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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06720896 | RECRUITING | PHASE2
100 Participants

A Phase 2, Controlled, Double Blind, Randomized and Multicenter Study to Compare Efficacy and Safety of a Novel Topical Therapy (APT-001, Spinosad 1.8%) in Patients With Blepharitis.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-11-01
Completion: 2026-04-30
Conditions
Blepharitis
Interventions
DRUG
No Results Yet
NCT06717919 | RECRUITING | PHASE4
220 Participants

HOPE Against Cancer Recurrence in HCC

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-08-01
Completion: 2028-01-31
Conditions
Liver Transplantation HCC Oncological Outcomes
Interventions
PROCEDURE
No Results Yet
NCT06712797 | RECRUITING | NA
24 Participants

Physical Activity and Nutrition to Halt Elevated Risk in the Pancreas Interception Center

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-02-19
Completion: 2027-11-30
Conditions
Pancreatic Ductal Adenocarcinoma Intraductal Papillary Mucinous Neoplasm
Interventions
BEHAVIORAL
No Results Yet
NCT06710210 | NOT_YET_RECRUITING | NA
150 Participants

Hybrid Percutaneous Coronary Intervention Combining a Bioresorbable Scaffold With Drug-coated Balloons Versus a Conventional Drug-eluting Stent-based Strategy in Patients With Long and Diffuse Coronary Artery Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2026-01-01
Completion: 2027-01-01
Conditions
Coronary Artery Disease Diffuse Coronary Artery Disease Percutaneous Coronary Intervention (PCI)
Interventions
DEVICE
No Results Yet
NCT06698900 | COMPLETED
1000 Participants

This Project Aims to Understand the Needs of Rheumatologists and Other Specialties in the Care of Patients With SLE

Study Type: OBSERVATIONAL
Last Updated: 2025-12-16
Start Date: 2024-11-29
Completion: 2024-12-20
Conditions
Systemic Lupus Erythematosus
No Results Yet
NCT06698055 | COMPLETED | NA
91 Participants

Muscle Adaptations in Children and Adults Following Twelve Weeks of Flywheel or Weight Stack Resistance Exercise

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2022-08-28
Completion: 2025-02-02
Conditions
Resistance Exercise Muscle Hypertrophy Skeletal Muscle EMG Magnetic Resonance Imaging Growth Plate Early Closing Children, Adult
Interventions
OTHER
No Results Yet
NCT06685861 | ACTIVE_NOT_RECRUITING | NA
146 Participants

Effectiveness of Digital Cognitive Behavioral Therapy for the Treatment of Depression

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2024-11-11
Completion: 2025-12-30
Conditions
Depression
Interventions
DEVICE
No Results Yet
NCT06660004 | COMPLETED | NA
36 Participants

Creatine HCl and Creatine Ethyl Ester Supplementation in Perimenopausal and Menopausal Women

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2024-11-15
Completion: 2025-05-15
Conditions
Menopausal Perimenopause
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT06646471 | RECRUITING | PHASE4
500 Participants

PROspective Master-protocol for Evaluation of Systemic THErapeutics in Elderly With Thoracic Malignancies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2024-09-26
Completion: 2026-08-31
Conditions
Non Small Cell Lung Cancer Lung Cancer
Interventions
GENETIC OTHER PROCEDURE
No Results Yet
NCT06646237 | NOT_YET_RECRUITING
350 Participants

Diagnostic Utility of Mycobacterium Tuberculosis Cell-free DNA in Hong Kong

Study Type: OBSERVATIONAL
Last Updated: 2025-12-16
Start Date: 2026-01-01
Completion: 2027-12-31
Conditions
Tuberculosis, Pleural Pleural Biopsy
No Results Yet
NCT06640647 | COMPLETED | PHASE1
65 Participants

Phase Ia Clinical Study of HDM1005 Injection

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2024-03-19
Completion: 2024-08-06
Conditions
Obesity and Overweight
Interventions
DRUG
No Results Yet
NCT06637358 | COMPLETED | NA
69 Participants

A Text-based Reduction Intervention for Smokeless Tobacco Cessation- Pilot Study

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2024-11-05
Completion: 2025-11-04
Conditions
Smokeless Tobacco Cessation
Interventions
BEHAVIORAL
No Results Yet
NCT06637020 | COMPLETED | PHASE1
40 Participants

Phase Ib Clinical Study of HDM1005 Injection

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2024-06-20
Completion: 2024-12-27
Conditions
Overweight and Obesity
Interventions
DRUG
No Results Yet
NCT06632184 | ACTIVE_NOT_RECRUITING | PHASE4
40 Participants

Peritoneal Lavage Using Saline or Saline With Ondansetron for Pain Control After Laparoscopic Cholecystectomy

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-12-01
Completion: 2026-03-31
Conditions
Postoperative Pain Management Laparoscopic Cholecystectomy Ondansetron Postoperative Nausea and Vomiting
Interventions
DRUG
No Results Yet
NCT06624592 | RECRUITING | PHASE3
400 Participants

Sevoflurane/Dexmedetomidine vs. Isoflurane for Pediatric Emergence Delirium

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2024-12-20
Completion: 2026-11-01
Conditions
Delirium on Emergence
Interventions
DRUG
No Results Yet
NCT06623981 | RECRUITING | NA
60 Participants

The Exhale Study: Treating Maternal Depression in an Urban Pediatric Asthma Clinic

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2024-10-15
Completion: 2027-04-30
Conditions
Asthma in Children Depression
Interventions
BEHAVIORAL
No Results Yet
NCT06615050 | RECRUITING | PHASE3
572 Participants

A Study of Tacrolimus/Methotrexate/Ruxolitinib Versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell Transplantation (BMT CTN 2203)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-04-02
Completion: 2031-01-17
Conditions
Graft-versus-host Disease (GVHD)
Interventions
DRUG
No Results Yet
NCT06598371 | RECRUITING | PHASE1/PHASE2
141 Participants

A Phase 1/2 Study of KSQ-004EX, Autologous Tumor Infiltrating Lymphocytes Engineered to Inactivate Genes Encoding SOCS1 and Regnase-1, in Patients With Select Advanced Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2024-11-21
Completion: 2039-08-01
Conditions
Select Advanced Solid Tumors
Interventions
DRUG
No Results Yet
NCT06589713 | RECRUITING | PHASE1
40 Participants

Effect of Renal Impairment on Enpatoran Pharmacokinetics

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2024-09-24
Completion: 2026-04-22
Conditions
Renal Impairment
Interventions
DRUG
No Results Yet
NCT06584929 | NOT_YET_RECRUITING | NA
272 Participants

Rural Smoking Cessation

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2026-02-01
Completion: 2028-10-01
Conditions
Smoking Cessation
Interventions
DRUG
No Results Yet
NCT06579833 | ACTIVE_NOT_RECRUITING | NA
60 Participants

Histotripsy (HistoSonics®) for Liver Tumours

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2024-08-29
Completion: 2027-09-01
Conditions
Liver Tumour
Interventions
RADIATION
No Results Yet
NCT06575998 | RECRUITING | NA
315 Participants

Insomnia in Primary Care

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2024-09-12
Completion: 2026-09-09
Conditions
Insomnia
Interventions
OTHER
No Results Yet
NCT06569537 | RECRUITING | PHASE4
64 Participants

Comparison of Compounded Topical Anesthetics

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2024-10-22
Completion: 2026-01-31
Conditions
Procedural Pain
Interventions
DRUG
No Results Yet
NCT06567873 | COMPLETED
40 Participants

Gastric Ultrasound Assessment for Patients Taking Cannabis

Study Type: OBSERVATIONAL
Last Updated: 2025-12-16
Start Date: 2025-05-09
Completion: 2025-10-13
Conditions
Gastric Ultrasound Point of Care Ultrasound Cannabis Use
Interventions
OTHER
No Results Yet
NCT06567249 | RECRUITING | NA
60 Participants

Intracoronary Hypothermia as a Prevention of Reperfusion Injury in Myocardial Infarction.

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2024-05-05
Completion: 2026-09-30
Conditions
Myocardial Infarction ST-Elevation Myocardial Infarction (STEMI) Reperfusion Injury Microvascular Occlusion
Interventions
PROCEDURE OTHER
No Results Yet
NCT06563102 | ACTIVE_NOT_RECRUITING | PHASE4
101 Participants

Study to Investigate Changes in Airway Inflammation, Symptoms, and Rescue Therapy Utilization With AIRSUPRA Compared to Albuterol as Needed in Adults With Mild Asthma

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2024-09-11
Completion: 2026-02-20
Conditions
Mild Asthma
Interventions
COMBINATION_PRODUCT
No Results Yet
NCT06552416 | RECRUITING | PHASE1
40 Participants

Safety of MT-401-OTS in Patients With Relapsed AML or MDS

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-06-16
Completion: 2029-09-30
Conditions
Acute Myeloid Leukemia, in Relapse MDS
Interventions
DRUG
No Results Yet
NCT06546150 | RECRUITING | PHASE1
30 Participants

RE002 T Cell Injection for the Treatment of KRAS G12D Mutated Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2024-03-01
Completion: 2026-04-01
Conditions
KRAS G12D T Cell Therapy
Interventions
BIOLOGICAL
No Results Yet
NCT06545643 | NOT_YET_RECRUITING | NA
35 Participants

Sleep-Sensitive Seizure Risk Assessment With Wearable EEGs

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2026-05-01
Completion: 2027-06-01
Conditions
Epilepsy Intractable
Interventions
DEVICE
No Results Yet
NCT06529003 | COMPLETED | NA
36 Participants

TENS Unit To Decrease Pain After Laminaria Insertion

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2024-08-14
Completion: 2025-11-05
Conditions
Second Trimester Abortion
Interventions
DEVICE
No Results Yet
NCT06526260 | RECRUITING | NA
80 Participants

Very Brief Exposure: Development of a Novel Exposure Modality for Social Anxiety Disorder in Transition-Age Youth

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2024-08-14
Completion: 2026-07-31
Conditions
Social Anxiety Disorder
Interventions
BEHAVIORAL
No Results Yet
NCT06517875 | RECRUITING | PHASE2
56 Participants

Study of Momelotinib in Combination With Luspatercept in Participants With Transfusion Dependent Myelofibrosis

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-02-28
Completion: 2026-10-14
Conditions
Primary Myelofibrosis Myelofibrosis; Primary Myelofibrosis; Post-polycythemia Vera Myelofibrosis; Post-essential Thrombocythemia Myelofibrosis
Interventions
DRUG
No Results Yet
NCT06515054 | COMPLETED | NA
50 Participants

Isometric Exercise for Hypertension

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2024-07-20
Completion: 2025-09-30
Conditions
Hypertension
Interventions
BEHAVIORAL
No Results Yet
NCT06514508 | RECRUITING | PHASE3
60 Participants

Mobilization of Stem Cells With Motixafortide (BL-8040) in Combination With G-CSF in Multiple Myeloma Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-12-01
Completion: 2026-12-31
Conditions
Multiple Myeloma
Interventions
DRUG
No Results Yet
NCT06510556 | RECRUITING | NA
250 Participants

Feasibility Study of the FARAFLEX Mapping and PFA System

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-02-17
Completion: 2027-02-15
Conditions
Atrial Fibrillation Persistent Atrial Fibrillation Paroxysmal AF
Interventions
DEVICE
No Results Yet
NCT06507306 | RECRUITING | PHASE1
100 Participants

A Study to Investigate the Safety and Efficacy of KQB198 as Monotherapy and in Combination in Participants With Advanced Solid Malignancies

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2024-06-03
Completion: 2026-07-31
Conditions
Solid Tumor, Adult
Interventions
DRUG
No Results Yet
NCT06495450 | RECRUITING | NA
30 Participants

Using Omnidirectional Virtual Reality and Treadmill Training for Chronic Stroke

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2025-04-28
Completion: 2026-08-06
Conditions
Stroke
Interventions
DEVICE BEHAVIORAL
No Results Yet
NCT06494579 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
12 Participants

Lamivudine for Solid Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2024-09-26
Completion: 2026-07-28
Conditions
Relapsed/Refractory Solid Tumors
Interventions
DRUG
No Results Yet
NCT06492759 | NOT_YET_RECRUITING | PHASE2
29 Participants

High Dose Radiation Therapy With Pembrolizumab and Chemotherapy for the Treatment of Patients With PD-L1 Positive Metastatic Triple Negative Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2026-01-31
Completion: 2027-02-12
Conditions
Anatomic Stage IV Breast Cancer AJCC v8 Metastatic Triple-Negative Breast Carcinoma
Interventions
PROCEDURE OTHER RADIATION BIOLOGICAL DRUG
No Results Yet
NCT06488950 | RECRUITING | EARLY_PHASE1
30 Participants

A Study of TIL in Advanced Solid Tumors (DFGD)

Study Type: INTERVENTIONAL
Last Updated: 2025-12-16
Start Date: 2023-04-01
Completion: 2026-06-30
Conditions
Advanced Solid Tumor Tumor Infiltrating Lymphocytes Treatment Side Effects Effects of Immunotherapy
Interventions
BIOLOGICAL
No Results Yet
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