Morning Bright Light to Improve Sleep Quality in Veterans

NCT ID: NCT03578003

Last Updated: 2025-11-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

200 participants

Study Classification

INTERVENTIONAL

Study Start Date

2017-08-02

Study Completion Date

2026-12-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

One of the principal complicating factors associated with traumatic brain injury (TBI) is sleep-wake disturbances (e.g., insomnia, excessive daytime sleepiness, and circadian rhythm sleep disorders). Morning bright light therapy (MBLT) has been shown to improve sleep quality in a variety of conditions, but little has been done investigating the utility of MBLT in improving sleep in Veterans with TBI. This proposal aims to determine the effect of MBLT on sleep quality in Veterans with TBI. Veterans with and without TBI will be recruited from the VA Portland Health Care System. Baseline questionnaires and 7 days of actigraphy will be collected prior to engaging in 60 minutes of MBLT daily for 4 weeks, during which actigraphy will also be collected continuously. Post-MBLT questionnaire data will be collected, and follow-up questionnaire data will be collected at 3 months post-MBLT.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Brain Injuries, Traumatic Post-traumatic Stress Disorder

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

Sleep Bright Light

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Morning Bright Light Therapy

Subjects who engage in morning bight light therapy

Group Type EXPERIMENTAL

Morning Bright Light Therapy

Intervention Type OTHER

60 minutes of bright light therapy (10,000 lux) received within 90 minutes of waking

Control

Subjects who do not engage in morning bright light therapy

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Morning Bright Light Therapy

60 minutes of bright light therapy (10,000 lux) received within 90 minutes of waking

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Veterans

Exclusion Criteria

* History of bipolar disorder
* History of macular degeneration
* Non-English speaking
* Decisionally impaired
* Currently using a light box
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Oregon Health and Science University

OTHER

Sponsor Role collaborator

Portland VA Medical Center

FED

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Miranda M Lim

Staff Physician and Assistant Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Miranda M Lim, MD, PhD

Role: PRINCIPAL_INVESTIGATOR

Portland VA Medical Center

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

VA Portland Health Care System

Portand, Oregon, United States

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

United States

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Miranda M Lim, MD, PhD

Role: CONTACT

Phone: 503-220-8262

Email: [email protected]

Jonathan E Elliott, PhD

Role: CONTACT

Phone: 503-220-8262

Email: [email protected]

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Miranda M Lim, MD, PhD

Role: primary

References

Explore related publications, articles, or registry entries linked to this study.

Elliott JE, McBride AA, Balba NM, Thomas SV, Pattinson CL, Morasco BJ, Wilkerson A, Gill JM, Lim MM. Feasibility and preliminary efficacy for morning bright light therapy to improve sleep and plasma biomarkers in US Veterans with TBI. A prospective, open-label, single-arm trial. PLoS One. 2022 Apr 14;17(4):e0262955. doi: 10.1371/journal.pone.0262955. eCollection 2022.

Reference Type DERIVED
PMID: 35421086 (View on PubMed)

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

4085

Identifier Type: -

Identifier Source: org_study_id