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Impact of Tooth Loss and Denture on Oral Senses and Food Preferences

NCT ID: NCT04281056

Last Updated: 2025-12-19

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-03-16

Study Completion Date

2027-04-30

Brief Summary

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Tooth loss impacts taste abilities and food intake. Present study aims at pertaining the impact of teeth loss and the replacement by means of complete denture on taste and trigeminal abilities, and on food preferences, and taste appetence.

Detailed Description

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Two groups of participants will be included. Participants wearing complete denture for at least one year (n=20) and their matched controls for age, sex, tobacco, and saliva secretion (n=20). Their oral sensory abilities of participants will be assessed including taste (electrogustometric thresholds, chemical taste identification ability) and trigeminal quantitative sensory testing. Food preferences and selectivity (Maitre et al., 2014) and taste appetence (Deglaire et al., 2012) will also be assessed.

Conditions

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Tooth-loss

Keywords

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Teeth loss edentulousness denture tast trigeminal senses oral sensory ability

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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Control

Group Type NO_INTERVENTION

No interventions assigned to this group

Tooth removal

Tooth removal and their replacement by means of a denture Teeth have been removed and replaced by means of dentures for at least one year

Group Type EXPERIMENTAL

Tooth removal and their replacement by means of a denture

Intervention Type PROCEDURE

Teeth have been removed and replaced by means of dentures for at least one year

Interventions

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Tooth removal and their replacement by means of a denture

Teeth have been removed and replaced by means of dentures for at least one year

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

Study Group : being completely edentulous and wearing denture for at least one year, wearing denture during meals, with clean and stable dentures. Controls:

controls Group : dentate subjects (25 teeth at leas, non endodontically treated) with molars in Angle's Class I occlusion, having no functional disturbance of mastication and not undergoing dental treatment at the time of the recording. Matched with subjects of the study group for age, sex, tabacco consumption, and saliva flow rate.

Exclusion Criteria

* Aged under 18 or over 80 Y,
* not consenting to participate
* suffering from dental
* periodontal or gum pain for the last month.
Minimum Eligible Age

18 Years

Maximum Eligible Age

79 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Assistance Publique - Hôpitaux de Paris

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Adeline Braud, Doctor

Role: PRINCIPAL_INVESTIGATOR

Assistance Publique - Hôpitaux de Paris

Locations

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Service odontologie Hôpital Rothschild

Paris, , France

Site Status RECRUITING

Countries

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France

Central Contacts

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Adeline Braud, Doctor

Role: CONTACT

Phone: 01 40 19 39 87

Email: [email protected]

Yves Boucher, Professor

Role: CONTACT

Facility Contacts

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Adeline Braud, Dr

Role: primary

Other Identifiers

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APHP190340

Identifier Type: -

Identifier Source: org_study_id