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Clinical Trials

Showing trials with last updates posted in 2025.

NCT02306720 | ENROLLING_BY_INVITATION
1571 Participants

Registry of Patients With Hypophosphatasia

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2015-01-20
Completion: 2031-12-31
Conditions
Hypophosphatasia (HPP)
No Results Yet
NCT02177578 | ACTIVE_NOT_RECRUITING | PHASE2
60 Participants

Subventricular Zone (SVZ) and Temozolomide in Glioblastoma Multiforme

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2014-07-08
Completion: 2026-06-30
Conditions
Glioblastoma Multiforme
Interventions
DRUG RADIATION
No Results Yet
NCT02115282 | ACTIVE_NOT_RECRUITING | PHASE3
608 Participants

Exemestane With or Without Entinostat in Treating Patients With Recurrent Hormone Receptor-Positive Breast Cancer That is Locally Advanced or Metastatic

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2014-03-29
Completion: 2020-05-05
Conditions
Anatomic Stage III Breast Cancer AJCC v8 Anatomic Stage IV Breast Cancer AJCC v8 Breast Adenocarcinoma HER2/Neu Negative Locally Advanced Breast Carcinoma Metastatic Breast Carcinoma Recurrent Breast Carcinoma
Interventions
PROCEDURE DRUG OTHER
Results Available
NCT02077894 | RECRUITING
1685 Participants

Whole Exome and Whole Genome Sequencing for Genotyping of Inherited and Congenital Eye Conditions

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2014-08-05
Completion: 2029-08-05
Conditions
Genetic Eye Disease
No Results Yet
NCT01984138 | ACTIVE_NOT_RECRUITING | PHASE2
33 Participants

REVIVE: Replens Versus Intra-Vaginal Estrogen for the Treatment of Vaginal Dryness on Aromatase Inhibitor Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2013-09-30
Completion: 2025-06-03
Conditions
Estrogen Receptor Positive Breast Cancer Breast Cancer
Interventions
DRUG
No Results Yet
NCT01850888 | COMPLETED | NA
15 Participants

MIBG for Refractory Neuroblastoma and Pheochromocytoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2013-12-31
Completion: 2025-10-20
Conditions
Relapsed Neuroblastoma Metastatic Pheochromocytoma
Interventions
DRUG PROCEDURE
No Results Yet
NCT01829204 | RECRUITING
550 Participants

Prospective Data Bank Creation to Study Vaginal Conditions

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2013-04-30
Completion: 2027-07-31
Conditions
Vulvodynia Mycoses Bacterial Vaginosis Preterm Labor
No Results Yet
NCT01761422 | ACTIVE_NOT_RECRUITING
40 Participants

Myocardial Inflammation in Systemic Lupus Erythematosus

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2012-07-01
Completion: 2026-11-01
Conditions
SLE
No Results Yet
NCT01653678 | ACTIVE_NOT_RECRUITING | NA
25875 Participants

Vitamin D and Omega-3 Hypertension Trial (VITAL Hypertension)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2011-11-30
Completion: 2025-11-30
Conditions
Hypertension
Interventions
DIETARY_SUPPLEMENT DRUG
No Results Yet
NCT01571531 | RECRUITING
8000 Participants

European Multicentre Study of Human Spinal Cord Injury

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2004-04-30
Completion: 2026-08-31
Conditions
Spinal Cord Injury
No Results Yet
NCT01483664 | ACTIVE_NOT_RECRUITING
314 Participants

Communication Skills Intervention to Promote Transition Into Survivorship

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2011-11-30
Completion: 2026-11-30
Conditions
Hodgkin's Lymphoma Diffuse Large B-cell Lymphoma
No Results Yet
NCT01451502 | RECRUITING | NA
250 Participants

Infusion of Cell Populations From Unlicensed Umbilical Cord Blood Units

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2011-10-20
Completion: 2026-04-30
Conditions
Lymphatic Diseases Hematopoietic Malignancy
Interventions
BIOLOGICAL
No Results Yet
NCT01371630 | RECRUITING | PHASE1/PHASE2
276 Participants

Inotuzumab Ozogamicin and Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2011-08-26
Completion: 2027-12-25
Conditions
B Acute Lymphoblastic Leukemia With t(9;22)(q34.1;q11.2); BCR-ABL1 B Acute Lymphoblastic Leukemia, Philadelphia Chromosome Negative Burkitt-Like Lymphoma With 11q Aberration High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements High Grade B-Cell Lymphoma, Not Otherwise Specified Recurrent B Acute Lymphoblastic Leukemia Recurrent Burkitt Lymphoma Refractory B Acute Lymphoblastic Leukemia Refractory Burkitt Lymphoma
Interventions
BIOLOGICAL DRUG OTHER
No Results Yet
NCT01257646 | COMPLETED | NA
20 Participants

Observation of the Gait Cycle in Patients With Hemiplegia in Order to Improve the Triggering of Functional Electrical Stimulation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2011-05-31
Completion: 2013-07-31
Conditions
Stroke
Interventions
OTHER
No Results Yet
NCT01048281 | RECRUITING
100 Participants

Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2002-08-31
Completion: 2099-01-31
Conditions
Stomach Cancer Gastro-Esophageal(GE) Junction Cancer Gastric (Stomach) Cancer Esophageal Cancer Gastrointestinal Stromal Tumor (GIST)
Interventions
PROCEDURE
No Results Yet
NCT01037530 | COMPLETED | PHASE4
33 Participants

Clinical and Cost Effectiveness of ACE Inhibitor, Ramipril, in Intermittent Claudicants

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2010-12-31
Completion: 2012-12-31
Conditions
Intermittent Claudicants
Interventions
DRUG
Results Available
NCT01000077 | ENROLLING_BY_INVITATION
1000 Participants

Establishment of Cell Culture Systems From Discarded Operating Room Tissue

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2009-02-28
Completion: 2035-12-31
Conditions
Surgery
No Results Yet
NCT00983463 | ENROLLING_BY_INVITATION
45 Participants

Abundance and Distribution of Lipids and Proteins in Nonalcoholic Fatty Liver Disease (NAFLD)

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2009-10-31
Completion: 2026-11-30
Conditions
Nonalcoholic Fatty Liver Disease
No Results Yet
NCT00700414 | RECRUITING
9999 Participants

International Pediatric Adrenocortical Tumor Registry

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2001-10-01
Completion: 2040-12-31
Conditions
Adrenocortical Tumor
No Results Yet
NCT00678912 | COMPLETED | NA
30 Participants

Weaning Children From Mechanical Ventilation:Computer-driven System Versus Usual Care

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2007-09-30
Completion: 2009-06-30
Conditions
Respiratory Failure
Interventions
DEVICE
No Results Yet
NCT00666016 | COMPLETED | PHASE2
22 Participants

Exploratory Study to Assess the Short Term Effect on Liver Enzymes and the Safety of TRO19622 in Patients With Non-Alcoholic Steatohepatitis (NASH)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2008-04-15
Completion: 2009-02-05
Conditions
Non-Alcoholic Steatohepatitis (NASH)
Interventions
DRUG
No Results Yet
NCT00540774 | SUSPENDED | NA
2500 Participants

Optical Sensor for Photodynamic Detection of Oral Pathology

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2003-04-30
Completion: 2025-06-03
Conditions
Mouth Diseases
Interventions
DEVICE
No Results Yet
NCT00186147 | ENROLLING_BY_INVITATION
9999 Participants

Bone Marrow Grafting for Leukemia and Lymphoma

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 1988-03-31
Completion: 2069-12-31
Conditions
Leukemia Lymphoma Hematologic Diseases
Interventions
PROCEDURE
No Results Yet
NCT00117286 | COMPLETED | PHASE2/PHASE3
57 Participants

Extension Study Investigating the Long-Term Safety of Degarelix One-Month Depots in Patients With Prostate Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-18
Start Date: 2005-03-31
Completion: 2009-09-30
Conditions
Prostate Cancer
Interventions
DRUG
Results Available
NCT00027326 | ENROLLING_BY_INVITATION
1000 Participants

Collection of Blood and Urine From Patients Undergoing Radiation Therapy

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 2001-12-02
Conditions
Carcinoma Cancer Tumor
No Results Yet
NCT00001351 | ENROLLING_BY_INVITATION
500 Participants

Evaluation and Long-Term Follow-up of Patients With Inflammatory Disorders

Study Type: OBSERVATIONAL
Last Updated: 2025-12-18
Start Date: 1993-06-01
Conditions
Inflammation
No Results Yet
NCT07290075 | COMPLETED
101 Participants

The Relationship Between Olfactory and Gustatory Senses, Hedonic Hunger, and Diet Quality After Bariatric Surgery

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2024-01-01
Completion: 2024-11-30
Conditions
Obesity Taste Disorders Smell Disorder
Interventions
OTHER
No Results Yet
NCT07290062 | NOT_YET_RECRUITING | PHASE1
23 Participants

A Study to Investigate the Safety and Pharmacodynamics of a Single Intrathecal Injection (IT) of INS1202 in Participants With Amyotrophic Lateral Sclerosis (ALS)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-12-31
Completion: 2030-03-31
Conditions
Amyotrophic Lateral Sclerosis
Interventions
GENETIC
No Results Yet
NCT07290049 | RECRUITING | NA
46 Participants

Postoperative Pain After Pulpotomy in Children Using Calcium Silicate Cements With and Without Laser Therapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-04-24
Completion: 2025-12-25
Conditions
Symptomatic Irreversible Pulpitis Symptomatic Irreversible Pulpitis (SIP)
Interventions
DEVICE
No Results Yet
NCT07290023 | COMPLETED
126 Participants

Oral and Gut Microbiota in Individuals With Serrated Polyposis Syndrome.

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2021-01-11
Completion: 2023-12-31
Conditions
Colorectal Cancer Serrated Polyposis Syndrome Intestinal Microbiota
No Results Yet
NCT07290010 | RECRUITING | PHASE2
25 Participants

The Efficacy and Safety of Iparomlimab and Tuvonralimab Injection Combined With Chemotherapy as the First-line Treatment for Esophageal Squamous Cell Carcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-09-26
Completion: 2026-12-31
Conditions
Esophageal Squamous Cell Carcinoma (ESCC)
Interventions
DRUG
No Results Yet
NCT07289997 | RECRUITING | PHASE2
39 Participants

Iparomlimab and Tuvonralimab Combined With Apatinib and Irinotecan Hydrochloride for the Treatment of Advanced Alpha-fetoprotein-producing Gastric Cancer (AFPGC)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-09-28
Completion: 2027-09-30
Conditions
AFP Gastric or Gastroesophageal Junction Adenocarcinoma PD-1/CTLA-4 AFPGC Immunotherapy
Interventions
DRUG
No Results Yet
NCT07289984 | NOT_YET_RECRUITING | NA
50 Participants

Correlation Between Diagnostic Nerve Block Response and Cryoneurolysis Outcome in Chronic Musculoskeletal Disorders and Spasticity

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-02-01
Completion: 2030-05-01
Conditions
Spasticity Chronic Musculoskeletal Pain Cryo Analgesia Cryoablation
Interventions
PROCEDURE
No Results Yet
NCT07289958 | NOT_YET_RECRUITING | NA
52 Participants

Effects of Respiratory Muscle Training in Post-bariatric Surgery Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-01-05
Completion: 2027-06-30
Conditions
Bariatric Surgery
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT07289945 | COMPLETED | PHASE3
81 Participants

Effects of Sevoflurane vs Desflurane on Early Recovery and Cognitive Function in Elderly Patients Undergoing Scheduled Non-Cardiac Surgery

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-09-15
Completion: 2025-04-15
Conditions
Early Recovery in Elderly Patients Cognitive Function
Interventions
DRUG
No Results Yet
NCT07289932 | ENROLLING_BY_INVITATION | NA
38 Participants

"Clinical Evaluation of Self-Assembling Peptides Versus Tri-Calcium Phosphate Based Varnish in Treatment of White Spot Lesions; Split-Mouth Randomized Clinical Trial"

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-02-20
Completion: 2024-11-20
Conditions
White Spot Lesions
Interventions
OTHER
No Results Yet
NCT07289919 | ACTIVE_NOT_RECRUITING | NA
15 Participants

Exploring Sustainable Alternatives to Marine Oils With Echium and Ahiflower Oils

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-05-26
Completion: 2026-03-05
Conditions
Cardiovascular (CV) Risk Atheroscleroses Inflamation Omega 3 Fatty Acids Supplement
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT07289906 | ACTIVE_NOT_RECRUITING
40 Participants

Measurement of Mass Change in Serum Albumin Compared to Serum Lactic Acid as Predictive Tool for Sepsis Prognosis in Non Surgical ICU Patients

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2025-09-28
Completion: 2026-09-28
Conditions
Prognosis Prediction of Sepsis in Icu Patients
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT07289893 | RECRUITING | NA
38 Participants

Investigation of the Effects of Kettlebell Training

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-11-25
Completion: 2025-12-31
Conditions
Shoulder Pain Rotator Cuff Injuries
Interventions
OTHER
No Results Yet
NCT07289867 | COMPLETED | NA
40 Participants

Nutritional Effects of Supplementing Nonagenarians With a Supplement Based on a Fruit From the Cerrado: Buriti

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2024-05-01
Completion: 2024-08-26
Conditions
Malnutrition in the Elderly
Interventions
DIETARY_SUPPLEMENT
No Results Yet
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