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Clinical Trials

Showing trials with last updates posted in 2025.

NCT06081283 | TERMINATED | PHASE4
5 Participants

Antiseizure Medication in Seizure Networks at Early Acute Brain Injury

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-11-20
Completion: 2024-12-22
Conditions
Brain Injuries, Acute Brain Injuries, Traumatic Brain Ischemia Brain Hypoxia Hypoxia-Ischemia, Brain Heart Arrest Stroke Intracranial Hemorrhages Coma Persistent Vegetative State
Interventions
DRUG
Results Available
NCT06079190 | ACTIVE_NOT_RECRUITING | PHASE2
367 Participants

Efficacy and Safety of GSK4527226 [AL101] in Participants With Early Alzheimer's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-10-20
Completion: 2026-09-30
Conditions
Alzheimer's Disease
Interventions
DRUG OTHER
No Results Yet
NCT06077760 | RECRUITING | PHASE3
868 Participants

A Study of Intismeran Autogene (V940) Plus Pembrolizumab (MK-3475) Versus Placebo Plus Pembrolizumab in Participants With Non-small Cell Lung Cancer (V940-002)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-12-06
Completion: 2030-06-25
Conditions
Non-small Cell Lung Cancer
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT06077162 | ACTIVE_NOT_RECRUITING | NA
67 Participants

Diabetes Nutrition Education and Healthy Food Resource for AIANs With T2D

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-09-01
Completion: 2026-01-01
Conditions
Type 2 Diabetes
Interventions
OTHER
No Results Yet
NCT06072781 | RECRUITING | PHASE3
270 Participants

A Study of Avutometinib (VS-6766) + Defactinib (VS-6063) in Recurrent Low-Grade Serous Ovarian Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-03-18
Completion: 2028-10-15
Conditions
Low Grade Serous Ovarian Cancer
Interventions
DRUG
No Results Yet
NCT06056297 | RECRUITING | PHASE3
176 Participants

A Study of Mavorixafor in Participants With Congenital and Acquired Primary Autoimmune and Idiopathic Chronic Neutropenic Disorders Who Are Experiencing Recurrent and/or Serious Infections

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-06-06
Completion: 2027-09-30
Conditions
Neutropenia
Interventions
DRUG
No Results Yet
NCT06052631 | RECRUITING
16 Participants

Microneurographic Assessment of Peripheral Nerves in Healthy Volunteers and Individuals With Sensory Dysfunction Caused by Inherited Mutations in the PIEZO2 Gene

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2025-11-19
Completion: 2026-12-31
Conditions
PIEZO2-Deficiency Syndrome
No Results Yet
NCT06043154 | RECRUITING | NA
60 Participants

Discovering New Insights Into Anorexia Nervosa: Influence of MicrObial DysbiosiS (DIAMOnDS)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-02-22
Completion: 2028-09-30
Conditions
Anorexia Nervosa
Interventions
OTHER
No Results Yet
NCT06041503 | NOT_YET_RECRUITING | PHASE2
68 Participants

Enfortumab Vedotin With or Without Pembrolizumab in Rare Genitourinary Tumors (E-VIRTUE)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-11-19
Completion: 2027-10-01
Conditions
Adenocarcinoma of the Bladder Squamous Cell Carcinoma of the Bladder Testicular Germ Cell Tumors
Interventions
DRUG
No Results Yet
NCT06028009 | ACTIVE_NOT_RECRUITING | NA
30 Participants

PRP Injections for Genitourinary Syndrome of Menopause

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-03-01
Completion: 2025-12-31
Conditions
PRP Sexual Function Disturbances Genitourinary Syndrome of Menopause Postmenopausal Symptoms Vaginal Atrophy
Interventions
PROCEDURE
No Results Yet
NCT06027593 | COMPLETED | NA
26139 Participants

Using Electronically Derived Automated Reports of Appropriate Antibiotic Use to Inform Stewardship Interventions

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2022-10-18
Completion: 2024-06-30
Conditions
Community-acquired Pneumonia Acute Otitis Media Pharyngitis
Interventions
OTHER
Results Available
NCT06013930 | COMPLETED | NA
55 Participants

Exploring the Efficacy of Treatments for Anxiety and Depression Among College Students

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-07-25
Completion: 2025-04-15
Conditions
Anxiety Depression
Interventions
BEHAVIORAL OTHER
No Results Yet
NCT06011954 | RECRUITING
202 Participants

A Study to Survey Adults in South Korea With Cancer Who Receive PADCEV Injection

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2023-11-01
Completion: 2027-07-31
Conditions
Urothelial Cancer
Interventions
DRUG
No Results Yet
NCT06002126 | ACTIVE_NOT_RECRUITING | NA
1002 Participants

Optimization of Cervical Cancer Screening Among Women Living With HIV in Latin American Countries

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-08-02
Completion: 2025-07-30
Conditions
Cervix Cancer HPV Infection Cervical High Grade Squamous Intraepithelial Lesion HIV Infections
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT05980416 | TERMINATED | PHASE1
88 Participants

Study of EO-3021 in Adult Patients With Solid Tumors Likely to Express CLDN18.2

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-08-10
Completion: 2025-05-07
Conditions
Stomach Neoplasm Gastrointestinal Neoplasms Digestive System Neoplasm Neoplasms by Site Neoplasms
Interventions
DRUG
Results Available
NCT05966038 | RECRUITING
5000 Participants

ALS/MND Natural History Study Data Repository

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2015-04-01
Completion: 2030-12-31
Conditions
ALS PLS MND (Motor Neurone DIsease) Kennedy Disease PMA - Progressive Muscular Atrophy PBP - Progressive Bulbar Palsy
No Results Yet
NCT05952024 | RECRUITING | PHASE2
80 Participants

Study of Acalabrutinib and Rituximab in Untreated Elderly and/or Frail Patients With DLBCL

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-07-16
Completion: 2027-08-24
Conditions
Diffuse Large B-Cell Lymphoma
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT05949021 | ACTIVE_NOT_RECRUITING | PHASE2
30 Participants

OCTANE: Adjuvant Liposomal Doxorubicin and Carboplatin for Early-stage Triple-negative Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-10-07
Completion: 2027-09-30
Conditions
Triple Negative Breast Cancer (TNBC)
Interventions
DRUG
No Results Yet
NCT05947851 | RECRUITING | PHASE3
735 Participants

A Study of Nemtabrutinib Plus Venetoclax vs Venetoclax + Rituximab (VR) in Second-line (2L) + Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL) (MK-1026-010/BELLWAVE-010).

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-08-08
Completion: 2032-06-01
Conditions
Leukemia, Lymphocytic, Chronic, B-Cell Leukemia, Chronic Lymphocytic Small-Cell Lymphoma Lymphoma, Small Lymphocytic CLL SLL
Interventions
DRUG BIOLOGICAL
No Results Yet
NCT05945485 | ACTIVE_NOT_RECRUITING | PHASE1
50 Participants

A Study to Evaluate the Safety and Immunogenicity of Two Doses of DCVC H1 HA mRNA-LNP in Healthy Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-10-16
Completion: 2026-05-26
Conditions
Influenza
Interventions
BIOLOGICAL OTHER
No Results Yet
NCT05917288 | COMPLETED | PHASE1
16 Participants

A Study of Belimumab in Chinese Pediatric Participants With Systemic Lupus Erythematosus

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-07-07
Completion: 2024-10-30
Conditions
Systemic Lupus Erythematosus
Interventions
BIOLOGICAL DRUG
Results Available
NCT05911399 | AVAILABLE

Expanded Access Program for Tiratricol in Patients With Monocarboxylate Transporter 8 Deficiency

Study Type: EXPANDED_ACCESS
Last Updated: 2025-11-14
Conditions
Monocarboxylate Transporter 8 Deficiency Allan-Herndon-Dudley Syndrome
Interventions
DRUG
No Results Yet
NCT05904704 | WITHDRAWN | NA
0 Participants

Oxygen-Enhanced MRI for Generating Hypoxia Maps in Patients With Intracranial Tumors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-04-12
Completion: 2029-03-31
Conditions
Intracranial Neoplasm
Interventions
PROCEDURE
No Results Yet
NCT05897320 | RECRUITING | PHASE3
315 Participants

A Study of Eptinezumab in Pediatric Participants With Episodic Migraine

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-06-08
Completion: 2027-07-06
Conditions
Episodic Migraine
Interventions
DRUG
No Results Yet
NCT05894473 | COMPLETED | NA
30 Participants

Effects of Telerehabilitation Based Motor and Cognitive Dual Task Exercises in Patients With Parkinson's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-05-30
Completion: 2023-07-14
Conditions
Parkinson Disease
Interventions
OTHER
No Results Yet
NCT05890677 | RECRUITING | NA
280 Participants

The LYMPH Trial - Microsurgical Versus Conservative Treatment of Chronic Breast Cancer Associated Lymphedema

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-07-14
Completion: 2027-09-30
Conditions
Lymphedema, Breast Cancer
Interventions
PROCEDURE
No Results Yet
NCT05883163 | RECRUITING | NA
40 Participants

STIMIT Activator 1 IDE Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-01-24
Completion: 2026-04-30
Conditions
Diaphragm Issues
Interventions
DEVICE
No Results Yet
NCT05859334 | RECRUITING | PHASE2
35 Participants

Testing the Anti-cancer Drug Erdafitinib for Brain Cancers That Have Returned or Progressed Following Treatment

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-01-04
Completion: 2026-10-23
Conditions
Recurrent Glioma Recurrent WHO Grade 2 Glioma Recurrent WHO Grade 3 Glioma Recurrent WHO Grade 4 Glioma
Interventions
PROCEDURE DRUG
No Results Yet
NCT05848557 | RECRUITING | NA
6000 Participants

mSaada: A Mobile Health Tool

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-02-19
Completion: 2027-06-30
Conditions
Cervical Cancer HPV mHealth
Interventions
BEHAVIORAL
No Results Yet
NCT05845307 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1
33 Participants

Randomized Pre-surgical Window-of-Opportunity Trial of TTI-101 in Patients With Stage II-IV Resectable HPV-negative Squamous Cell Carcinoma of the Head and Neck

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2025-06-20
Completion: 2026-06-01
Conditions
Squamous Cell Carcinoma of Head and Neck
Interventions
DRUG
No Results Yet
NCT05843318 | RECRUITING | NA
375 Participants

Water Intake and Weight Control in Older Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-11-13
Completion: 2027-12-20
Conditions
Overweight and Obesity
Interventions
BEHAVIORAL
No Results Yet
NCT05840159 | RECRUITING | PHASE4
664 Participants

A Study of Doxycycline to Treat Chlamydial Infection

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-01-19
Completion: 2026-02-28
Conditions
Chlamydial Infection
Interventions
DRUG OTHER
No Results Yet
NCT05839379 | RECRUITING
350 Participants

Targeted Pediatric High-Grade Glioma Therapy

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2024-08-02
Completion: 2029-08-28
Conditions
High Grade Glioma Diffuse Intrinsic Pontine Glioma Anaplastic Astrocytoma Glioblastoma Glioblastoma Multiforme Diffuse Midline Glioma, H3 K27M-Mutant Metastatic Brain Tumor WHO Grade III Glioma WHO Grade IV Glioma
No Results Yet
NCT05820087 | ACTIVE_NOT_RECRUITING | NA
67 Participants

The HistoSonics Edison™ System for Treatment of Primary Solid Renal Tumors Using Histotripsy (#HOPE4KIDNEY)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-01-04
Completion: 2025-09-04
Conditions
Renal Cancer Tumor, Solid Kidney Cancer Tumor Tumor, Benign
Interventions
DEVICE
No Results Yet
NCT05814627 | ACTIVE_NOT_RECRUITING | PHASE3
487 Participants

Study to Assess Change in Disease Activity and Adverse Events of Oral Upadacitinib Compared to Subcutaneous Adalimumab in Adult Participants With Moderate to Severe Rheumatoid Arthritis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-06-15
Completion: 2026-07-31
Conditions
Rheumatoid Arthritis
Interventions
DRUG
No Results Yet
NCT05791981 | ACTIVE_NOT_RECRUITING | NA
100 Participants

Multi-site Feasibility and Acceptability of a Faith-based Mind-body Intervention for Black Adults

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-03-26
Completion: 2026-01-31
Conditions
Psychosocial Mind-body
Interventions
BEHAVIORAL DEVICE
No Results Yet
NCT05789589 | RECRUITING | PHASE1/PHASE2
46 Participants

Effect of Azeliragon Combined With Stereotactic Radiation Therapy in Patients With Brain Metastases

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-11-17
Completion: 2027-03-16
Conditions
Cancer Metastasis Metastatic Cancer Brain Metastases Brain Metastases, Adult
Interventions
RADIATION DRUG
No Results Yet
NCT05787795 | RECRUITING
1000 Participants

Identifying and Characterizing Preclinical MS

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2022-06-21
Completion: 2032-06-30
Conditions
Multiple Sclerosis
Interventions
OTHER
No Results Yet
NCT05783323 | RECRUITING | PHASE2
13 Participants

Larotrectinib to Enhance RAI Avidity in Differentiated Thyroid Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2024-02-14
Completion: 2026-10-01
Conditions
Differentiated Thyroid Cancer Pediatric Cancer Cancer Cancer, Thyroid
Interventions
DRUG RADIATION
No Results Yet
NCT05782907 | RECRUITING | PHASE3
110 Participants

Study to Assess Adverse Events, Change in Disease Activity, and How Oral Upadacitinib Moves Through the Body of Pediatric Participants With Moderately to Severely Active Ulcerative Colitis.

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2023-11-06
Completion: 2028-08-31
Conditions
Ulcerative Colitis
Interventions
DRUG
No Results Yet
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