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Clinical Trials

Showing trials with last updates posted in 2025.

NCT07222072 | RECRUITING | PHASE4
120 Participants

Methadone to Reduce Chronic Opioid Use After Major Spine Surgery: The MEND Pilot Feasibility Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-11-15
Completion: 2027-10-31
Conditions
Post Operative Pain Spinal Surgery
Interventions
DRUG
No Results Yet
NCT07222020 | RECRUITING | PHASE1
24 Participants

Phase 1 Study of Intravaginal KB15A

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-01-01
Completion: 2026-09-01
Conditions
Healthy Subjects
Interventions
DRUG
No Results Yet
NCT07221552 | NOT_YET_RECRUITING | NA
16 Participants

Evaluation of the PPAL

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-01-31
Completion: 2026-07-31
Conditions
Age Problems
Interventions
DEVICE
No Results Yet
NCT07221500 | RECRUITING | PHASE2
100 Participants

A Study of NX-5948 in Adults With CLL/SLL Previously Treated With a Bruton's Tyrosine Kinase Inhibitor and a B-cell Lymphoma-2 Inhibitor (DAYBreak CLL-201)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-10-15
Completion: 2028-01-31
Conditions
Chronic Lymphocytic Leukemia (CLL) Small Lymphocytic Lymphoma (SLL)
Interventions
DRUG
No Results Yet
NCT07220616 | NOT_YET_RECRUITING | PHASE1/PHASE2
420 Participants

A First-in-Human Trial of DS3790a in Participants With Hematological Malignancies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-01-15
Completion: 2030-11-30
Conditions
Hematological Malignancies
Interventions
DRUG
No Results Yet
NCT07219511 | RECRUITING | PHASE1
42 Participants

A Safety, Tolerability, and Biomarker Trial of VS-041 in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-11-04
Completion: 2026-06-30
Conditions
Heart Heart Failure With Preserved Ejection Fraction (HFPEF)
Interventions
DRUG OTHER
No Results Yet
NCT07218588 | RECRUITING | NA
50 Participants

Sanctuary Farm Prescription in Adolescents

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-11-20
Completion: 2026-03-30
Conditions
Obesity &Amp; Overweight Adolescence
Interventions
OTHER
No Results Yet
NCT07216105 | RECRUITING | PHASE1
113 Participants

FT836 With or Without Chemotherapy and/or Monoclonal Antibodies, in Participants With Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-11-04
Completion: 2028-01-31
Conditions
Non-Small Cell Lung Cancer Colorectal Cancer Breast Cancer Ovarian Cancer Endometrial Carcinoma Head and Neck Squamous Cell Carcinoma
Interventions
DRUG
No Results Yet
NCT07214740 | COMPLETED | PHASE3
44 Participants

Study to Evaluate a Pegcetacoplan (Syfovre®) Prefilled Syringe

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-10-24
Completion: 2025-12-12
Conditions
Geographic Atrophy Secondary to Age-related Macular Degeneration
Interventions
DRUG
No Results Yet
NCT07213830 | RECRUITING | PHASE1/PHASE2
102 Participants

A Study to Assess the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Immunogenicity and Anti-tumour Activity of IPN01203 in Adults With Locally Advanced or Metastatic Solid Tumours Exposed to Immune Checkpoint Inhibitor Therapies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-01-31
Completion: 2032-07-14
Conditions
Advanced Solid Tumor Metastatic Solid Tumor
Interventions
BIOLOGICAL
No Results Yet
NCT07213570 | RECRUITING | PHASE2
60 Participants

STREAM-2: Second-line Treatment With REgorafenib in Advanced RAS-Mutant Colorectal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-10-16
Completion: 2026-10-31
Conditions
Colorectal Cancer Metastatic
Interventions
DRUG
No Results Yet
NCT07213557 | NOT_YET_RECRUITING | PHASE2
84 Participants

Simvastatin Efficacy in ARID1A Mutated Advanced gastroESophageal Carcinoma Treated With Immunotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-12-31
Completion: 2027-05-31
Conditions
Advanced or Metastatic Gastrooesophageal Carcinoma
Interventions
DRUG
No Results Yet
NCT07210463 | RECRUITING | PHASE3
300 Participants

A Study of NT 201 in Adults With Moderate to Severe Platysma Prominence in Europe (PLATINUM EU)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-10-01
Completion: 2027-01-31
Conditions
Neuromuscular Agents Peripheral Nervous System Agents Physiological Effects of Drugs Acetylcholine Release Inhibitors Membrane Transport Modulators Molecular Mechanisms of Pharmacological Action Cholinergic Agents Neurotransmitter Agents incobotulinumtoxinA Botulinum Toxins, Type A
Interventions
DRUG
No Results Yet
NCT07210424 | NOT_YET_RECRUITING
132 Participants

Comparative Study on the Post-operative Pain and Other Outcomes of Mesh Fixation With Prolene vs Vicryl vs Skin Staples in Lichtenstein Inguinal Hernia Repair.

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2025-12-29
Completion: 2026-01-29
Conditions
Inguinal Hernia
Interventions
PROCEDURE
No Results Yet
NCT07209358 | RECRUITING | NA
298 Participants

EDX110 Randomized Control Trial for Treatment of DFUs

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-10-30
Completion: 2026-12-01
Conditions
Wound Heal Diabetic Foot Ulcer
Interventions
DEVICE
No Results Yet
NCT07208019 | RECRUITING | NA
340 Participants

Electroacupuncture Treatment for Post-stroke Cognitive Impairment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-10-05
Completion: 2026-12-30
Conditions
Post-Stroke Cognitive Impairment (PSCI)
Interventions
OTHER
No Results Yet
NCT07206407 | RECRUITING | NA
24 Participants

Clinical Trial on Rapid Immune Modulating Effects

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-09-28
Completion: 2026-02-01
Conditions
Immune Surveillance
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT07201519 | NOT_YET_RECRUITING | PHASE2
80 Participants

Study of Safety/Feasibility of a Hybrid Model of Tertiary and Community Delivery of Hepatic Artery Infusion Chemotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-12-31
Completion: 2028-02-29
Conditions
Colorectal Cancer Metastatic Intrahepatic Cholangiocarcinoma
Interventions
DEVICE PROCEDURE DRUG
No Results Yet
NCT07200466 | RECRUITING | NA
735 Participants

Individualised Endometrial Cancer Risk Stratification by Bayesian Prediction Model (ENDORISK), Optimizing Clinical Implementation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-10-23
Completion: 2027-10-16
Conditions
Endometrial Cancer
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT07198529 | RECRUITING | NA
130 Participants

OCT-Guided Stent Optimization for Short-Duration Dual Antiplatelet Therapy in Stable Angina

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-09-30
Completion: 2029-09-30
Conditions
Stable Angina Coronary Artery Disease
Interventions
DRUG DEVICE
No Results Yet
NCT07197866 | RECRUITING | PHASE2
200 Participants

An Extension Trial to Test if TEV-56286 is Effective in Relieving Multiple System Atrophy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-09-30
Completion: 2029-05-03
Conditions
Multiple System Atrophy
Interventions
DRUG
No Results Yet
NCT07195591 | RECRUITING | PHASE3
766 Participants

Beginning Radiation Immediately With GammaTile at GBM Excision Versus Standard of Care

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-12-10
Completion: 2031-12-31
Conditions
Glioblastoma
Interventions
DEVICE RADIATION DRUG
No Results Yet
NCT07192913 | NOT_YET_RECRUITING | PHASE2
20 Participants

Glymphatic Function TMS Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-01-31
Completion: 2026-07-31
Conditions
Mild Cognitive Impairment
Interventions
DEVICE
No Results Yet
NCT07190456 | RECRUITING | NA
21 Participants

Kinesiophobia vs. Task-Specific Fear: Defining Movement-Related Fear in ACL Reconstruction Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-01-01
Completion: 2026-12-01
Conditions
ACL Reconstruction
Interventions
OTHER
No Results Yet
NCT07187297 | RECRUITING | NA
164 Participants

A Prospective Controlled Study to Evaluate the Safety and Effectiveness of Thermage® FLX Radiofrequency Treatment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-10-31
Completion: 2026-06-30
Conditions
Lax Skin Lines Skin Wrinkle
Interventions
DEVICE
No Results Yet
NCT07185256 | RECRUITING | PHASE1/PHASE2
10 Participants

Safety and Tolerability of Subretinally Injected OPGx-BEST1 in Patients With Best Vitelliform Macular Dystrophy (BVMD) or Autosomal-Recessive Bestrophinopathy (ARB)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-09-25
Completion: 2030-08-31
Conditions
ARB BVMD Autosomal-Dominant Bestrophinopathy Best Vitelliform Macular Dystrophy
Interventions
GENETIC
No Results Yet
NCT07182162 | NOT_YET_RECRUITING | NA
100 Participants

Point-of-Care Ultrasound (PoCUS) Teleeducation Curriculum for Hospital-at-home Care

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-04-01
Completion: 2027-10-30
Conditions
Educational Problems
Interventions
OTHER
No Results Yet
NCT07181577 | RECRUITING | NA
672 Participants

Sleep and Blankets

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-10-15
Completion: 2026-12-15
Conditions
Sleep Problems Insomnia
Interventions
DEVICE
No Results Yet
NCT07175493 | RECRUITING | PHASE1/PHASE2
158 Participants

A Study of CM336 in Patients With Relapsed or Refractory Autoimmune Cytopenia

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-11-18
Completion: 2027-11-18
Conditions
Autoimmune Cytopenia Immune Thrombocytopenia (ITP) Autoimmune Hemolytic Anemia Evans Syndrome
Interventions
BIOLOGICAL
No Results Yet
NCT07174557 | NOT_YET_RECRUITING | NA
320 Participants

Remote Evaluation and Alerting for Collaborative Health (REACH) in Depression

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-01-01
Completion: 2029-11-01
Conditions
Depression Major Depressive Disorder
Interventions
OTHER
No Results Yet
NCT07173049 | NOT_YET_RECRUITING | NA
100 Participants

Speech Production Enhancement Using Augmentative Communication for Kids

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-01-31
Completion: 2029-02-28
Conditions
Cerebral Palsy (CP) Intelligibility, Speech Augmentative and Alternative Communication
Interventions
BEHAVIORAL
No Results Yet
NCT07169552 | RECRUITING | PHASE2
50 Participants

HC010 in First-line PD-L1 Positive Advanced NSCLC Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-12-09
Completion: 2026-12-30
Conditions
NSCLC
Interventions
DRUG
No Results Yet
NCT07167238 | NOT_YET_RECRUITING | NA
42 Participants

The Effect of Video Game-Based Exercise Training in Patients With Interstitial Lung Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-01-25
Completion: 2026-09-25
Conditions
Interstitial Lung Disease
Interventions
BEHAVIORAL
No Results Yet
NCT07166848 | RECRUITING | NA
15 Participants

Electrostimulation Study for Ocular Graft vs. Host Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-11-30
Completion: 2028-11-30
Conditions
Chronic Ocular Graft-versus-host Disease
Interventions
DEVICE
No Results Yet
NCT07161830 | RECRUITING | NA
130 Participants

Evaluating the Efficacy of OCM™ (Omeza® Complete Matrix) in the Treatment of Diabetic Foot Ulcers

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-12-04
Completion: 2026-12-01
Conditions
Diabetic Foot Ulcer
Interventions
DEVICE OTHER
No Results Yet
NCT07158021 | RECRUITING | PHASE2
75 Participants

Leuprolide and Goserelin for Ovarian Function Suppression in Pre- or Peri-menopausal Women With Breast Cancer, OFS Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2026-01-01
Completion: 2028-01-01
Conditions
Anatomic Stage I Breast Cancer AJCC v8 Anatomic Stage II Breast Cancer AJCC v8 Anatomic Stage III Breast Cancer AJCC v8 Anatomic Stage IV Breast Cancer AJCC v8 Metastatic Breast Carcinoma
Interventions
PROCEDURE OTHER DRUG
No Results Yet
NCT07155876 | ENROLLING_BY_INVITATION | NA
128 Participants

Exploring the Effect of Aromatherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-10-15
Completion: 2026-09-01
Conditions
Anxiety Labor Pain Nausea and Vomiting
Interventions
OTHER
No Results Yet
NCT07151638 | COMPLETED | NA
2 Participants

First-in-Human Safety Study for Fractomer™ Biomatrix

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-08-11
Completion: 2025-10-22
Conditions
Soft Tissue Soft Tissue Defects Subcutaneous Injection
Interventions
DEVICE
No Results Yet
NCT07150715 | RECRUITING | PHASE2
107 Participants

Alpha-Emitting Radionuclide or Beta-Emitting Radionuclide With Metastasis-Directed Stereotactic Body Radiotherapy for the Treatment of Recurrent, Oligometastatic Prostate Adenocarcinoma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-12-12
Completion: 2030-10-31
Conditions
Oligometastatic Prostate Adenocarcinoma Recurrent Prostate Adenocarcinoma
Interventions
DRUG PROCEDURE OTHER RADIATION
No Results Yet
NCT07148986 | COMPLETED | NA
500 Participants

Radicle Clarity: A Study Assessing the Impact of Health and Wellness Products on Cognitive Function and Related Health Outcomes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-08-21
Completion: 2025-11-14
Conditions
Cognitive Function
Interventions
DIETARY_SUPPLEMENT
No Results Yet
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