Clinical Trials
Showing trials with last updates posted in 2025.
60
Participants
STREAM-2: Second-line Treatment With REgorafenib in Advanced RAS-Mutant Colorectal Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-10-16
Completion:
2026-10-31
Conditions
Colorectal Cancer Metastatic
Interventions
DRUG
No Results Yet
84
Participants
Simvastatin Efficacy in ARID1A Mutated Advanced gastroESophageal Carcinoma Treated With Immunotherapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-12-31
Completion:
2027-05-31
Conditions
Advanced or Metastatic Gastrooesophageal Carcinoma
Interventions
DRUG
No Results Yet
300
Participants
A Study of NT 201 in Adults With Moderate to Severe Platysma Prominence in Europe (PLATINUM EU)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-10-01
Completion:
2027-01-31
Conditions
Neuromuscular Agents
Peripheral Nervous System Agents
Physiological Effects of Drugs
Acetylcholine Release Inhibitors
Membrane Transport Modulators
Molecular Mechanisms of Pharmacological Action
Cholinergic Agents
Neurotransmitter Agents
incobotulinumtoxinA
Botulinum Toxins, Type A
Interventions
DRUG
No Results Yet
132
Participants
Comparative Study on the Post-operative Pain and Other Outcomes of Mesh Fixation With Prolene vs Vicryl vs Skin Staples in Lichtenstein Inguinal Hernia Repair.
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-17
Start Date:
2025-12-29
Completion:
2026-01-29
Conditions
Inguinal Hernia
Interventions
PROCEDURE
No Results Yet
298
Participants
EDX110 Randomized Control Trial for Treatment of DFUs
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-10-30
Completion:
2026-12-01
Conditions
Wound Heal
Diabetic Foot Ulcer
Interventions
DEVICE
No Results Yet
340
Participants
Electroacupuncture Treatment for Post-stroke Cognitive Impairment
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-10-05
Completion:
2026-12-30
Conditions
Post-Stroke Cognitive Impairment (PSCI)
Interventions
OTHER
No Results Yet
24
Participants
Clinical Trial on Rapid Immune Modulating Effects
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-09-28
Completion:
2026-02-01
Conditions
Immune Surveillance
Interventions
DIETARY_SUPPLEMENT
No Results Yet
80
Participants
Study of Safety/Feasibility of a Hybrid Model of Tertiary and Community Delivery of Hepatic Artery Infusion Chemotherapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-12-31
Completion:
2028-02-29
Conditions
Colorectal Cancer Metastatic
Intrahepatic Cholangiocarcinoma
Interventions
DEVICE
PROCEDURE
DRUG
No Results Yet
735
Participants
Individualised Endometrial Cancer Risk Stratification by Bayesian Prediction Model (ENDORISK), Optimizing Clinical Implementation
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-10-23
Completion:
2027-10-16
Conditions
Endometrial Cancer
Interventions
DIAGNOSTIC_TEST
No Results Yet
130
Participants
OCT-Guided Stent Optimization for Short-Duration Dual Antiplatelet Therapy in Stable Angina
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-09-30
Completion:
2029-09-30
Conditions
Stable Angina
Coronary Artery Disease
Interventions
DRUG
DEVICE
No Results Yet
200
Participants
An Extension Trial to Test if TEV-56286 is Effective in Relieving Multiple System Atrophy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-09-30
Completion:
2029-05-03
Conditions
Multiple System Atrophy
Interventions
DRUG
No Results Yet
766
Participants
Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-12-10
Completion:
2031-12-31
Conditions
Glioblastoma
Interventions
DEVICE
RADIATION
DRUG
No Results Yet
20
Participants
Glymphatic Function TMS Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-01-31
Completion:
2026-07-31
Conditions
Mild Cognitive Impairment
Interventions
DEVICE
No Results Yet
21
Participants
Kinesiophobia vs. Task-Specific Fear: Defining Movement-Related Fear in ACL Reconstruction Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-01-01
Completion:
2026-12-01
Conditions
ACL Reconstruction
Interventions
OTHER
No Results Yet
164
Participants
A Prospective Controlled Study to Evaluate the Safety and Effectiveness of Thermage® FLX Radiofrequency Treatment
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-10-31
Completion:
2026-06-30
Conditions
Lax Skin
Lines Skin
Wrinkle
Interventions
DEVICE
No Results Yet
10
Participants
Safety and Tolerability of Subretinally Injected OPGx-BEST1 in Patients With Best Vitelliform Macular Dystrophy (BVMD) or Autosomal-Recessive Bestrophinopathy (ARB)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-09-25
Completion:
2030-08-31
Conditions
ARB
BVMD
Autosomal-Dominant Bestrophinopathy
Best Vitelliform Macular Dystrophy
Interventions
GENETIC
No Results Yet
100
Participants
Point-of-Care Ultrasound (PoCUS) Teleeducation Curriculum for Hospital-at-home Care
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-04-01
Completion:
2027-10-30
Conditions
Educational Problems
Interventions
OTHER
No Results Yet
672
Participants
Sleep and Blankets
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-10-15
Completion:
2026-12-15
Conditions
Sleep Problems
Insomnia
Interventions
DEVICE
No Results Yet
158
Participants
A Study of CM336 in Patients With Relapsed or Refractory Autoimmune Cytopenia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-11-18
Completion:
2027-11-18
Conditions
Autoimmune Cytopenia
Immune Thrombocytopenia (ITP)
Autoimmune Hemolytic Anemia
Evans Syndrome
Interventions
BIOLOGICAL
No Results Yet
320
Participants
Remote Evaluation and Alerting for Collaborative Health (REACH) in Depression
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-01-01
Completion:
2029-11-01
Conditions
Depression
Major Depressive Disorder
Interventions
OTHER
No Results Yet
100
Participants
Speech Production Enhancement Using Augmentative Communication for Kids
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-01-31
Completion:
2029-02-28
Conditions
Cerebral Palsy (CP)
Intelligibility, Speech
Augmentative and Alternative Communication
Interventions
BEHAVIORAL
No Results Yet
50
Participants
HC010 in First-line PD-L1 Positive Advanced NSCLC Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-12-09
Completion:
2026-12-30
Conditions
NSCLC
Interventions
DRUG
No Results Yet
42
Participants
The Effect of Video Game-Based Exercise Training in Patients With Interstitial Lung Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-01-25
Completion:
2026-09-25
Conditions
Interstitial Lung Disease
Interventions
BEHAVIORAL
No Results Yet
15
Participants
Electrostimulation Study for Ocular Graft vs. Host Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-11-30
Completion:
2028-11-30
Conditions
Chronic Ocular Graft-versus-host Disease
Interventions
DEVICE
No Results Yet
130
Participants
Evaluating the Efficacy of OCM™ (Omeza® Complete Matrix) in the Treatment of Diabetic Foot Ulcers
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-12-04
Completion:
2026-12-01
Conditions
Diabetic Foot Ulcer
Interventions
DEVICE
OTHER
No Results Yet
75
Participants
Leuprolide and Goserelin for Ovarian Function Suppression in Pre- or Peri-menopausal Women With Breast Cancer, OFS Trial
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-01-01
Completion:
2028-01-01
Conditions
Anatomic Stage I Breast Cancer AJCC v8
Anatomic Stage II Breast Cancer AJCC v8
Anatomic Stage III Breast Cancer AJCC v8
Anatomic Stage IV Breast Cancer AJCC v8
Metastatic Breast Carcinoma
Interventions
PROCEDURE
OTHER
DRUG
No Results Yet
128
Participants
Exploring the Effect of Aromatherapy
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-10-15
Completion:
2026-09-01
Conditions
Anxiety
Labor Pain
Nausea and Vomiting
Interventions
OTHER
No Results Yet
2
Participants
First-in-Human Safety Study for Fractomerâ„¢ Biomatrix
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-08-11
Completion:
2025-10-22
Conditions
Soft Tissue
Soft Tissue Defects
Subcutaneous Injection
Interventions
DEVICE
No Results Yet
107
Participants
Alpha-Emitting Radionuclide or Beta-Emitting Radionuclide With Metastasis-Directed Stereotactic Body Radiotherapy for the Treatment of Recurrent, Oligometastatic Prostate Adenocarcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-12-12
Completion:
2030-10-31
Conditions
Oligometastatic Prostate Adenocarcinoma
Recurrent Prostate Adenocarcinoma
Interventions
DRUG
PROCEDURE
OTHER
RADIATION
No Results Yet
500
Participants
Radicle Clarity: A Study Assessing the Impact of Health and Wellness Products on Cognitive Function and Related Health Outcomes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-08-21
Completion:
2025-11-14
Conditions
Cognitive Function
Interventions
DIETARY_SUPPLEMENT
No Results Yet
258
Participants
A Study to Assess Adverse Events, Change in Disease Activity, and How Oral Emraclidine Moves Through the Body in Adult Participants With Schizophrenia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-08-04
Completion:
2028-02-29
Conditions
Schizophrenia
Interventions
DRUG
No Results Yet
640
Participants
Placental Risk Assessment to CusTomize Individualized Pregnancy Care and Evaluation
Study Type:
OBSERVATIONAL
Last Updated:
2025-12-17
Start Date:
2025-09-18
Completion:
2029-06-30
Conditions
Stillbirth
Placental Insufficiency
Interventions
OTHER
No Results Yet
150
Participants
A Study to Evaluate Atumelnant in Adults With Congenital Adrenal Hyperplasia
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-12-11
Completion:
2027-05-31
Conditions
Congenital Adrenal Hyperplasia
Classic Congenital Adrenal Hyperplasia
Interventions
DRUG
No Results Yet
12
Participants
Enhancing Slow Wave Sleep in Depression
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-01-31
Completion:
2026-12-31
Conditions
Depression - Major Depressive Disorder
Interventions
DEVICE
No Results Yet
60
Participants
Supraphysiologic Testosterone Priming Induces Darolutamide Extended Response
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-02-20
Completion:
2030-06-01
Conditions
Metastatic Castration-resistant Prostate Cancer
Interventions
DRUG
No Results Yet
255
Participants
ADL+2.0: Intervention for Prevention of Cognitive Decline in Community-dwelling Older Adults
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-05-08
Completion:
2029-08-30
Conditions
Cognitive Decline
Interventions
OTHER
No Results Yet
100
Participants
Vaped Phenanthrene
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-02-01
Completion:
2027-09-01
Conditions
Former Smoker
Non-Smoker
Interventions
OTHER
No Results Yet
191
Participants
Patient Satisfaction With AI Scribes
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-08-11
Completion:
2025-10-21
Conditions
AI (Artificial Intelligence)
Patient Satisfaction With AI in Doctors Consultations
Interventions
OTHER
No Results Yet
405
Participants
A Phase I/II Study on Safety AND Immunogenicity of AZD4117 and AZD5315 Vaccines (PANDA)
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2025-09-04
Completion:
2026-01-20
Conditions
Influenza A
Interventions
BIOLOGICAL
OTHER
No Results Yet
150
Participants
A Clinical Trial to Investigate the Efficacy and Safety of GenLabs' Social Skin on Improving Acne Symptoms and Skin Repair Among Healthy Adults
Study Type:
INTERVENTIONAL
Last Updated:
2025-12-17
Start Date:
2026-01-31
Completion:
2026-04-30
Conditions
Acne
Interventions
OTHER
No Results Yet
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