Clinical Trials

Showing trials with last updates posted in 2025.

NCT05846594 | COMPLETED | NA
463 Participants

A Study to Evaluate the Impact of Liquid Biopsy in Participants With a Clinical Diagnosis of Advanced Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-09-14
Completion: 2024-09-06
Conditions
Metastatic Lung Cancer Metastatic Gastrointestinal Cancer
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT05844449 | ENROLLING_BY_INVITATION | PHASE3
174 Participants

Evaluation of Long-Term Safety and Efficacy of Vanzacaftor/Tezacaftor/Deutivacaftor in Cystic Fibrosis Participants 1 Year of Age and Older

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-08-11
Completion: 2029-07-30
Conditions
Cystic Fibrosis
Interventions
DRUG
No Results Yet
NCT05843175 | COMPLETED | NA
20 Participants

Maternal ExeRcIse Timing to Optimise Postprandial Glucose in Type 1 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-06-22
Completion: 2025-09-30
Conditions
Pregnancy in Diabetic Type 1 Diabetes
Interventions
OTHER
No Results Yet
NCT05832151 | COMPLETED | PHASE2
382 Participants

A Study to Evaluate the Efficacy and Safety of CIN-102 (Deudomperidone) in Adults With Diabetic Gastroparesis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-03-27
Completion: 2025-11-14
Conditions
Diabetic Gastroparesis
Interventions
DRUG
No Results Yet
NCT05831189 | COMPLETED | PHASE3
41 Participants

A Multi-center, Single-arm Trial Exploring the Safety and Clinical Effectiveness of RBX2660 Administered by Colonoscopy to Adults With Recurrent Clostridioides Difficile Infection

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-04-21
Completion: 2025-01-17
Conditions
Clostridium Difficile Infection Recurrence
Interventions
DRUG
No Results Yet
NCT05818189 | RECRUITING | NA
60 Participants

Cortical Correlates of Gait in Parkinson's Disease: Impact of Medication and Cueing

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-01-15
Completion: 2027-10-01
Conditions
Parkinson Disease
Interventions
DEVICE
No Results Yet
NCT05805384 | RECRUITING | NA
60 Participants

Evaluating a Noise Reduction Algorithm With Cochlear Implant Users

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-03-01
Completion: 2027-03-01
Conditions
Hearing Impairment
Interventions
DEVICE
No Results Yet
NCT05802940 | ACTIVE_NOT_RECRUITING | NA
839 Participants

Low Dose Aspirin Alerts in High-Risk Pregnancies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-06-19
Completion: 2025-10-09
Conditions
Preeclampsia Aspirin Clinical Decision Support Systems Economics, Behavioral
Interventions
BEHAVIORAL
No Results Yet
NCT05797961 | COMPLETED | NA
100 Participants

HIV Self-testing With Online Supervision for Vietnamese MSM

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-05-01
Completion: 2024-12-25
Conditions
HIV
Interventions
BEHAVIORAL OTHER
NCT05797168 | RECRUITING | PHASE1/PHASE2
506 Participants

Phase I/IIa Study of AZD5335 as Monotherapy and Combination Therapy in Participants With Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-06-05
Completion: 2028-01-06
Conditions
Ovarian Cancer Lung Adenocarcinoma Endometrial Cancer
Interventions
DRUG
No Results Yet
NCT05794087 | RECRUITING | NA
120 Participants

The Role of Macrophage Activation in Lung Injury Following Ozone Exposure

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-02-07
Completion: 2027-06-01
Conditions
Air Pollution
Interventions
OTHER
No Results Yet
NCT05780788 | COMPLETED | NA
36 Participants

Characterizing Orthodontic Tooth Movement With Photographic Scans

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2020-12-31
Completion: 2024-03-20
Conditions
Canine Retraction
Interventions
DEVICE
NCT05774392 | WITHDRAWN
0 Participants

An Observational Study of Patients With Chronic Kidney Disease

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2025-04-30
Completion: 2025-04-07
Conditions
Kidney Disease, Chronic End Stage Kidney Disease
Interventions
OTHER
No Results Yet
NCT05774184 | ACTIVE_NOT_RECRUITING | PHASE2
86 Participants

A Study of CDX-0159 in Patients With Eosinophilic Esophagitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-06-01
Completion: 2025-06-04
Conditions
Eosinophilic Esophagitis
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT05766501 | ACTIVE_NOT_RECRUITING | PHASE3
641 Participants

A Study of Doravirine/Islatravir (DOR/ISL, MK-8591A) for the Treatment of Human Immunodeficiency Virus 1 (HIV-1) Infection in Participants Who Previously Received DOR/ISL (MK-8591A-054)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-03-17
Completion: 2025-10-16
Conditions
HIV Infection
Interventions
DRUG
No Results Yet
NCT05764733 | RECRUITING | PHASE4
900 Participants

Bone, Exercise, Alendronate, and Caloric Restriction

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-06-08
Completion: 2027-09-30
Conditions
Bone Loss
Interventions
DRUG BEHAVIORAL OTHER
No Results Yet
NCT05764720 | RECRUITING | NA
134 Participants

Stereotactic Adaptive Radiation Therapy of Borderline Resectable Pancreatic Cancer an Individualized Approach

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-05-14
Completion: 2026-02-15
Conditions
Pancreatic Cancer
Interventions
RADIATION
No Results Yet
NCT05763407 | RECRUITING | NA
25 Participants

Early Feasibility Study of the NORMâ„¢ System in Heart Failure Patients (FUTURE-HFII)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-06-19
Completion: 2026-06-30
Conditions
Heart Failure
Interventions
DEVICE
No Results Yet
NCT05754528 | ACTIVE_NOT_RECRUITING | PHASE4
240 Participants

Evaluating an Endocrine Therapy Dose-frequency Escalation Strategy and Its Effects on Tolerability and Compliance

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-07-28
Completion: 2025-12-31
Conditions
Breast Cancer
Interventions
DRUG
No Results Yet
NCT05735483 | ENROLLING_BY_INVITATION | PHASE3
310 Participants

A Study to Assess the Long-Term Safety and Efficacy of Lebrikizumab (LY3650150) in Participants 6 Months to <18 Years of Age With Moderate-to-Severe Atopic Dermatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-03-09
Completion: 2027-12-31
Conditions
Atopic Dermatitis Eczema
Interventions
DRUG
No Results Yet
NCT05734105 | ACTIVE_NOT_RECRUITING | PHASE3
54 Participants

A Study of Ripretinib vs Sunitinib in Patients With Advanced GIST With Specific KIT Exon Mutations Who Were Previously Treated With Imatinib

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-12-13
Completion: 2027-12-31
Conditions
GIST
Interventions
DRUG
No Results Yet
NCT05731271 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
111 Participants

A First-in-Human, Phase 1 Study of TST003 in Subjects With Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-02-08
Completion: 2026-06-30
Conditions
Locally Advanced Solid Tumor Metastatic Tumor Colorectal Adenocarcinoma
Interventions
DRUG
No Results Yet
NCT05725668 | RECRUITING | NA
336 Participants

A Study of Dual-task Exercise Training to Prevent Falls Among Older Adults With Mild Cognitive Impairment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-07-15
Completion: 2027-07-30
Conditions
Mild Cognitive Impairment Accidental Falls Aging
Interventions
BEHAVIORAL
No Results Yet
NCT05721573 | ACTIVE_NOT_RECRUITING | PHASE2/PHASE3
231 Participants

A Study to Evaluate the Efficacy and Safety of ABC008 for Inclusion Body Myositis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-02-28
Completion: 2025-11-06
Conditions
Inclusion Body Myositis
Interventions
DRUG
No Results Yet
NCT05721053 | ACTIVE_NOT_RECRUITING
150 Participants

Improving Outcomes for Older Adults Undergoing Radiation Therapy

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2022-11-09
Completion: 2025-10-31
Conditions
Cancer Radiation Therapy
No Results Yet
NCT05708716 | RECRUITING | NA
80 Participants

Diet and Cognitive Training in Hematologic Cancer Survivors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-11-22
Completion: 2026-12-31
Conditions
Cognitive Impairment Hematologic Malignancy
Interventions
BEHAVIORAL
No Results Yet
NCT05695339 | RECRUITING | PHASE1
24 Participants

Resiniferatoxin for the Management of Refractory Morton s Neuroma Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-03-13
Completion: 2026-12-01
Conditions
Morton's Neuroma
Interventions
DRUG
No Results Yet
NCT05693142 | RECRUITING | PHASE2/PHASE3
65 Participants

AFFINITY DUCHENNE: RGX-202 Gene Therapy in Participants With Duchenne Muscular Dystrophy (DMD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-01-04
Completion: 2026-02-28
Conditions
Duchenne Muscular Dystrophy
Interventions
GENETIC
No Results Yet
NCT05690984 | RECRUITING | PHASE2
31 Participants

Elimination of Minimal Residual Disease After Transplant

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-06-26
Completion: 2026-06-30
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT05670288 | RECRUITING
35 Participants

Impact of Gut Microbiome on Metabolic and Bowel Function During the First Year After Spinal Cord Injury

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2023-10-15
Completion: 2026-12-01
Conditions
Spinal Cord Injuries Gut Microbiome
No Results Yet
NCT05669027 | RECRUITING | NA
150 Participants

Mobile Neurofeedback for Low Back Pain

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-10-02
Completion: 2027-05-01
Conditions
Chronic Low Back Pain
Interventions
DEVICE
No Results Yet
NCT05668949 | WITHDRAWN | PHASE1/PHASE2
0 Participants

Phase I/II Open Label Study Evaluating the Safety and Efficacy of Combining STAT3 Inhibition (TTI-101) With Anti-PD-1 Therapy (Pembrolizumab) in Patients With Recurrent or Metastatic (RM) Head and Neck Squamous Cell Carcinoma (HNSCC)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2025-09-23
Completion: 2025-09-23
Conditions
Head and Neck Squamous Cell Carcinoma
Interventions
DRUG
No Results Yet
NCT05655520 | TERMINATED | PHASE3
153 Participants

A Study to Evaluate the Safety and Tolerability of SAGE-718 in Participants With Huntington's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-12-14
Completion: 2025-01-20
Conditions
Huntington's Disease
Interventions
DRUG
NCT05641155 | COMPLETED | NA
19 Participants

A Feasibility Study Evaluating the Performance of Focused Multipolar Stimulation and Sound Coding in Adults.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-06-02
Completion: 2025-02-06
Conditions
Hearing Impairment, Sensorineural
Interventions
DEVICE
No Results Yet
NCT05637762 | COMPLETED
13 Participants

Development of a Seizure Detection Algorithm Based on Heart Rate and Movement Analysis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2023-06-05
Completion: 2025-04-24
Conditions
Epilepsy
Interventions
OTHER
No Results Yet
NCT05635409 | ACTIVE_NOT_RECRUITING | PHASE1
8 Participants

A Trial to Determine the Safety and Tolerability of Transplanted Stem Cell Derived Dopamine Neurons to the Brains of Individuals With Parkinson's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-11-30
Completion: 2027-01-31
Conditions
Parkinson Disease
Interventions
BIOLOGICAL
No Results Yet
NCT05635019 | COMPLETED | NA
105 Participants

FoodRx for Obesity Treatment

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2022-12-01
Completion: 2024-07-01
Conditions
Obesity Food Insecurity
Interventions
BEHAVIORAL
NCT05632627 | COMPLETED | PHASE2
43 Participants

Cannabinoids and Traumatic Brain Injury: A Randomized, Placebo Controlled Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-04-11
Completion: 2025-07-07
Conditions
Brain Injuries, Traumatic
Interventions
DRUG
No Results Yet
NCT05617326 | RECRUITING | NA
400 Participants

Screening for Abdominal Aortic Aneurysms in the General Practice by Ultraportable Ultrasound

Study Type: INTERVENTIONAL
Last Updated: 2025-12-17
Start Date: 2023-10-02
Completion: 2027-09-01
Conditions
Abdominal Aortic Aneurysm
Interventions
OTHER
No Results Yet
NCT05612100 | RECRUITING
170 Participants

Endocrine Therapy-Induced Alopecia in Postmenopausal and Premenopausal Female Breast Cancer Patients

Study Type: OBSERVATIONAL
Last Updated: 2025-12-17
Start Date: 2022-07-06
Completion: 2028-06-30
Conditions
Breast Carcinoma
Interventions
OTHER
No Results Yet
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