A Study of Dual-task Exercise Training to Prevent Falls Among Older Adults With Mild Cognitive Impairment

NCT ID: NCT05725668

Last Updated: 2025-12-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

336 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-07-15

Study Completion Date

2028-01-31

Brief Summary

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To determine the efficacy of a dual-task tai ji quan training therapy in reducing the incidence of falls in older adults with mild cognitive impairment.

Detailed Description

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The primary aim of the study is to determine the comparative efficacy of two tai ji quan interventions (Dual-task tai ji quan, standard tai ji quan), relative to a stretching exercise control, in reducing the incidence of falls among community-dwelling older adults with mild cognitive impairment.

Conditions

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Mild Cognitive Impairment Accidental Falls Aging

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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Dual-task taj ji quan

This intervention includes training of (a) symmetrical postural tai ji quan forms/movements synchronized with breathing, (b) controlled displacement (weight-shifting) of the body's center of mass over the base of support, (c) dynamic eye-hand movements during whole-body motion, (d) multidirectional (anterior-posterior and medial-lateral) stepping, and (e) rotational ankle sway and self-induced reactive postural recovery actions. The training practices are integrated, gradually over time, with a mix of interactive, cognitively stimulating, dual-task exercises that challenge attention control, working memory, verbalization, response inhibition, processing speed, dual tasking, task switching/prioritization, and spatial orientation and postural awareness.

Group Type EXPERIMENTAL

dual-task tai ji quan

Intervention Type BEHAVIORAL

dual-task tai ji quan training

Standard tai ji quan

This intervention includes training of tai ji quan forms with synchronized breathing, supplemented by a set of mini-therapeutic exercises. The training involves repeated practice of (a) symmetrical, coordinated, trunk-driven tai ji quan form movements, (b) controlled displacement (weight-shifting) of the body's center of mass over varying sizes of the base of support, (c) dynamic eye-hand movements during whole-body motion, and (d) multidirectional (anterior-posterior and medial-lateral) stepping. As a balance training therapy, movement practices emphasize a dynamic interplay of stabilizing and self-induced destabilizing postural actions and balance exercises that target mobility, stability limits, and sensory integration.

Group Type EXPERIMENTAL

standard tai ji quan

Intervention Type BEHAVIORAL

standard tai ji quan training

Stretching exercise

This active control intervention includes light activities that consist of breathing, stretching, and relaxation exercises. Each exercise session encompasses a variety of light and static stretches for joints and muscles, performed in a seated or standing position. Exercise involves the upper body (arms, neck, upper back, shoulder, back, and chest), lower extremities (quadriceps, hamstrings/calfs, and hips), and gentle and slow trunk rotations. Also included are intermittent light walking, deep abdominal breathing exercises that emphasize inhaling and exhaling to maximum capacity, and progressive relaxation of major muscle groups.

Group Type EXPERIMENTAL

stretching

Intervention Type BEHAVIORAL

stretching exercise

Interventions

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dual-task tai ji quan

dual-task tai ji quan training

Intervention Type BEHAVIORAL

standard tai ji quan

standard tai ji quan training

Intervention Type BEHAVIORAL

stretching

stretching exercise

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* being 65 years and older
* having complaint of memory loss
* scoring ≤0.5 on Clinical Dementia Scale
* having had 1 or more falls in the preceding 12 months or scoring ≥12 seconds on the Timed Up and Go test

Exclusion Criteria

* scoring \<24 on the Mini-Mental State Examination
* being able to ambulate independently for household distances
* having medical clearance
* having participated in any regular and structured tai ji quan-based exercise programs (≥2 times weekly) in the preceding 6 months
* having a progressive neuromuscular disorder such as Parkinson's disease or multiple sclerosis
* being unwilling to be randomized
Minimum Eligible Age

65 Years

Maximum Eligible Age

95 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Oregon Research Institute

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Oregon Research Institute

Springfield, Oregon, United States

Site Status RECRUITING

Countries

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United States

Central Contacts

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Fuzhong Li, Ph.D.

Role: CONTACT

541-484-2123

Facility Contacts

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Fuzhong Li, Ph.D.

Role: primary

541-484-2123 ext. 2137

Other Identifiers

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AG074045-01A1

Identifier Type: -

Identifier Source: org_study_id