Clinical Trials
Showing trials with last updates posted in 2025.
100
Participants
Utility of 18FDOPA PET/MRI for Focal Hyperinsulinism
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2020-09-10
Completion:
2030-01-01
Conditions
Hyperinsulinism
Interventions
DRUG
No Results Yet
60
Participants
Reduced Intensity Allogeneic HCT in Advanced Hematologic Malignancies w/T-Cell Depleted Graft
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-09-07
Completion:
2027-11-30
Conditions
Allogeneic Hematopoietic Cell Transplantation (HCT)
Advanced Hematologic Malignancies
Acute Leukemia
Chronic Myelogenous Leukemia
Myelodysplastic Syndromes
Myeloproliferative Disorders
Interventions
DRUG
DEVICE
No Results Yet
48
Participants
A Study of Ustekinumab or Guselkumab in Pediatric Participants With Active Juvenile Psoriatic Arthritis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-08-30
Completion:
2026-12-10
Conditions
Arthritis, Juvenile
Interventions
DRUG
No Results Yet
587
Participants
A Study of Teclistamab in Combination With Daratumumab Subcutaneously (SC) (Tec-Dara) Versus Daratumumab SC, Pomalidomide, and Dexamethasone (DPd) or Daratumumab SC, Bortezomib, and Dexamethasone (DVd) in Participants With Relapsed or Refractory Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-10-14
Completion:
2028-12-08
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
350
Participants
A Study to Test the Efficacy and Safety of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-12-07
Completion:
2026-04-06
Conditions
Stereotypical Prolonged Seizures
Interventions
DRUG
OTHER
No Results Yet
300
Participants
A Study to Test the Safety and Tolerability of Staccato Alprazolam in Study Participants 12 Years of Age and Older With Stereotypical Prolonged Seizures
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-02-03
Completion:
2028-11-30
Conditions
Stereotypical Prolonged Seizures
Interventions
DRUG
No Results Yet
60
Participants
Adjuvant Continuous Infusion of Nefopam Versus Standard of Care in Mechanically Ventilated Critically Ill Patients: Randomized Double-blind Controlled Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-10-01
Completion:
2023-03-01
Conditions
Analgesia
Critical Illness
Mechanical Ventilation
Sedation
Interventions
DRUG
No Results Yet
18
Participants
Generate Real World Data On Tofacitinib Induction Therapy and Changes In Clinical and Patient Reported Outcomes.
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2022-03-28
Completion:
2024-04-30
Conditions
Ulcerative Colitis
Interventions
OTHER
104
Participants
A Study to Evaluate the Efficacy and Safety of Rozanolixizumab in Adult Participants With Myelin Oligodendrocyte Glycoprotein (MOG) Antibody-associated Disease (MOG-AD)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-02-02
Completion:
2027-05-06
Conditions
Myelin Oligodendrocyte Glycoprotein Antibody-associated Disease (MOG-AD)
Interventions
DRUG
OTHER
No Results Yet
15
Participants
Impact Of Muscle Vibration On Gait Control
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-10-04
Completion:
2027-12-31
Conditions
Muscle
Interventions
DEVICE
No Results Yet
61
Participants
KZR-261 in Subjects With Advanced Solid Malignancies
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-09-30
Completion:
2025-01-17
Conditions
Advanced/Metastatic Solid Tumor
Interventions
DRUG
6
Participants
Atezolizumab and Cabozantinib for the Treatment of Recurrent Glioblastoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-09-23
Completion:
2027-12-31
Conditions
Recurrent Glioblastoma
Recurrent Gliosarcoma
Interventions
BIOLOGICAL
DRUG
No Results Yet
80
Participants
Separation Versus Integrated Approach in Combining ECMO With CRRT
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-04-01
Completion:
2025-03-10
Conditions
AKI
Interventions
DEVICE
No Results Yet
26
Participants
Skin Fibrosis Analysis by Raman Spectroscopy in Systemic Sclerosis
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2021-04-08
Completion:
2023-07-21
Conditions
Validation of Raman Spectroscopy Usefulness in Systemic Sclerosis
No Results Yet
70
Participants
Functional and Mechanistic Characterization of Limb Ulcers in Patients With Sickle Cell Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-02-09
Completion:
2023-10-03
Conditions
Ulcer
Anemia
Sickle Cell Disease
Interventions
DIAGNOSTIC_TEST
No Results Yet
195
Participants
Natural History of KSHV-Associated Multicentric Castleman s Disease
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2021-11-17
Completion:
2034-01-01
Conditions
Multicentric Castleman s Disease
No Results Yet
315
Participants
Phase III Study to Assess AZD9833+ CDK4/6 Inhibitor in HR+/HER2-MBC With Detectable ESR1m Before Progression (SERENA-6)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-06-30
Completion:
2025-06-30
Conditions
ER-Positive HER2-Negative Breast Cancer
Interventions
DRUG
No Results Yet
48
Participants
Understanding Host-pathogen Interaction in the Respiratory Mucosa During Pregnancy
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2022-03-02
Completion:
2023-09-27
Conditions
Pregnancy Related
Innate Inflammatory Response
Interventions
OTHER
No Results Yet
712
Participants
Treatment Combination of Durvalumab, Tremelimumab and Enfortumab Vedotin or Durvalumab and Enfortumab Vedotin in Patients With Muscle Invasive Bladder Cancer Ineligible to Cisplatin or Who Refuse Cisplatin
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-08-05
Completion:
2026-04-30
Conditions
Muscle Invasive Bladder Cancer
Interventions
DRUG
PROCEDURE
No Results Yet
60
Participants
Reflex Excitability in Post-stroke Stiff-Knee Gait
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-06-11
Completion:
2025-06-11
Conditions
Stroke
Chronic Stroke
Gait, Hemiplegic
Gait, Spastic
Gait Disorder, Sensorimotor
Gait Disorders, Neurologic
Walking, Difficulty
Interventions
OTHER
DEVICE
No Results Yet
405
Participants
A Study of Guselkumab Administered Subcutaneously in Bio-naive Participants With Active Psoriatic Arthritis Axial Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-08-30
Completion:
2026-08-04
Conditions
Arthritis, Psoriatic
Interventions
DRUG
No Results Yet
163
Participants
A Study of TAR-200 in Combination With Cetrelimab and Cetrelimab Alone in Participants With Muscle-Invasive Urothelial Carcinoma of the Bladder
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-07-07
Completion:
2025-02-04
Conditions
Urinary Bladder Neoplasms
Interventions
DRUG
BIOLOGICAL
No Results Yet
Individual Patient Expanded Access IND for Selexipag (Uptravi) in Participants With Non-healing Wound, Buerger's Disease
Study Type:
EXPANDED_ACCESS
Last Updated:
2025-12-19
Conditions
Non-healing Wound
Thromboangiitis Obliterans
Interventions
DRUG
No Results Yet
50
Participants
Validation of the ANI in Perpubescent Patients in Pediatric Intensive Care Unit.
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2021-06-29
Completion:
2023-11-22
Conditions
Pain
Pediatric ALL
No Results Yet
42
Participants
Phase II Trial to Evaluate Safety and Efficacy of GM-CSF/Sargramostim in Alzheimer's Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-06-01
Completion:
2026-11-30
Conditions
Alzheimer Disease
Interventions
DRUG
No Results Yet
658
Participants
A Study to Test the Long-term Treatment of Bimekizumab in Study Participants With Moderate to Severe Hidradenitis Suppurativa
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-05-27
Completion:
2026-07-28
Conditions
Hidradenitis Suppurativa
Interventions
DRUG
No Results Yet
64
Participants
Study of BGB-11417 in Adult Participants With Mature B-cell Malignancies
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-07-05
Completion:
2026-04-30
Conditions
Mature B-cell Malignancies
Interventions
DRUG
No Results Yet
150
Participants
ELEVATE, a Registry of Patients With Acute Hepatic Porphyria (AHP)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2021-04-26
Completion:
2027-04-01
Conditions
Acute Hepatic Porphyria
No Results Yet
178
Participants
Combination of Baricitinib and Anti-TNF in Rheumatoid Arthritis
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-07-15
Completion:
2027-03-31
Conditions
Rheumatoid Arthritis
Interventions
DRUG
No Results Yet
78
Participants
A Clinical Observational Study of SARS-CoV-2 Specific CD8 T-Cell Responses to COVID-19 Vaccines in Humans
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2021-04-20
Completion:
2026-12-31
Conditions
COVID-19
No Results Yet
22
Participants
Efficacy of FES Cycling After a Severe Form of COVID-19
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-06-02
Completion:
2024-10-02
Conditions
Covid19
Ventilators, Mechanical
Respiratory Distress Syndrome
Interventions
BEHAVIORAL
No Results Yet
6
Participants
Non-Contrast Perfusion Using Arterial Spin Labeled MR Imaging for Assessment of Therapy Response in Metastatic Renal Cell Carcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-03-24
Completion:
2023-04-04
Conditions
Renal Cell Carcinoma
Interventions
OTHER
160
Participants
Spectroscopy in Ovarian Cancer
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2021-06-28
Completion:
2023-10-01
Conditions
Ovarian Cancer
Ovarian Neoplasms
Ovary Cyst
Ovary Disease
No Results Yet
316
Participants
A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Participants With Breast Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-06-22
Completion:
2029-05-30
Conditions
Inoperable, Locally Advanced or Metastatic, ER-positive Breast Cancer
Interventions
DRUG
No Results Yet
50
Participants
Comparing the Addition of an Anti-Cancer Drug, Pomalidomide, to the Usual Chemotherapy Treatment (Daunorubicin and Cytarabine Liposome) in Newly Diagnosed Acute Myeloid Leukemia With Myelodysplastic Syndrome-Related Changes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-08-24
Completion:
2024-11-21
Conditions
Acute Myeloid Leukemia
Acute Myeloid Leukemia Post Cytotoxic Therapy
Acute Myeloid Leukemia With Multilineage Dysplasia
Chronic Myelomonocytic Leukemia
Myelodysplastic Syndrome
Myeloproliferative Neoplasm
Interventions
PROCEDURE
DRUG
360
Participants
Coronary CT Angio Evaluating Graft Patency in ACS Patients Treated With DAPT or Single ASA After CABG (CoCAP)
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2021-05-17
Completion:
2026-02-01
Conditions
Acute Coronary Syndrome
Coronary Bypass Stenosis
No Results Yet
225
Participants
Characterizing Inflammatory Profiles and Suicidal Behavior in Adolescents
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2021-04-28
Completion:
2025-06-15
Conditions
Suicide and Depression
Interventions
OTHER
No Results Yet
0
Participants
Chitogel CSK-4 Gel as Packing in Tympanoplasty Surgery
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-19
Start Date:
2021-01-14
Completion:
2021-11-03
Conditions
Tympanoplasty Surgery
Interventions
BIOLOGICAL
No Results Yet
90
Participants
PrEP at a Syringe Services Program
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2022-02-01
Completion:
2024-11-11
Conditions
Hiv
Substance Use Disorders
Interventions
DRUG
BEHAVIORAL
380
Participants
A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-19
Start Date:
2021-04-28
Completion:
2027-03-31
Conditions
Depression
Bipolar I Disorder
Interventions
DRUG
No Results Yet
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