Clinical Trials

Showing trials with last updates posted in 2025.

NCT03839524 | COMPLETED | PHASE1
64 Participants

A Trial Evaluating TG4050 in Ovarian Carcinoma.

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2019-12-09
Completion: 2024-10-08
Conditions
Ovarian Carcinoma Fallopian Tube Cancer Peritoneal Carcinoma
Interventions
DRUG
NCT03830918 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
59 Participants

Niraparib, Temozolomide and Atezolizumab in Treating Patients With Advanced Solid Tumors and Extensive-Stage Small Cell Lung Cancer With a Complete or Partial Response to Platinum-Based First-Line Chemotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2019-03-06
Completion: 2026-01-03
Conditions
Advanced Malignant Solid Neoplasm Extensive Stage Lung Small Cell Carcinoma Stage III Lung Cancer AJCC v8 Stage IIIA Lung Cancer AJCC v8 Stage IIIB Lung Cancer AJCC v8 Stage IIIC Lung Cancer AJCC v8 Stage IV Lung Cancer AJCC v8 Stage IVA Lung Cancer AJCC v8 Stage IVB Lung Cancer AJCC v8
Interventions
BIOLOGICAL DRUG OTHER
No Results Yet
NCT03828994 | ACTIVE_NOT_RECRUITING | NA
150 Participants

Technology Based Community Health Nursing(TECH-N) to Prevent Recurrent STIs After PID II

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2019-02-10
Completion: 2026-12-31
Conditions
Pelvic Inflammatory Disease
Interventions
BEHAVIORAL
No Results Yet
NCT03819140 | COMPLETED | PHASE4
51 Participants

Continuous Versus Cyclical OCP Use in PCOS

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2019-04-01
Completion: 2022-10-16
Conditions
Polycystic Ovary Syndrome
Interventions
DRUG
NCT03816683 | COMPLETED
227 Participants

A Disease Registry of Patients With Mantle Cell Lymphoma

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2019-04-01
Completion: 2024-03-18
Conditions
Mantle Cell Lymphoma
No Results Yet
NCT03746080 | COMPLETED | PHASE2
21 Participants

Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With Glioblastoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2018-12-04
Completion: 2022-05-31
Conditions
Glioblastoma Glioblastoma With Primitive Neuronal Component Gliosarcoma Malignant Glioma Oligodendroglial Component Present
Interventions
DRUG RADIATION
NCT03712943 | COMPLETED | PHASE1
52 Participants

Regorafenib and Nivolumab in Mismatch Repair (MMR) Refractory Colorectal Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2018-10-23
Completion: 2021-09-01
Conditions
Colorectal Cancer Metastatic Colorectal Cancer Colon Cancer
Interventions
DRUG
No Results Yet
NCT03695276 | COMPLETED | NA
328 Participants

Pulmonary Specialist-Health Coach Consult Model Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2020-10-20
Completion: 2024-10-04
Conditions
COPD Asthma
Interventions
BEHAVIORAL
NCT03675412 | RECRUITING | NA
80 Participants

Caffeine Consumption in Glaucoma Patients and Healthy Subjects

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2018-12-30
Completion: 2026-12-31
Conditions
Glaucoma, Primary Open Angle
Interventions
DIETARY_SUPPLEMENT
No Results Yet
NCT03674437 | ACTIVE_NOT_RECRUITING
441 Participants

Evaluation of an Online, Remote Cognitive Battery for Use in Cancer Survivorship

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2018-09-11
Completion: 2026-09-30
Conditions
Breast Cancer Survivors
Interventions
BEHAVIORAL
No Results Yet
NCT03654053 | ACTIVE_NOT_RECRUITING | PHASE3
142 Participants

Multi-Center Study of the Effects of Simvastatin on Hepatic Decompensation and Death in Subjects Presenting With High-Risk Compensated Cirrhosis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2020-10-02
Completion: 2025-12-31
Conditions
Cirrhosis
Interventions
DRUG
No Results Yet
NCT03647306 | ACTIVE_NOT_RECRUITING | NA
200 Participants

Behavioral Chronotype: Impact on Sleep and Metabolism

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2018-02-02
Completion: 2023-03-13
Conditions
Type2 Diabetes Mellitus Cardiovascular Diseases
Interventions
BEHAVIORAL
No Results Yet
NCT03611738 | ACTIVE_NOT_RECRUITING | PHASE1
21 Participants

Ceritinib Plus Docetaxel in ALK-Negative, EGFR WT Advanced NSCLC

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2019-02-01
Completion: 2025-04-28
Conditions
Non-small Cell Lung Cancer Lung Cancer Non-small Cell Lung Cancer Metastatic Non-small Cell Lung Cancer Stage IIIB Stage IV Non-small Cell Lung Cancer EGFR Negative Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT03596645 | ACTIVE_NOT_RECRUITING | PHASE3
84 Participants

A Study to Assess the Efficacy and Safety of Golimumab in Pediatric Participants With Moderately to Severely Active Ulcerative Colitis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2018-10-29
Completion: 2023-11-21
Conditions
Colitis, Ulcerative
Interventions
DRUG
NCT03578003 | RECRUITING | NA
200 Participants

Morning Bright Light to Improve Sleep Quality in Veterans

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2017-08-02
Completion: 2026-12-01
Conditions
Brain Injuries, Traumatic Post-traumatic Stress Disorder
Interventions
OTHER
No Results Yet
NCT03539705 | RECRUITING
6000 Participants

Food Allergy Registry at a Single Site

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2018-01-05
Completion: 2028-05-31
Conditions
Allergy and Asthma
Interventions
OTHER
No Results Yet
NCT03537963 | COMPLETED | NA
30 Participants

Improving Sleep in BMT Survivors

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2018-05-15
Completion: 2019-06-29
Conditions
Sleep Disturbance Sleep Disorder
Interventions
OTHER
No Results Yet
NCT03523585 | ACTIVE_NOT_RECRUITING | PHASE3
608 Participants

DS-8201a in Pre-treated HER2 Breast Cancer That Cannot be Surgically Removed or Has Spread [DESTINY-Breast02]

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2018-08-01
Completion: 2022-06-30
Conditions
Breast Cancer
Interventions
DRUG
NCT03519178 | TERMINATED | PHASE1/PHASE2
155 Participants

A Study of PF-06873600 in People With Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2018-03-07
Completion: 2023-04-05
Conditions
HR+ HER2- Metastatic Breast Cancer, Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Cancer, Triple Negative Breast Cancer, Male Breast Cancer
Interventions
DRUG
NCT03485417 | COMPLETED | PHASE2/PHASE3
165 Participants

Substance Misuse To Psychosis for Stimulants

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2019-06-01
Completion: 2024-05-31
Conditions
Stimulant Use With Stimulant-Induced Psychotic Disorder (Diagnosis) Schizophrenia and Related Disorders Stimulant Dependence Stimulant Abuse Pharmacotherapy
Interventions
DRUG OTHER
No Results Yet
NCT03477604 | ACTIVE_NOT_RECRUITING | NA
177 Participants

A Clinical Evaluation of the MicroSTent® PeripherAl Vascular SteNt in Subjects With Arterial Disease Below the Knee (STAND)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2020-03-31
Completion: 2024-12-05
Conditions
Peripheral Arterial Disease
Interventions
DEVICE
No Results Yet
NCT03460977 | RECRUITING | PHASE1
433 Participants

A Study of Mevrometostat for Treatment of Relapsed/Refractory SCLC, Castration Resistant Prostate Cancer, and Follicular Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2018-04-17
Completion: 2028-05-01
Conditions
Metastatic Castration Resistant Prostate Cancer (mCRPC) Small Cell Lung Cancer (SCLC) Follicular Lymphoma (FL)
Interventions
DRUG
No Results Yet
NCT03395210 | ACTIVE_NOT_RECRUITING | PHASE2
86 Participants

A Study of Rilzabrutinib in Adult Patients With Immune Thrombocytopenia (ITP)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2018-03-22
Completion: 2023-01-31
Conditions
Immune Thrombocytopenia
Interventions
DRUG
NCT03387553 | ACTIVE_NOT_RECRUITING | EARLY_PHASE1
31 Participants

HER2 Directed Dendritic Cell Vaccine During Neoadjuvant Therapy of HER2+Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2018-06-06
Completion: 2026-08-29
Conditions
Breast Cancer Breast Cancer Female Breast Cancer, Male Invasive Breast Cancer HER2-positive Breast Cancer HER2 Positive Breast Carcinoma Stage II Breast Cancer Stage III Breast Cancer
Interventions
DRUG PROCEDURE BIOLOGICAL
No Results Yet
NCT03330821 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
53 Participants

Pevonedistat, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2018-04-18
Completion: 2026-10-13
Conditions
Acute Myeloid Leukemia Arising From Previous Myelodysplastic Syndrome Acute Myeloid Leukemia With Myelodysplasia-Related Changes Therapy-Related Acute Myeloid Leukemia
Interventions
DRUG OTHER
No Results Yet
NCT03326921 | RECRUITING | PHASE1
24 Participants

HA-1 T TCR T Cell Immunotherapy for the Treatment of Patients With Relapsed or Refractory Acute Leukemia After Donor Stem Cell Transplant

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2018-02-23
Completion: 2027-10-16
Conditions
Juvenile Myelomonocytic Leukemia Recurrent Acute Biphenotypic Leukemia Recurrent Acute Undifferentiated Leukemia Recurrent Childhood Acute Lymphoblastic Leukemia Recurrent Childhood Acute Myeloid Leukemia Refractory Acute Lymphoblastic Leukemia Refractory Adult Acute Lymphoblastic Leukemia Blast Phase Chronic Myeloid Leukemia, BCR-ABL1 Positive Recurrent Blastic Plasmacytoid Dendritic Cell Neoplasm Recurrent Myelodysplastic Syndrome Refractory Blastic Plasmacytoid Dendritic Cell Neoplasm Refractory Myelodysplastic Syndrome Acute Undifferentiated Leukemia Mixed Phenotype Acute Leukemia Recurrent Chronic Myeloid Leukemia, BCR-ABL1 Positive Refractory Chronic Myeloid Leukemia, BCR-ABL1 Positive Recurrent Acute Lymphoblastic Leukemia Recurrent Acute Myeloid Leukemia Myelodysplastic Syndrome Acute Myeloid Leukemia Acute Lymphoblastic Leukemia Acute Biphenotypic Leukemia Chronic Myeloid Leukemia Chronic Myelomonocytic Leukemia Minimal Residual Disease Recurrent Chronic Myelomonocytic Leukemia Recurrent Mixed Phenotype Acute Leukemia Leukemia Chronic Myeloid Leukemia, BCR-ABL1 Positive
Interventions
BIOLOGICAL PROCEDURE
No Results Yet
NCT03293030 | COMPLETED | PHASE4
17 Participants

Immunogenetic Profiling of Dupilumab for the Treatment of Atopic Dermatitis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2018-10-22
Completion: 2023-02-23
Conditions
Atopic Dermatitis Atopic Dermatitis Eczema Eczema Atopic Dermatitis and Related Conditions
Interventions
DRUG
NCT03257033 | RECRUITING | PHASE3
190 Participants

Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2018-03-12
Completion: 2026-06-30
Conditions
Locally Advanced Pancreatic Cancer
Interventions
DRUG DEVICE
No Results Yet
NCT03256539 | TERMINATED | NA
15 Participants

Napping, Sleep, Cognitive Decline and Risk of Alzheimer's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2021-08-12
Completion: 2024-01-31
Conditions
Sleep Alzheimer Disease Cognitive Impairment Aging CBT
Interventions
BEHAVIORAL
NCT03250247 | ACTIVE_NOT_RECRUITING | NA
250 Participants

Chronic Venous Thrombosis: Relief With Adjunctive Catheter-Directed Therapy (The C-TRACT Trial)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2018-07-02
Completion: 2026-01-30
Conditions
Deep Vein Thrombosis Venous Stasis Venous Insufficiency Venous Leg Ulcer Venous Reflux Post Thrombotic Syndrome
Interventions
DEVICE
No Results Yet
NCT03249350 | COMPLETED | NA
129 Participants

Enhancing Adolescent Substance Abuse Treatment

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2018-04-23
Completion: 2024-03-29
Conditions
Substance Use Disorders
Interventions
BEHAVIORAL
NCT03192436 | RECRUITING | NA
80 Participants

Electrophysiological Source Imaging Guided Transcranial Focused Ultrasound

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2018-09-01
Completion: 2030-06-30
Conditions
Healthy
Interventions
DEVICE
No Results Yet
NCT03113500 | ACTIVE_NOT_RECRUITING | PHASE2
48 Participants

Brentuximab Vedotin and Combination Chemotherapy in Treating Patients With CD30-Positive Peripheral T-cell Lymphoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2017-05-25
Completion: 2021-07-16
Conditions
Adult T-Cell Leukemia/Lymphoma Anaplastic Large Cell Lymphoma, ALK-Negative Anaplastic Large Cell Lymphoma, ALK-Positive Angioimmunoblastic T-Cell Lymphoma Ann Arbor Stage II Noncutaneous Anaplastic Large Cell Lymphoma Ann Arbor Stage III Noncutaneous Anaplastic Large Cell Lymphoma Ann Arbor Stage IV Noncutaneous Anaplastic Large Cell Lymphoma Enteropathy-Associated T-Cell Lymphoma Hepatosplenic T-Cell Lymphoma Mature T-Cell and NK-Cell Non-Hodgkin Lymphoma Peripheral T-Cell Lymphoma, Not Otherwise Specified
Interventions
DRUG OTHER
NCT03109288 | RECRUITING | PHASE1/PHASE2
250 Participants

Targeting Residual Activity By Precision, Biomarker-Guided Combination Therapies of Multiple Sclerosis (TRAP-MS)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2017-08-11
Completion: 2026-01-01
Conditions
Multiple Sclerosis
Interventions
DRUG
No Results Yet
NCT03049462 | RECRUITING | PHASE1
100 Participants

The Physiological Responses and Adaptation of Brown Adipose Tissue to Chronic Treatment With Beta3-Adrenergic Receptor Agonists

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2017-03-13
Completion: 2026-09-30
Conditions
Polycystic Ovary Syndrome
Interventions
DRUG OTHER
No Results Yet
NCT02997254 | RECRUITING
1000 Participants

COMparison of Physiological Algorithms for Real-time Evaluation of Atrial Fibrillation

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2016-12-01
Completion: 2026-12-31
Conditions
Atrial Fibrillation Abnormal Heart Rhythms
No Results Yet
NCT02939300 | COMPLETED | PHASE2
18 Participants

Ipilimumab and Nivolumab in Leptomeningeal Metastases

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2018-02-15
Completion: 2021-07-22
Conditions
Leptomeningeal Carcinomatosis
Interventions
DRUG
NCT02936102 | TERMINATED | PHASE1
154 Participants

A Study of FAZ053 Single Agent and in Combination With PDR001 in Patients With Advanced Malignancies.

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2016-10-20
Completion: 2024-11-22
Conditions
Advanced Solid Tumors Triple Negative Breast Cancer Chordoma and Alveolar Soft Part Sarcoma
Interventions
DRUG
No Results Yet
NCT02928289 | TERMINATED | NA
29 Participants

Safety and Effectiveness of the Sight Sciences VISCO™360 Versus SLT in Primary Open Angle Glaucoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-14
Start Date: 2017-01-23
Completion: 2019-01-17
Conditions
Open-Angle Glaucoma
Interventions
DEVICE
NCT02910557 | ACTIVE_NOT_RECRUITING
187 Participants

Postmarketing Prospective Study of Melanoma Patients Treated With IMLYGIC® to Characterize Risk of Herpetic Infection

Study Type: OBSERVATIONAL
Last Updated: 2025-11-14
Start Date: 2017-08-10
Completion: 2026-01-30
Conditions
Melanoma Herpetic Infection
No Results Yet
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