Trial Outcomes & Findings for Characterizing Orthodontic Tooth Movement With Photographic Scans (NCT NCT05780788)

NCT ID: NCT05780788

Last Updated: 2025-12-17

Results Overview

Deviation between the photographic and intraoral scan will be measured via root mean square (RMS) in millimeters (mm).

Recruitment status

COMPLETED

Study phase

NA

Target enrollment

36 participants

Primary outcome timeframe

Initial Deviation T0 (Baseline), Final Deviation T9 (34-37 days)

Results posted on

2025-12-17

Participant Flow

All subjects that were consented participated in the study

Participant milestones

Participant milestones
Measure
Canine retraction arm
Canine retraction Monitoring Tooth Movement: Monitoring Canine Retraction
Overall Study
STARTED
36
Overall Study
COMPLETED
22
Overall Study
NOT COMPLETED
14

Reasons for withdrawal

Withdrawal data not reported

Baseline Characteristics

The number of patients analyzed was based on usable data. Specifically, scans that were not of appropriate quality for measurements were excluded.

Baseline characteristics by cohort

Baseline characteristics by cohort
Measure
Canine Retraction Arm
n=22 Participants
Canine retraction Monitoring Tooth Movement: Monitoring Canine Retraction
Age, Categorical
<=18 years
17 Participants
n=6 Participants • The number of patients analyzed was based on usable data. Specifically, scans that were not of appropriate quality for measurements were excluded.
Age, Categorical
Between 18 and 65 years
5 Participants
n=6 Participants • The number of patients analyzed was based on usable data. Specifically, scans that were not of appropriate quality for measurements were excluded.
Age, Categorical
>=65 years
0 Participants
n=6 Participants • The number of patients analyzed was based on usable data. Specifically, scans that were not of appropriate quality for measurements were excluded.
Age, Continuous
17.41 years
STANDARD_DEVIATION 5.51 • n=6 Participants • The number of patients analyzed was based on usable data. Specifically, scans that were not of appropriate quality for measurements were excluded.
Sex: Female, Male
Female
16 Participants
n=6 Participants • The number of patients analyzed was based on usable data. Specifically, scans that were not of appropriate quality for measurements were excluded.
Sex: Female, Male
Male
6 Participants
n=6 Participants • The number of patients analyzed was based on usable data. Specifically, scans that were not of appropriate quality for measurements were excluded.
Race (NIH/OMB)
American Indian or Alaska Native
0 Participants
n=6 Participants • Measure Analysis Population Description: The number of patients analyzed was based on usable data. Specifically, scans that were not of appropriate quality for measurements were excluded.
Race (NIH/OMB)
Asian
5 Participants
n=6 Participants • Measure Analysis Population Description: The number of patients analyzed was based on usable data. Specifically, scans that were not of appropriate quality for measurements were excluded.
Race (NIH/OMB)
Native Hawaiian or Other Pacific Islander
0 Participants
n=6 Participants • Measure Analysis Population Description: The number of patients analyzed was based on usable data. Specifically, scans that were not of appropriate quality for measurements were excluded.
Race (NIH/OMB)
Black or African American
6 Participants
n=6 Participants • Measure Analysis Population Description: The number of patients analyzed was based on usable data. Specifically, scans that were not of appropriate quality for measurements were excluded.
Race (NIH/OMB)
White
6 Participants
n=6 Participants • Measure Analysis Population Description: The number of patients analyzed was based on usable data. Specifically, scans that were not of appropriate quality for measurements were excluded.
Race (NIH/OMB)
More than one race
0 Participants
n=6 Participants • Measure Analysis Population Description: The number of patients analyzed was based on usable data. Specifically, scans that were not of appropriate quality for measurements were excluded.
Race (NIH/OMB)
Unknown or Not Reported
5 Participants
n=6 Participants • Measure Analysis Population Description: The number of patients analyzed was based on usable data. Specifically, scans that were not of appropriate quality for measurements were excluded.
Region of Enrollment
United States
22 Participants
n=6 Participants • The number of patients analyzed was based on usable data. Specifically, scans that were not of appropriate quality for measurements were excluded.

PRIMARY outcome

Timeframe: Initial Deviation T0 (Baseline), Final Deviation T9 (34-37 days)

Population: A total of 36 participants were enrolled in the study. Due to scan quality issues, only 22 participants had usable data for analysis. Specifically, 13 participants were analyzed for the Initial Deviation outcome, and 15 participants for the Final Deviation outcome.

Deviation between the photographic and intraoral scan will be measured via root mean square (RMS) in millimeters (mm).

Outcome measures

Outcome measures
Measure
Canine retraction arm
n=22 Participants
Canine retraction Monitoring Tooth Movement: Monitoring Canine Retraction
Accuracy Between Patient-taken DM Scan and Provider-taken iTero Scan
Initial Deviation T0 (Baseline)
0.0001 Millimeters (mm)
Interval 0.0001 to 0.0005
Accuracy Between Patient-taken DM Scan and Provider-taken iTero Scan
Final Deviation T9 (34-37 days)
0.0500 Millimeters (mm)
Interval 0.04 to 0.06

SECONDARY outcome

Timeframe: T1 (3-5 days), T2 (6-9 days), T3 (10-13 days), T4 (14-17 days), T5 (18-21 days), T6 (22-25 days), T7 (26-29 days), T8 (30-33 days), T9 (34-37days).

Population: A total of 36 participants were enrolled, but only 21 had usable data due to scan quality issues. Each tooth (canine and molar on both sides) was analyzed individually, and analysis could vary by side. Sample sizes varied by tooth and time point depending on image availability.

Magnitude of canine tooth movement for every 4-5 days during a one month period. Measurements will be done in mm in three planes of space. Measurement reported in mm at each timepoint is the cumulative movement up to that timpoint during the one month of monitoring of tooth movement.

Outcome measures

Outcome measures
Measure
Canine retraction arm
n=21 Participants
Canine retraction Monitoring Tooth Movement: Monitoring Canine Retraction
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in y- axis (vertical) T1 (3-5 days)
-0.06 Millimeters
Interval -0.09 to -0.03
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in z- axis (transverse) T1 (3-5 days)
-0.03 Millimeters
Interval -0.14 to 0.01
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in x- axis (anteroposterior) T1 (3-5 days)
-0.39 Millimeters
Interval -0.54 to -0.26
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in y- axis (vertical) T1 (3-5 days)
-0.10 Millimeters
Interval -0.15 to -0.03
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in z- axis (transverse) T1 (3-5 days)
-0.13 Millimeters
Interval -0.23 to 0.01
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in x- axis (anteroposterior)T2 (6-9 days)
-0.515 Millimeters
Interval -0.67 to -0.395
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in y- axis (vertical) T2 (6-9 days)
-0.07 Millimeters
Interval -0.12 to -0.05
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in z- axis (transverse) T2 (6-9 days)
-0.11 Millimeters
Interval -0.15 to -0.04
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in x- axis (anteroposterior) T2 (6-9 days)
-0.66 Millimeters
Interval -0.79 to -0.45
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in y- axis (vertical) T2 (6-9 days)
-0.11 Millimeters
Interval -0.17 to 0.01
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in z- axis (transverse) T2 (6-9 days)
-0.21 Millimeters
Interval -0.35 to -0.06
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in x- axis (anteroposterior)T3 (10-13days)
-0.52 Millimeters
Interval -0.8 to -0.28
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in z- axis (transverse) T3 (10-13 days)
-0.21 Millimeters
Interval -0.39 to -0.05
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in x- axis (anteroposterior)T4 (14-17 days)
-0.74 Millimeters
Interval -0.88 to -0.52
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in x- axis (anteroposterior)T5 (18-21 days)
-0.82 Millimeters
Interval -1.04 to -0.58
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in y- axis (vertical) T5 (18-21 days)
-0.18 Millimeters
Interval -0.26 to -0.11
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in z- axis (transverse) T5 (18-21 days)
-0.16 Millimeters
Interval -0.4 to -0.03
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in x- axis (anteroposterior) T5 (18-21 days)
-0.94 Millimeters
Interval -1.18 to -0.74
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in y- axis (vertical) T5 (18-21 days)
-0.17 Millimeters
Interval -0.33 to -0.05
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in z- axis (transverse) T5 (18 -21days)
-0.27 Millimeters
Interval -0.52 to -0.06
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in x- axis (anteroposterior)T6 (22-25 days)
-0.98 Millimeters
Interval -1.17 to -0.72
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in y- axis (vertical) T6 (22-25 days)
-0.22 Millimeters
Interval -0.28 to -0.11
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in z- axis (transverse) T6 (22 -25days)
-0.21 Millimeters
Interval -0.55 to 0.0
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in x- axis (anteroposterior) T6 (22-25 days)
-1.14 Millimeters
Interval -1.28 to -0.86
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in y- axis (vertical) T6 (22-25 days)
-0.22 Millimeters
Interval -0.37 to -0.1
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in z- axis (transverse) T6 (22-25 days)
-0.30 Millimeters
Interval -0.6 to -0.06
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in x- axis (anteroposterior) T7 (26-29 days)
-0.99 Millimeters
Interval -1.29 to -0.68
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in y- axis (vertical) T7 (26-29 days)
-0.23 Millimeters
Interval -0.36 to -0.16
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in z- axis (transverse) T7 (26-29 days)
-0.24 Millimeters
Interval -0.46 to -0.03
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in x- axis (anteroposterior) T7 (26-29 days)
-1.16 Millimeters
Interval -1.36 to -0.93
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in x- axis (anteroposterior) T8 (30-33 days)
-1.08 Millimeters
Interval -1.43 to -0.66
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in y- axis (vertical) T8 (30-33 days)
-0.32 Millimeters
Interval -0.4 to -0.18
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in z- axis (transverse) T8 (30-33 days)
-0.30 Millimeters
Interval -0.58 to -0.06
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in x- axis (anteroposterior) T9 (34 -37days)
-1.19 Millimeters
Interval -1.44 to -0.82
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in y- axis (vertical) T9 (34 -37days)
-0.35 Millimeters
Interval -0.56 to -0.18
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in z- axis (transverse) T9 (34 -37days)
-0.24 Millimeters
Interval -0.75 to -0.08
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in x- axis (anteroposterior) T9 (34-37 days)
-1.14 Millimeters
Interval -1.44 to -0.75
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in x- axis (anteroposterior)T1 (3-5 days)
-0.36 Millimeters
Interval -0.46 to -0.15
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in y- axis (vertical) T3 (10-13 days)
-0.13 Millimeters
Interval -0.15 to -0.07
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in z- axis (transverse) T3(10-13 days)
-0.07 Millimeters
Interval -0.11 to -0.02
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in x- axis (anteroposterior) T3 (10-13 days)
-0.82 Millimeters
Interval -0.97 to -0.57
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in y- axis (vertical) T3 (10-13 days)
-0.14 Millimeters
Interval -0.21 to -0.01
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in y- axis (vertical) T4 (14-17 days)
-0.14 Millimeters
Interval -0.21 to -0.07
Tracking Maxillary Canine Tooth Movement (Displacement)
Right canine displacement movement in z- axis (transverse) T4 (14-17 days)
-0.12 Millimeters
Interval -0.34 to -0.03
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in x- axis (anteroposterior) T4 (14-17 days)
-0.76 Millimeters
Interval -1.04 to -0.63
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in y- axis (vertical) T4 (14-17 days)
-0.18 Millimeters
Interval -0.27 to -0.07
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in z- axis (transverse) T4 (14-17 days)
-0.28 Millimeters
Interval -39.0 to -0.09
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in y- axis (vertical) T7 (26-29 days)
-0.22 Millimeters
Interval -0.35 to -0.19
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in z- axis (transverse) T7 (26-29 days)
-0.30 Millimeters
Interval -0.57 to -0.06
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in x- axis (anteroposterior) T8 (30-33 days)
-1.29 Millimeters
Interval -1.67 to -1.01
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in y- axis (vertical) T8 (30-33 days)
-0.32 Millimeters
Interval -0.53 to -0.24
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in z- axis (transverse) T8 (30-33 days)
-0.42 Millimeters
Interval -0.75 to -0.3
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in y- axis (vertical) T9 (34-37 days)
-0.34 Millimeters
Interval -0.47 to -0.03
Tracking Maxillary Canine Tooth Movement (Displacement)
Left canine displacement movement in z- axis (transverse) T9 (34-37 days)
-0.39 Millimeters
Interval -0.87 to -0.32

SECONDARY outcome

Timeframe: T1 (3-5 days), T2 (6-9 days), T3 (10-13 days), T4 (14-17 days), T5 (18-21 days), T6 (22-25 days), T7 (26-29 days), T8 (30-33 days), T9 (34-37days).

Population: Not all patients have data for every timepoint or side.

Magnitude of maxillary first molar tooth movement for every 4-5 days during a one month period. Measurements will be done in mm in three planes of space.

Outcome measures

Outcome measures
Measure
Canine retraction arm
n=21 Participants
Canine retraction Monitoring Tooth Movement: Monitoring Canine Retraction
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement movement in z- axis (transverse) T8 (30-33 days)
-0.13 Millimeters
Interval -0.38 to 0.05
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement movement in x- axis (anteroposterior)T9 (34-37 days)
0.34 Millimeters
Interval 0.2 to 0.41
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement movement in y- axis (vertical) T3 (10-13 days)
-0.11 Millimeters
Interval -0.13 to -0.01
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement movement in z- axis (transverse) T3 (10-13 days)
-0.02 Millimeters
Interval -0.17 to 0.03
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement movement in x- axis (anteroposterior)T4 (14-17 days)
0.14 Millimeters
Interval 0.02 to 0.25
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement movement in y- axis (vertical) T4 (14-17 days)
-0.12 Millimeters
Interval -0.16 to -0.01
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement movement in z- axis (transverse) T4 (14-17 days)
-0.14 Millimeters
Interval -0.2 to 0.06
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement movement in x- axis (anteroposterior)T5 (18-21 days)
0.15 Millimeters
Interval 0.0 to 0.25
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement movement in y- axis (vertical) T5 (18 -21days)
-0.10 Millimeters
Interval -0.18 to 0.0
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement movement in x- axis (anteroposterior)T7 (26-29 days)
0.25 Millimeters
Interval 0.11 to 0.41
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement movement in y- axis (vertical) T7 (26-29 days)
-0.14 Millimeters
Interval -0.21 to 0.04
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement movement in z- axis (transverse) T7 (26-29 days)
-0.05 Millimeters
Interval -0.27 to 0.01
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement movement in x- axis (anteroposterior)T7 (26-29 days)
0.08 Millimeters
Interval -0.05 to 0.18
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement movement in y- axis (vertical) T7 (26-29 days)
-0.16 Millimeters
Interval -0.25 to -0.03
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement movement in z- axis (transverse) T7 (26-29 days)
-0.11 Millimeters
Interval -0.28 to 0.08
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement movement in x- axis (anteroposterior)T8 (30-33 days)
0.23 Millimeters
Interval 0.08 to 0.34
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement movement in z- axis (transverse) T8 (30-33 days)
-0.19 Millimeters
Interval -0.33 to -0.1
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement movement in x- axis (anteroposterior)T8 (30-33 days)
0.00 Millimeters
Interval -0.14 to 0.12
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement movement in y- axis (vertical) T8 (30-33 days)
-0.19 Millimeters
Interval -0.32 to -0.16
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement movement in z- axis (transverse) T5 (18-21 days)
-0.09 Millimeters
Interval -0.23 to 0.07
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement movement in x- axis (anteroposterior)T6 (22-25 days)
0.13 Millimeters
Interval 0.07 to 0.24
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement movement in y- axis (vertical) T6 (22-25 days)
-0.09 Millimeters
Interval -0.18 to 0.03
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement movement in z- axis (transverse) T6 (22 -25 days)
-0.13 Millimeters
Interval -0.32 to -0.06
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement movement in x- axis (anteroposterior)T6 (22-25 days)
-0.02 Millimeters
Interval -0.09 to 0.09
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement movement in y- axis (vertical) T6 (22-25 days)
-0.15 Millimeters
Interval -0.2 to -0.05
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement movement in z- axis (transverse) T6 (22-25 days)
-0.04 Millimeters
Interval -0.32 to 0.13
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement movement in y- axis (vertical) T8 (30-33 days)
-0.10 Millimeters
Interval -0.2 to -0.01
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement movement in y- axis (vertical) T9 (34-37 days)
-0.07 Millimeters
Interval -0.19 to -0.06
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement movement in z- axis (transverse) T9 (34-37 days)
-0.17 Millimeters
Interval -0.36 to -0.03
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement movement in x- axis (anteroposterior)T9 (34-37 days)
-0.01 Millimeters
Interval -0.05 to 0.1
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement movement in y- axis (vertical) T9 (34-37 days)
-0.15 Millimeters
Interval -0.23 to -0.1
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement movement in z- axis (transverse) T9 (34 -37 days)
-0.02 Millimeters
Interval -0.2 to 0.17
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement in z-axis (transverse) T1 3-5 days)
0.00 Millimeters
Interval -0.02 to 0.01
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement movement in x- axis (anteroposterior)T2 (6-9 days)
0.03 Millimeters
Interval 0.01 to 0.15
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement movement in y- axis (vertical) T2 (6-9 days)
-0.09 Millimeters
Interval -0.09 to 0.0
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement movement in z- axis (transverse) T2 (6-9 days)
-0.05 Millimeters
Interval -0.17 to 0.0
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement movement in x- axis (anteroposterior)T2 (6-9 days)
0.02 Millimeters
Interval -0.01 to 0.11
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement movement in y- axis (vertical) T2 (6-9 days)
-0.04 Millimeters
Interval -0.12 to 0.01
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement movement in x- axis (anteroposterior)T3 (10-13 days)
0.03 Millimeters
Interval -0.01 to 0.09
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement in x-axis (anteroposterior) T1 (3-5 days)
0.03 Millimeters
Interval 0.01 to 0.1
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement in y-axis (vertical) T1 (3-5 days)
-0.01 Millimeters
Interval -0.05 to 0.02
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement in z-axis (transverse) T1 (3-5 days)
-0.04 Millimeters
Interval -0.1 to 0.0
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement in x-axis (anteroposterior) T1 (3-5 days)
0.01 Millimeters
Interval 0.0 to 0.07
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement in y-axis (vertical) T1 (3-5 days)
-0.02 Millimeters
Interval -0.04 to 0.01
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement movement in z- axis (transverse) T2 (6-9 days)
-0.05 Millimeters
Interval -0.17 to 0.03
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement movement in x- axis (anteroposterior)T3 (10-13 days)
0.08 Millimeters
Interval 0.01 to 0.17
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement movement in y- axis (vertical) T3 (10-13 days)
-0.08 Millimeters
Interval -0.1 to -0.05
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement movement in z- axis (transverse) T3 (10-13 days)
-0.05 Millimeters
Interval -0.12 to 0.0
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement movement in y- axis (vertical) T4 (14-17 days)
-0.06 Millimeters
Interval -0.14 to -0.03
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement movement in z- axis (transverse) T4 (14-17 days)
-0.07 Millimeters
Interval -0.25 to -0.03
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement movement in x- axis (anteroposterior)T4 (14-17 days)
0.02 Millimeters
Interval -0.06 to 0.12
Tracking Maxillary First Molar Movement (Displacement)
Right molar displacement movement in z- axis (transverse) T5 (18-21 days)
-0.09 Millimeters
Interval -0.26 to -0.02
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement movement in x- axis (anteroposterior)T5 (18-21 days)
0.04 Millimeters
Interval -0.04 to 0.18
Tracking Maxillary First Molar Movement (Displacement)
Left molar displacement movement in y- axis (vertical) T5 (18-21 days)
-0.12 Millimeters
Interval -0.16 to -0.06

SECONDARY outcome

Timeframe: T1 (3-5 days), T2 (6-9 days), T3 (10-13 days), T4 (14-17 days), T5 (18-21 days), T6 (22-25 days), T7 (26-29 days), T8 (30-33 days), T9 (34-37days).

Population: A total of 36 participants were enrolled, but only 21 had usable data due to scan quality issues. Each tooth (canine and molar on both sides) was analyzed individually, and analysis could vary by side. Sample sizes varied by tooth and time point depending on image availability.

Magnitude of canine tooth movement for every 4-5 days during a one month period. Measurements will be done in degrees in three planes of space.

Outcome measures

Outcome measures
Measure
Canine retraction arm
n=21 Participants
Canine retraction Monitoring Tooth Movement: Monitoring Canine Retraction
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (z -axis) T1 3-5 days)
0.06 degrees
Interval -0.17 to 0.21
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (x -axis) T2 (6-9 days)
0.00 degrees
Interval -0.28 to 0.57
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (y -axis) T2 (6-9 days)
-1.64 degrees
Interval -2.9 to -0.88
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (z-axis) T2 (6-9 days)
-0.07 degrees
Interval -0.68 to 0.32
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (x -axis) T2 (6-9 days)
-0.20 degrees
Interval -0.36 to 0.05
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (z-axis) T4 (14-17 days)
-0.47 degrees
Interval -1.69 to -0.1
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (x -axis) T4 (14-17 days)
-0.38 degrees
Interval -1.04 to -0.24
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (y -axis) T4 (14-17 days)
-2.19 degrees
Interval -4.38 to -0.64
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (z -axis) T4 (14-17 days)
-0.91 degrees
Interval -1.4 to -0.56
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (x -axis) T5 (18-21 days)
-0.52 degrees
Interval -1.25 to -0.02
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (y-axis) T5 (18-21 days)
-3.06 degrees
Interval -4.56 to -1.95
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (z -axis) T5 (18-21 days)
-0.82 degrees
Interval -1.48 to -0.28
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (x -axis) T5 (18-21 days)
-0.69 degrees
Interval -1.44 to -0.16
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (y -axis) T5 (18-21 days)
-3.75 degrees
Interval -3.97 to -0.78
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (z -axis) T5 (18-21 days)
-0.97 degrees
Interval -1.99 to -0.39
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (z -axis) T7 (26-29 days)
-1.18 degrees
Interval -1.65 to -0.33
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (x -axis) T7 (26-29 days)
-0.76 degrees
Interval -1.24 to -0.13
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (y-axis) T7 (26-29 days)
-2.93 degrees
Interval -6.47 to -1.54
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (z -axis) T7 (26-29 days)
-1.29 degrees
Interval -1.87 to -0.71
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (x -axis) T8 (30-33 days)
-1.04 degrees
Interval -2.01 to -0.18
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (y -axis) T8 (30-33 days)
-3.67 degrees
Interval -4.53 to -2.1
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (z -axis) T8 (30-33 days)
-1.16 degrees
Interval -1.41 to 0.04
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (x -axis) T8 (30-33 days)
-0.77 degrees
Interval -1.43 to -0.13
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (y -axis) T9 (34-37 days)
-3.06 degrees
Interval -7.05 to -3.0
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (z -axis) T9 (34-37 days)
-0.71 degrees
Interval -1.61 to -0.12
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (x -axis) T1 (3-5 days)
0.19 degrees
Interval -0.13 to 0.52
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (y -axis) T1 (3-5 days)
-0.34 degrees
Interval -0.83 to 0.13
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (z-axis) T1 (3-5 days)
0.02 degrees
Interval -0.35 to 0.27
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (x -axis) T1 (3-5 days)
-0.01 degrees
Interval -0.25 to 0.15
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (y -axis) T1 (3-5 days)
-0.66 degrees
Interval -3.45 to -0.05
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (y -axis) T2 (6-9 days)
-2.28 degrees
Interval -3.5 to -0.55
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (z -axis) T2 (6-9 days)
-0.36 degrees
Interval -0.78 to 0.0
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (x -axis) T3 (10-13 days)
0.04 degrees
Interval -0.1 to 0.31
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (y -axis) T3 (10-13 days)
-2.14 degrees
Interval -4.39 to -0.69
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (z-axis) T3 (10-13 days)
-0.28 degrees
Interval -1.14 to 0.61
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (x -axis) T3 (10-13 days)
-0.32 degrees
Interval -1.01 to 0.09
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (y -axis) T3 (10-13 days)
-1.23 degrees
Interval -3.34 to 0.06
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (z -axis) T3 (10-13 days)
-0.82 degrees
Interval -1.12 to -0.23
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (x -axis) T4 (14-17 days)
-0.24 degrees
Interval -0.76 to 0.05
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (y -axis) T4 (14-17 days)
-2.23 degrees
Interval -4.29 to -1.15
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (x -axis) T6 (22-25 days)
-0.72 degrees
Interval -1.02 to -0.15
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (y -axis) T6 (22-25 days)
-3.61 degrees
Interval -6.09 to -2.14
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (z -axis) T6 (22-25 days)
-1.51 degrees
Interval -1.82 to -0.74
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (x -axis) T6 (22-25 days)
-0.80 degrees
Interval -1.19 to -0.15
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (y -axis) T6 (22-25 days)
-3.76 degrees
Interval -6.39 to -1.34
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (z -axis) T6 (22-25 days)
-1.04 degrees
Interval -2.0 to -0.53
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (x -axis) T7 (26-29 days)
-0.41 degrees
Interval -1.59 to -0.08
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (y -axis) T7 (26-29 days)
-3.50 degrees
Interval -4.63 to -1.94
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (y -axis) T8 (30-33 days)
-4.17 degrees
Interval -7.86 to -2.47
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (z -axis) T8 (30-33 days)
-2.23 degrees
Interval -2.68 to -0.42
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (x -axis) T9 (34-37 days)
-0.43 degrees
Interval -1.74 to 0.35
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (y -axis) T9 (34-7 days)
-3.96 degrees
Interval -5.03 to -2.96
Tracking Maxillary Canine Tooth Movement (Rotation)
Right canine rotational movement (z -axis) T9 (34-37 days)
-1.67 degrees
Interval -2.02 to -0.6
Tracking Maxillary Canine Tooth Movement (Rotation)
Left canine rotational movement (x -axis) T9 (34-37 days)
-0.72 degrees
Interval -1.46 to -0.26

SECONDARY outcome

Timeframe: T1 (3-5 days), T2 (6-9 days), T3 (10-13 days), T4 (14-17 days), T5 (18-21 days), T6 (22-25 days), T7 (26-29 days), T8 (30-33 days), T9 (34-37days).

Population: A total of 36 participants were enrolled, but only 21 had usable data due to scan quality issues. Each tooth (canine and molar on both sides) was analyzed individually, and analysis could vary by side. Sample sizes varied by tooth and time point depending on image availability.

Magnitude of maxillary first molar tooth movement for every 4-5 days during a one month period. Measurements will be done in degrees in three planes of space.

Outcome measures

Outcome measures
Measure
Canine retraction arm
n=21 Participants
Canine retraction Monitoring Tooth Movement: Monitoring Canine Retraction
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (x-axis) T1 (3-5 days)
-0.06 Degrees
Interval -0.36 to 0.05
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (y-axis) T1 (3-5 days)
0.00 Degrees
Interval -0.28 to 0.3
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (z-axis) T1 (3-5 days)
-0.00 Degrees
Interval -0.24 to 0.28
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (x-axis) T1 3-5 days)
0.02 Degrees
Interval -0.18 to 0.23
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (y-axis)T1 (3-5 days)
0.20 Degrees
Interval 0.0 to 0.39
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (z-axis) T1 (3-5 days)
0.00 Degrees
Interval -0.18 to 0.11
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (x -axis) T2 (6-9 days)
0.03 Degrees
Interval -0.03 to 0.23
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (y -axis) T2 (6-9 days)
0.55 Degrees
Interval 0.15 to 0.97
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (z -axis) T2 (6-9 days)
0.11 Degrees
Interval -0.31 to 0.42
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (y -axis) T4 (14-17 days)
0.52 Degrees
Interval -0.27 to 1.7
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (z -axis) T4 (14-17 days)
0.21 Degrees
Interval -0.26 to 0.54
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (x -axis) T4 (14-17 days)
-0.24 Degrees
Interval -0.4 to 0.38
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (y -axis) T4 (14-17 days)
0.62 Degrees
Interval 0.3 to 1.02
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (z -axis) T4 (14-17 days)
0.11 Degrees
Interval -0.42 to 0.63
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (x -axis) T5 (18-21 days)
-0.13 Degrees
Interval -0.58 to 0.36
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (y -axis) T5 (18-21 days)
1.46 Degrees
Interval 0.07 to 2.13
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (z -axis) T5 (18-21 days)
0.53 Degrees
Interval -0.2 to 0.91
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (x -axis) T5 (18-21 days)
-0.11 Degrees
Interval -0.42 to 0.75
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (y -axis) T5 (18-21 days)
0.94 Degrees
Interval 0.78 to 2.35
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (z -axis) T5 (18-21 days)
0.26 Degrees
Interval -0.65 to 0.86
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (x -axis) T6 (22-25 days)
-0.34 Degrees
Interval -0.82 to 0.65
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (y -axis) T6 (22-25 days)
0.59 Degrees
Interval -0.75 to 2.95
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (z -axis) T6 (22-25 days)
0.07 Degrees
Interval -0.35 to 0.83
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (x -axis) T6 (22-25 days)
0.49 Degrees
Interval -0.36 to 0.96
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (y -axis) T6 (22-25 days)
1.46 Degrees
Interval 0.81 to 2.11
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (z -axis) T7 (26-29 days)
0.39 Degrees
Interval 0.0 to 1.28
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (x -axis) T7 (26-29 days)
0.20 Degrees
Interval -0.38 to 0.99
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (y -axis) T7 (26-29 days)
1.53 Degrees
Interval 1.13 to 2.56
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (x -axis) T8 (30-33 days)
-0.59 Degrees
Interval -0.97 to -0.14
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (y -axis) T8 (30-33 days)
1.93 Degrees
Interval 0.31 to 3.24
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (z -axis) T8 (30-33 days)
0.98 Degrees
Interval 0.16 to 1.45
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (x -axis) T8 (30-33 days)
-0.01 Degrees
Interval -0.93 to 0.33
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (y -axis) T8 (30-33 days)
1.78 Degrees
Interval 0.36 to 3.33
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (z -axis) T8 (30-33 days)
0.45 Degrees
Interval -0.05 to 1.22
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (x -axis) T9 (34-37 days)
3.13 Degrees
Interval -0.04 to 3.29
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (y-axis) T9 (34-37 days)
0.57 Degrees
Interval 0.13 to 1.08
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (z -axis) T9 (34-37 days)
0.77 Degrees
Interval 0.07 to 1.34
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (x -axis) T9 (34-37 days)
0.60 Degrees
Interval -0.64 to 0.68
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (y -axis) T9 (34-37 days)
2.67 Degrees
Interval 1.29 to 4.35
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (z -axis) T9 (34-37 days)
0.97 Degrees
Interval 0.42 to 1.07
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (x -axis) T2 (6-9 days)
-0.14 Degrees
Interval -0.4 to 0.01
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (y -axis) T2 (6-9 days)
0.05 Degrees
Interval -0.22 to 0.54
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (z -axis) T2 (6-9 days)
0.00 Degrees
Interval -0.44 to 0.82
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (x -axis) T3 (10-13 days)
-0.46 Degrees
Interval -0.85 to 0.08
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (y -axis) T3 (10-13 days)
0.24 Degrees
Interval -0.28 to 0.69
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (z -axis) T3 (10-13 days)
-0.07 Degrees
Interval -0.55 to 0.37
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (x -axis) T3 (10-13 days)
0.20 Degrees
Interval -0.16 to 0.39
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (y -axis) T3 (10-13 days)
0.44 Degrees
Interval 0.2 to 0.87
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (z -axis) T3 (10-13 days)
0.24 Degrees
Interval -0.22 to 1.17
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (x -axis) T4 (14-17 days)
-0.48 Degrees
Interval -0.76 to -0.31
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (z -axis) T6 (22-25 days)
0.76 Degrees
Interval -0.24 to 1.23
Tracking Maxillary First Molar Displacement (Rotation)
Righ molar rotational movement (x -axis) T7 (26-29 days)
-0.35 Degrees
Interval -0.89 to 0.23
Tracking Maxillary First Molar Displacement (Rotation)
Right molar rotational movement (y -axis) T7 (26-29 days)
1.31 Degrees
Interval -0.68 to 3.06
Tracking Maxillary First Molar Displacement (Rotation)
Left molar rotational movement (z -axis) T7 (26-29 days)
0.41 Degrees
Interval -1.01 to 1.25

Adverse Events

Canine retraction arm

Serious events: 0 serious events
Other events: 0 other events
Deaths: 0 deaths

Serious adverse events

Adverse event data not reported

Other adverse events

Adverse event data not reported

Additional Information

Dr. Flavio Uribe (Study principal investigator)

UConn Health - Department of Orthodontics

Phone: 8606792550

Results disclosure agreements

  • Principal investigator is a sponsor employee
  • Publication restrictions are in place