MedDataX Logo

Clinical Trials

Showing trials with last updates posted in 2025.

NCT04773457 | ACTIVE_NOT_RECRUITING
220 Participants

Neutrophil Phenotypic Profiling and Surgical Site Infections in Surgical Patients

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2023-04-01
Completion: 2026-12-01
Conditions
Surgical Site Infection
Interventions
OTHER
No Results Yet
NCT04768309 | COMPLETED | NA
20 Participants

Impact of Intestinal Microbiota on Uremic Toxins Productions

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2021-06-04
Completion: 2021-07-13
Conditions
CKD Uremia
Interventions
OTHER
No Results Yet
NCT04741269 | COMPLETED
98 Participants

Asymmetric Lack of Knee Flexion as a Symptom of DLM in Children

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2020-09-01
Completion: 2020-11-01
Conditions
Highlights a New Clinical Sign Which Point Out a Meniscus Posterior Luxation Because of a MCA-type DLM
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT04714840 | ACTIVE_NOT_RECRUITING | NA
181 Participants

Telehealth Based Intervention to Improve Functional Capacity in Survivors of Childhood Cancer With Significantly Limited Exercise Tolerance

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2021-02-08
Completion: 2025-09-15
Conditions
Childhood Cancer Mobility Limitation
Interventions
OTHER
No Results Yet
NCT04691960 | ACTIVE_NOT_RECRUITING | PHASE2
18 Participants

A Pilot Study of Ketogenic Diet and Metformin in Glioblastoma: Feasibility and Metabolic Imaging

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2016-08-31
Completion: 2026-06-30
Conditions
Glioblastoma
Interventions
OTHER DRUG
No Results Yet
NCT04691297 | ACTIVE_NOT_RECRUITING | NA
153 Participants

Digitally Enhanced Smoking Cessation for High Risk Smokers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2021-02-01
Completion: 2023-02-01
Conditions
Smoking Smoking Cessation Lung Cancer Screening Smoking, Tobacco Smoking Behaviors
Interventions
OTHER
No Results Yet
NCT04659616 | RECRUITING | PHASE1
32 Participants

Pemigatinib After Chemotherapy for the Treatment of Newly Diagnosed Acute Myeloid Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2021-01-14
Completion: 2026-12-31
Conditions
Acute Myeloid Leukemia
Interventions
PROCEDURE DRUG
No Results Yet
NCT04658862 | ACTIVE_NOT_RECRUITING | PHASE3
518 Participants

A Study of TAR-200 in Combination With Cetrelimab Versus Concurrent Chemoradiotherapy in Participants With Muscle-invasive Bladder Cancer (MIBC) of the Bladder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2020-12-07
Completion: 2026-12-30
Conditions
Urinary Bladder Neoplasms
Interventions
BIOLOGICAL DRUG RADIATION
No Results Yet
NCT04634552 | RECRUITING | PHASE2
510 Participants

A Study of Talquetamab in Participants With Relapsed or Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2021-02-01
Completion: 2026-03-31
Conditions
Hematological Malignancies
Interventions
DRUG
No Results Yet
NCT04626024 | RECRUITING | PHASE2
100 Participants

Safety And Efficacy Of TKI Cessation For CML Patients With Stable Molecular Response In A Real World Population

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2020-12-22
Completion: 2028-11-15
Conditions
Chronic Myeloid Leukemia Chronic Myeloid Leukemia, BCR/ABL-Positive, in Remission Chronic Myeloid Leukemia in Remission
Interventions
OTHER DRUG
No Results Yet
NCT04625478 | COMPLETED
50 Participants

Clinical Relevance of Intracellular Staphylococci in BOne and Joint Infections

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2020-12-01
Completion: 2021-09-20
Conditions
Staphylococcus Bone and Joint Infection
Interventions
OTHER
No Results Yet
NCT04619420 | ACTIVE_NOT_RECRUITING | PHASE2
523 Participants

A Study of JNJ-63733657 in Participants With Early Alzheimer's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2021-01-06
Completion: 2025-10-17
Conditions
Alzheimer Disease Cognitive Dysfunction Dementia
Interventions
DRUG
No Results Yet
NCT04590885 | ACTIVE_NOT_RECRUITING | NA
440 Participants

Coping Together: Couple-based Interventions for Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2020-10-20
Completion: 2025-12-30
Conditions
Advanced Cancer
Interventions
BEHAVIORAL
No Results Yet
NCT04586426 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
228 Participants

A Study of the Combination of Talquetamab and Teclistamab in Participants With Relapsed or Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2020-12-15
Completion: 2025-03-18
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT04585503 | COMPLETED | NA
20 Participants

Feasibility Study of Cortical Recording Depolarizations in Brain-injured Patients, and Their Use as Biomarkers of New Lesions.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2021-01-01
Completion: 2023-04-07
Conditions
Brain Lesion Head Trauma Subarachnoid Hemorrhage
Interventions
DEVICE
No Results Yet
NCT04579848 | ACTIVE_NOT_RECRUITING | PHASE4
163 Participants

Methotrexate in Erosive Inflammatory Hand Osteoarthritis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2021-08-12
Completion: 2026-12-31
Conditions
Hand Osteoarthritis Erosive Osteoarthritis
Interventions
DRUG
No Results Yet
NCT04579380 | ACTIVE_NOT_RECRUITING | PHASE2
217 Participants

Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2021-01-11
Completion: 2023-11-01
Conditions
Uterine Neoplasms Uterine Cervical Neoplasms Biliary Tract Neoplasms Urologic Neoplasms Carcinoma, Non-Small-Cell Lung HER2 Mutations Breast Neoplasms
Interventions
DRUG
Results Available
NCT04552834 | ACTIVE_NOT_RECRUITING
500 Participants

Alterations of the Microbiome During Critical Illness With Short and Long Term Clinical Outcomes

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2020-09-15
Completion: 2026-06-01
Conditions
Critical Illness Microbiome
No Results Yet
NCT04550104 | RECRUITING | PHASE1
200 Participants

A Platform Study of Novel Agents in Combination With Radiotherapy in NSCLC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2021-03-17
Completion: 2026-03-31
Conditions
Non Small Cell Lung Cancer
Interventions
RADIATION DRUG
No Results Yet
NCT04539964 | ACTIVE_NOT_RECRUITING | PHASE3
243 Participants

Vagus Nerve Stimulation for Moderate to Severe Rheumatoid Arthritis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2021-01-11
Completion: 2024-05-16
Conditions
Rheumatoid Arthritis
Interventions
PROCEDURE DRUG DEVICE
Results Available
NCT04517279 | COMPLETED | NA
113 Participants

Peer Approaches to Substances in Early Psychosis Programs: A Pilot Study of a Peer-Led Intervention

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2023-08-22
Completion: 2025-07-25
Conditions
Substance Use Psychotic Disorders
Interventions
BEHAVIORAL
No Results Yet
NCT04495296 | RECRUITING | PHASE1/PHASE2
320 Participants

A Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of TST001 in Advanced or Metastatic Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2020-08-13
Completion: 2026-06-25
Conditions
Advanced Cancer
Interventions
DRUG
No Results Yet
NCT04481919 | ACTIVE_NOT_RECRUITING | PHASE2
474 Participants

Randomized Controlled Trial of urinE chemiStry Guided aCute heArt faiLure treATmEnt (ESCALATE)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2022-05-01
Completion: 2026-09-30
Conditions
Heart Failure Acute Heart Failure
Interventions
DRUG
No Results Yet
NCT04464707 | COMPLETED | PHASE3
292 Participants

A Study to Test if Fremanezumab is Effective in Preventing Chronic Migraine in Participants 6 to 17 Years of Age

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2020-09-24
Completion: 2024-11-29
Conditions
Migraine
Interventions
DRUG
Results Available
NCT04447118 | COMPLETED | PHASE3
151 Participants

Phase 3 Study of Pyrotinib Versus Docetaxel in Patients With Advanced Non-squamous NSCLC Harboring a HER2 Exon 20 Mutation Who Failed Platinum Based Chemotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2020-09-11
Completion: 2023-06-02
Conditions
Non-squamous NSCLC HER2 Exon 20 Mutation
Interventions
DRUG
No Results Yet
NCT04439552 | RECRUITING
60 Participants

fMRI and IVCM Cornea Microscopy of CXL in Keratoconus

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2021-10-04
Completion: 2027-08-31
Conditions
Pain, Postoperative Pain, Chronic Pain, Acute Surgical Injury Surgical Wound Cornea Injury Cornea Keratoconus
No Results Yet
NCT04437225 | ACTIVE_NOT_RECRUITING | NA
15 Participants

Renal Metabolism of Glycolate to Oxalate

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2020-03-12
Completion: 2026-09-01
Conditions
Healthy
Interventions
DIETARY_SUPPLEMENT OTHER
No Results Yet
NCT04435054 | COMPLETED | NA
1000 Participants

Screening for NAFLD-related Advanced Fibrosis in High Risk Population in Diabetology.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2020-10-28
Completion: 2023-10-28
Conditions
Non-Alcoholic Fatty Liver Disease
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT04414540 | ACTIVE_NOT_RECRUITING | PHASE2
20 Participants

Combining Pembrolizumab and Metformin in Metastatic Head and Neck Cancer Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2020-08-31
Completion: 2025-12-31
Conditions
Head and Neck Squamous Cell Carcinoma
Interventions
DRUG
No Results Yet
NCT04411602 | WITHDRAWN | PHASE1
0 Participants

Intermediate IND Severe Illness COVID-19 CP

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2020-04-07
Completion: 2021-04-07
Conditions
Severe Acute Respiratory Syndrome COVID
Interventions
DRUG
No Results Yet
NCT04379921 | COMPLETED | NA
255 Participants

Improving Spine Surgical Care With Real-Time Objective Patient Tracking Using the Apple Watch

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2020-09-01
Completion: 2024-11-30
Conditions
Spine Disease Spine Degeneration Spinal Stenosis Surgery Spine Fusion
Interventions
DEVICE
Results Available
NCT04378439 | RECRUITING | NA
141 Participants

Appalachian Partnership to Reduce Disparities (Aim 2)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2022-04-01
Completion: 2026-05-31
Conditions
HIV/AIDS STI HCV
Interventions
BEHAVIORAL
No Results Yet
NCT04361656 | WITHDRAWN
0 Participants

The Effect of Adding Lubiprostone to Standard Large-Volume PEG-ELS on The Quality of Inpatient Colonoscopy Preparation

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2020-05-01
Completion: 2021-02-04
Conditions
Colonoscopy Preparation
Interventions
DRUG
No Results Yet
NCT04360538 | ACTIVE_NOT_RECRUITING
500 Participants

Long Term Outcomes of Patients With COVID-19

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2020-04-08
Completion: 2026-06-01
Conditions
Critical Illness Corona Virus Infection Respiratory Failure Covid-19
Interventions
OTHER
No Results Yet
NCT04349852 | RECRUITING | NA
150 Participants

Verbal Working Memory and Attention Remediation for Adults With Traumatic Brain Injury.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2021-08-01
Completion: 2027-09-01
Conditions
Traumatic Brain Injury
Interventions
BEHAVIORAL
No Results Yet
NCT04325828 | ACTIVE_NOT_RECRUITING | PHASE2
31 Participants

A Study of Apalutamide Combined With GnRH Agonist in Participants With Androgen Receptor Positive Salivary Gland Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2020-04-07
Completion: 2021-06-09
Conditions
Salivary Gland Neoplasms
Interventions
DRUG
Results Available
NCT04281056 | RECRUITING | NA
40 Participants

Impact of Tooth Loss and Denture on Oral Senses and Food Preferences

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2022-03-16
Completion: 2027-04-30
Conditions
Tooth-loss
Interventions
PROCEDURE
No Results Yet
NCT04275973 | COMPLETED | NA
20 Participants

Evaluating Mobility Interventions in the Real World

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2021-09-03
Completion: 2024-08-01
Conditions
Lower Limb Amputation Drop Foot
Interventions
DEVICE
Results Available
NCT04244604 | COMPLETED | NA
71 Participants

Vascular Effects of Acute Sodium (VEAS) Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-19
Start Date: 2021-05-03
Completion: 2025-12-15
Conditions
Sodium Excess Racial Disparities Blood Pressure Cardiovascular Risk Factor
Interventions
OTHER
No Results Yet
NCT04242394 | COMPLETED
1019 Participants

If Chronic Gallbladder Diseases Increase the Incidence of PEC

Study Type: OBSERVATIONAL
Last Updated: 2025-12-19
Start Date: 2020-02-14
Completion: 2024-11-16
Conditions
Cholecystitis
Interventions
PROCEDURE
No Results Yet
Previous
Sorted by latest updates
Next
Showing 40 trials per page