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Clinical Trials

Showing trials with last updates posted in 2025.

NCT03793335 | ENROLLING_BY_INVITATION
40000 Participants

Individually Tailored Strategies for the Precision Prevention of Gastric Cancer and Colorectal Cancer in the Community

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2019-04-14
Completion: 2025-12-31
Conditions
Gastric Cancer Colorectal Cancer
No Results Yet
NCT03761108 | RECRUITING | PHASE1/PHASE2
387 Participants

Phase 1/2 Study of Linvoseltamab in Adult Patients With Relapsed or Refractory Multiple Myeloma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2019-01-23
Completion: 2033-03-30
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT03728361 | ACTIVE_NOT_RECRUITING | PHASE2
55 Participants

Nivolumab and Temozolomide in Treating Patients With Recurrent or Refractory Small-Cell Lung Cancer or Advanced Neuroendocrine Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-12-31
Completion: 2025-12-17
Conditions
Grade I Neuroendocrine Carcinoma Grade II Neuroendocrine Carcinoma Grade III Neuroendocrine Carcinoma Metastatic Neuroendocrine Carcinoma Neuroendocrine Carcinoma Recurrent Small Cell Lung Carcinoma Refractory Small Cell Lung Carcinoma Lung Cancer Stage IV Large Cell Neuroendocrine Carcinoma Neuroendocrine Tumors Small Cell Lung Cancer Metastatic Small-cell Lung Cancer
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT03723616 | COMPLETED | NA
2588 Participants

Reactions to Warnings on Hookah Ads

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-10-05
Completion: 2021-03-26
Conditions
Reactions to Warnings Hookah Smoking
Interventions
BEHAVIORAL
Results Available
NCT03705416 | ACTIVE_NOT_RECRUITING
250 Participants

Long Term Outcomes of Bariatric Patients Treated With Surgery or Endoscopy

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2019-03-30
Completion: 2026-06-30
Conditions
GERD Obesity
Interventions
PROCEDURE
No Results Yet
NCT03656835 | ACTIVE_NOT_RECRUITING | NA
73 Participants

Nanochip Technology in Monitoring Treatment Response and Detecting Relapse in Participants With Diffuse Large B-Cell Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-09-26
Completion: 2024-11-20
Conditions
Diffuse Large B-Cell Lymphoma Diffuse Large B-Cell Lymphoma Germinal Center B-Cell Type Diffuse Large B-Cell Lymphoma, Not Otherwise Specified High Grade B-Cell Lymphoma
Interventions
PROCEDURE
No Results Yet
NCT03654768 | ACTIVE_NOT_RECRUITING | PHASE2
81 Participants

Testing the Addition of Ruxolitinib to the Usual Treatment (Tyrosine Kinase Inhibitors) for Chronic Myeloid Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-10-24
Completion: 2024-07-01
Conditions
Chronic Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive
Interventions
DRUG OTHER
Results Available
NCT03654079 | NOT_YET_RECRUITING | NA
50 Participants

Patient Centered Simulation For Labor and Delivery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2026-07-31
Completion: 2027-05-31
Conditions
Pregnancy Related
Interventions
OTHER
No Results Yet
NCT03650114 | ACTIVE_NOT_RECRUITING | PHASE3
1882 Participants

Long-term Safety, Tolerability and Effectiveness Study of Ofatumumab in Patients With Relapsing MS

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-12-28
Completion: 2027-12-30
Conditions
Relapsing Multiple Sclerosis
Interventions
BIOLOGICAL
No Results Yet
NCT03617263 | TERMINATED | PHASE2
60 Participants

Saroglitazar Magnesium 4 mg in the Treatment of Nonalcoholic Fatty Liver Disease (NAFLD) in Women With PCOS (EVIDENCES VII)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2019-02-12
Completion: 2024-10-28
Conditions
Non-alcoholic Fatty Liver Disease in Women With PCOS
Interventions
DRUG
Results Available
NCT03608956 | WITHDRAWN
0 Participants

Renal Oxygen Saturation and Its Association With Acute Renal Injury

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2018-05-01
Completion: 2019-03-31
Conditions
Acute Kidney Injury Children Cardiac Surgery
No Results Yet
NCT03598829 | COMPLETED
219 Participants

A Prospective Clinical Trial Comparing Serum Mast Cell Tryptase (SMCT) Levels to Arthrofibrosis Rates Among Primary Total Knee Arthroplasty (TKA) Patients

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2018-07-01
Completion: 2023-11-15
Conditions
Knee Osteoarthritis Arthropathy of Knee Arthrofibrosis
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT03573310 | COMPLETED | PHASE1
114 Participants

A Study of JNJ-64619178, an Inhibitor of PRMT5 in Participants With Advanced Solid Tumors, NHL, and Lower Risk MDS

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-07-13
Completion: 2025-09-25
Conditions
Neoplasms Solid Tumor, Adult Non-Hodgkin Lymphoma Myelodysplastic Syndromes
Interventions
DRUG
No Results Yet
NCT03568552 | COMPLETED | NA
7554 Participants

Patient Decision Aid for Opioid Use Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2020-08-03
Completion: 2024-08-31
Conditions
Opioid Use Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT03527719 | ACTIVE_NOT_RECRUITING | NA
33995 Participants

China Rural Hypertension Control Project

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-05-08
Completion: 2026-01-31
Conditions
Hypertension
Interventions
OTHER
No Results Yet
NCT03505801 | ACTIVE_NOT_RECRUITING
1826 Participants

Confirm Rx Insertable Cardiac Monitor SMART Registry

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2018-04-24
Completion: 2019-09-19
Conditions
Cardiac Arrhythmias Symptoms and Signs Atrial Fibrillation
Interventions
DEVICE
No Results Yet
NCT03501589 | ENROLLING_BY_INVITATION
100 Participants

Molecular Modulation of the Growth Plate

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2013-10-31
Completion: 2026-10-31
Conditions
Growth Plate Injury
No Results Yet
NCT03495232 | ACTIVE_NOT_RECRUITING
700 Participants

Persona Cohort Nordic Multicenter Study

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2016-11-01
Completion: 2029-04-07
Conditions
Knee Arthropathy
Interventions
DEVICE
No Results Yet
NCT03492177 | ACTIVE_NOT_RECRUITING | PHASE2
63 Participants

A Clinical Study of to Confirm the Doses of Selexipag in Children With Pulmonary Arterial Hypertension

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-07-23
Completion: 2022-03-28
Conditions
Pulmonary Arterial Hypertension
Interventions
DRUG
Results Available
NCT03478514 | ACTIVE_NOT_RECRUITING | PHASE2
39 Participants

Phase II Palbociclib +Ibrutinib in Mantle Cell Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-09-11
Completion: 2026-03-30
Conditions
Mantle Cell Lymphoma B Cell Lymphoma
Interventions
DRUG
No Results Yet
NCT03466788 | COMPLETED | NA
51 Participants

Impact of Adjuvant Chemotherapy on the Quality of Life of Patients Treated for Stage II / III Endometrial Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-03-29
Completion: 2019-03-28
Conditions
Endometrial Cancer Chemotherapy Effect Quality of Life
Interventions
OTHER
Results Available
NCT03434392 | RECRUITING | NA
500 Participants

QST Study: Predicting Treatment Response in Chronic Pancreatitis Using Quantitative Sensory Testing

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2017-10-24
Completion: 2026-06-30
Conditions
Chronic Pancreatitis Chronic Pain
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT03407833 | ENROLLING_BY_INVITATION
500 Participants

Physiologic and Functional Adaptations of Insulin Sensitive Tissues

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2018-02-13
Completion: 2028-02-29
Conditions
Diabetes Insulin Resistance Obesity Bariatric Surgery Candidate Roux-en-y Gastric Bypass Liver Diseases
Interventions
OTHER
No Results Yet
NCT03391479 | ACTIVE_NOT_RECRUITING | PHASE2
25 Participants

A Study of Avelumab in Penile Cancer Who Are Unfit for or Have Progressed After Platinum-Based Chemotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-08-15
Completion: 2026-12-31
Conditions
Penile Cancer Advanced Cancer Metastatic Cancer
Interventions
DRUG OTHER
No Results Yet
NCT03388632 | COMPLETED | PHASE1
31 Participants

Recombinant Interleukin-15 in Combination With Checkpoint Inhibitors Nivolumab and Ipilimumab in People With Refractory Cancers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-02-05
Completion: 2024-11-27
Conditions
Metastatic Solid Tumors Treatment-Refractory Cancers
Interventions
DRUG PROCEDURE DIAGNOSTIC_TEST
Results Available
NCT03328130 | TERMINATED | PHASE1/PHASE2
19 Participants

Safety and Efficacy Study in Patients With Retinitis Pigmentosa Due to Mutations in PDE6B Gene

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2017-11-06
Completion: 2025-06-30
Conditions
Retinitis Pigmentosa
Interventions
BIOLOGICAL
No Results Yet
NCT03253692 | COMPLETED
36 Participants

Prospective Multicenter Registry On Radiation Dose Estimates Of Cardiac CT Angiography in Daily Practice in 2017 (PROTECTION VI)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2017-10-03
Completion: 2018-06-30
Conditions
Arteriosclerosis Coronary Artery Disease Coronary Disease Myocardial Ischemia Arterial Occlusive Diseases
No Results Yet
NCT03245593 | ACTIVE_NOT_RECRUITING | NA
300 Participants

Shared Medical Decision Making in the Prophylactic Treatment of Bipolar Disorder

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-04-24
Completion: 2025-12-31
Conditions
Bipolar Disorder
Interventions
OTHER
No Results Yet
NCT03190928 | RECRUITING
200 Participants

Clonal Evolution in Follicular Lymphoma

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2017-07-27
Completion: 2029-01-01
Conditions
Follicular Lymphoma
No Results Yet
NCT03172624 | COMPLETED | PHASE2
64 Participants

Study of Nivolumab Plus Ipilimumab in Patients With Salivary Gland Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2017-05-26
Completion: 2024-12-18
Conditions
Salivary Gland Cancer
Interventions
DRUG
Results Available
NCT03152669 | RECRUITING
3500 Participants

The Extended Salford Lung Study ("Ex-SLS") Data Access Project

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2018-04-15
Completion: 2028-04-30
Conditions
Asthma
No Results Yet
NCT03142841 | COMPLETED | NA
210 Participants

Spanish Intervention for Caregivers of Veterans With Stroke

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-01-01
Completion: 2024-03-04
Conditions
Depression
Interventions
OTHER
Results Available
NCT03079999 | ACTIVE_NOT_RECRUITING | PHASE2
97 Participants

Study of Aspirin in Patients With Vestibular Schwannoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-06-11
Completion: 2026-08-31
Conditions
Vestibular Schwannoma Acoustic Neuroma Neurofibromatosis 2
Interventions
DRUG
No Results Yet
NCT03069469 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
120 Participants

Study of Vimseltinib (DCC-3014) in Patients With Advanced Tumors and Tenosynovial Giant Cell Tumor

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2017-02-16
Completion: 2026-07-31
Conditions
Advanced Malignant Neoplasm Pigmented Villonodular Synovitis Giant Cell Tumor of Tendon Sheath Tenosynovial Giant Cell Tumor Tenosynovial Giant Cell Tumor, Diffuse
Interventions
DRUG
No Results Yet
NCT03009981 | COMPLETED | PHASE3
504 Participants

A Study of Androgen Annihilation in High-Risk Biochemically Relapsed Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2017-03-06
Completion: 2025-06-25
Conditions
Prostate Cancer
Interventions
DRUG
No Results Yet
NCT03006172 | ACTIVE_NOT_RECRUITING | PHASE1
200 Participants

To Evaluate the Safety, Tolerability, and Pharmacokinetics of Inavolisib Single Agent in Participants With Solid Tumors and in Combination With Endocrine and Targeted Therapies in Participants With Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2016-12-13
Completion: 2026-12-31
Conditions
Breast Cancer Solid Tumor
Interventions
DRUG
No Results Yet
NCT02993900 | RECRUITING | NA
54 Participants

Image-Guided Gynecologic Brachytherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2016-12-15
Completion: 2026-12-31
Conditions
Cervical Cancer Uterine Cancer Vaginal Cancer Vulvar Cancer Bladder Cancer
Interventions
DEVICE
No Results Yet
NCT02971501 | ACTIVE_NOT_RECRUITING | PHASE2
7 Participants

Osimertinib With or Without Bevacizumab in Treating Patients With EGFR Positive Non-small Cell Lung Cancer and Brain Metastases

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2018-06-27
Completion: 2025-02-18
Conditions
Metastatic Lung Non-Small Cell Carcinoma Metastatic Malignant Neoplasm in the Brain Stage IV Lung Cancer AJCC v8
Interventions
DRUG BIOLOGICAL PROCEDURE
No Results Yet
NCT02918344 | COMPLETED
196 Participants

Complications From the Use of Calcium Phosphate Paste in Mandibular Lengthening Osteotomies

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2017-03-01
Completion: 2019-12-31
Conditions
Jaw Anomalies Infection
Interventions
OTHER PROCEDURE
No Results Yet
NCT02900183 | WITHDRAWN | PHASE2
0 Participants

Safety, Tolerability and Effect of ARC-AAT Injection on Circulating and Intrahepatic Alpha-1 Antitrypsin Levels

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2016-10-31
Completion: 2016-11-30
Conditions
Alpha-1 Antitrypsin Deficiency
Interventions
DRUG
No Results Yet
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