in Patients With Relapsed or Refractory Marginal Zone Lymphoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-09-05
Completion:
2027-09-30
Conditions
Marginal Zone Lymphoma
Interventions
DRUG
No Results Yet
84
Participants
Sacubitril-Valsartan in Heart Failure With Preserved Ejection Fraction and Secondary Mitral Valve Regurgitation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-02-29
Completion:
2025-09-22
Conditions
Heart Failure With Preserved Ejection Fraction
Functional Mitral Regurgitation
Interventions
DRUG
No Results Yet
111
Participants
Evaluating a School-based Social and Material Needs Identification System to Prevent Youth Violence Involvement
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2024-02-21
Completion:
2025-10-01
Conditions
Violence, Physical
Maltreatment, Child
Interventions
OTHER
No Results Yet
25
Participants
Open Trial of Biofeedback for Respiratory Symptoms
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2021-08-01
Completion:
2027-07-31
Conditions
Shortness of Breath/Dyspnea
No Results Yet
21
Participants
Protection Response to Cellular Stress in BPAN's Patient Study
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2023-10-23
Completion:
2025-10-23
Conditions
Children and Adults With BPAN Carrying Pathogenic Variants of WDR45
Interventions
BIOLOGICAL
No Results Yet
47
Participants
Stress-Echography in Hereditary Haemorrhagic Telangiectasia Patient With Hepatic Involvement
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-08-03
Completion:
2025-01-14
Conditions
Hereditary Hemorrhagic Telangiectasia
Rendu Osler Disease
Interventions
OTHER
No Results Yet
161
Participants
Prospective Clinical Evaluation of BD NRFit™ Devices and Accessories.
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2023-07-24
Completion:
2024-05-28
Conditions
Anesthesia
Analgesia
Interventions
DEVICE
25
Participants
Influence of Gait and Running on Foot Posture
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2023-06-20
Completion:
2023-06-20
Conditions
Foot Pronation in Healthy Adult
Interventions
BEHAVIORAL
No Results Yet
40
Participants
Pilot Testing of a Mobile Phone App-based Intervention for Parents of Children With Autism Spectrum Disorder (ASD)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-08-01
Completion:
2024-08-05
Conditions
Autism Spectrum Disorder
Parent-Child Relations
Interventions
OTHER
No Results Yet
156
Participants
Weaning With Tracheostomy - an Observational Study on Patient-centered Outcomes
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2023-05-08
Completion:
2024-11-30
Conditions
Weaning Failure
Mechanical Ventilation
Patient-centered Care
No Results Yet
5
Participants
A Novel Balance Program to Improve Balance in People With Parkinson's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-09-20
Completion:
2023-12-18
Conditions
Rehabilitation Exercise
Physical Therapy
Interventions
OTHER
No Results Yet
60
Participants
Serum Concentration of Endogenous Estrogens and Sirtuin-1 After Administration of Atorvastatin and Quercetin:
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-10-03
Completion:
2023-12-23
Conditions
Coronary Artery Disease
Menopause
Interventions
DIETARY_SUPPLEMENT
No Results Yet
234
Participants
Effect of Partially Hydrolyzed, Whey-based Infant Formulas on Growth and Tolerability in Healthy Term Infants
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-08-17
Completion:
2027-12-31
Conditions
Infant Nutritional Physiological Phenomena
Infant Formula
Infant Health
Infant Development
Growth and Development
Interventions
OTHER
No Results Yet
13
Participants
Grasp-Release Assessment of a Networked Neuroprosthesis Device
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-01-23
Completion:
2027-12-01
Conditions
Spinal Cord Injury at C5-C7 Level
Spinal Cord Injuries
Spinal Cord Injury Cervical
Interventions
DEVICE
No Results Yet
204
Participants
Impact, Feasibility, and Acceptability of Bladder Basics
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-08-22
Completion:
2024-11-10
Conditions
Health Knowledge, Attitudes, Practice
Interventions
OTHER
120
Participants
Metformin Treatment on Cognitive Impairment of Schizophrenia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-05-08
Completion:
2026-12-12
Conditions
Schizophrenia
Interventions
DRUG
OTHER
No Results Yet
60
Participants
Intravenous Administration of Magnesium Sulfate in Laparoscopic Hysterectomy Cases
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2024-01-20
Completion:
2024-03-30
Conditions
Laparoscopic Hysterectomy
Magnesium Sulfate
General Anesthesia
Interventions
DRUG
No Results Yet
300
Participants
Health Behavior Intervention for Adults With Type 1 Diabetes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-12-20
Completion:
2028-07-31
Conditions
Type1diabetes
Interventions
BEHAVIORAL
No Results Yet
103
Participants
NEXUS - Next Generation Health Through 2D & 3D Fetal UltraSound; Building Connections to Support Maternal-fetal Health
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-06-08
Completion:
2025-11-30
Conditions
Pregnancy Related
Substance Use
Mental Health Issue
Interventions
BEHAVIORAL
No Results Yet
11
Participants
Familial Hyperlipidemia Family Registry
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2023-02-17
Completion:
2025-05-29
Conditions
Familial Hyperlipidemia
40
Participants
Fluorescence Imaging With Indocyanine Green(ICG) in Endoscopic Spinal Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-04-11
Completion:
2025-12-14
Conditions
Disc Herniation
Interventions
DRUG
DEVICE
No Results Yet
15
Participants
Aldesleukin With Nivolumab and Standard Chemotherapy for Treatment of Gastric Cancer With Peritoneal Metastasis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-11-29
Completion:
2027-04-15
Conditions
Clinical Stage IV Gastric Cancer AJCC v8
Gastric Adenocarcinoma
Gastroesophageal Junction Adenocarcinoma
Metastatic Gastric Carcinoma
Metastatic Malignant Neoplasm in the Peritoneum
Interventions
BIOLOGICAL
PROCEDURE
DRUG
No Results Yet
120
Participants
A Phase 2 Clinical Study of MIL62 in Systemic Lupus Erythematosus
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-05-26
Completion:
2026-02-28
Conditions
Systemic Lupus Erythematosus
Interventions
DRUG
No Results Yet
2000
Participants
Genetic Carbohydrate Maldigestion as a Model to Study Food Hypersensitivity
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2024-07-23
Completion:
2025-09-30
Conditions
Irritable Bowel Syndrome (IBS)
Sucrase Isomaltase Deficiency
Interventions
OTHER
No Results Yet
981
Participants
A Study to Compare Darolutamide Given With Androgen Deprivation Therapy (ADT) With ADT in Men With Hormone Sensitive Prostate Cancer and Raise of Prostate Specific Antigen (PSA) Levels After Local Therapies
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-04-03
Completion:
2027-07-30
Conditions
Biochemically Recurrent Prostate Cancer
Interventions
DRUG
OTHER
No Results Yet
120
Participants
Dialysis Geriatric Care Model
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2025-12-01
Completion:
2028-08-31
Conditions
Chronic Kidney Diseases
Dialysis
Geriatric
Interventions
BEHAVIORAL
No Results Yet
60
Participants
Developing an Integrated Psychotherapy With Cognitive-behavioral Therapy and Biofeedback Therapy for Somatic Symptom Disorder
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-07-11
Completion:
2026-06-30
Conditions
Somatic Symptom Disorder
Interventions
BEHAVIORAL
No Results Yet
90
Participants
A Novel Wearable Digital Biomarker for Detecting Changes in Multiple Sclerosis (MS) Condition
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2023-07-01
Completion:
2026-09-01
Conditions
Multiple Sclerosis
No Results Yet
10
Participants
A Study of Romosozumab in Women With Multiple Myeloma and Osteoporosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2023-03-07
Completion:
2027-03-31
Conditions
Osteoporosis
Multiple Myeloma
Interventions
DRUG
No Results Yet
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