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Clinical Trials

NCT06123195 | RECRUITING | NA
40 Participants

Effects of Constipation Treatment in Chronic Kidney Disease: A Pilot Feasibility Trial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-01
Completion: 2025-11-17
Conditions
Chronic Kidney Disease Constipation
Interventions
OTHER
No Results Yet
NCT06122935 | COMPLETED | NA
6735 Participants

Evaluation of the Aurora Xi New Nomogram Software 2.0

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-11-27
Completion: 2024-04-19
Conditions
Apheresis Related Hypotension
Interventions
DEVICE
Results Available
NCT06121297 | RECRUITING | PHASE1/PHASE2
12 Participants

RESET-SLE: A Phase 1/2 Open-Label Study to Evaluate the Safety and Efficacy of CABA-201 in Subjects With Active Systemic Lupus Erythematosus

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-16
Completion: 2027-12-31
Conditions
Systemic Lupus Erythematosus Lupus Nephritis
Interventions
BIOLOGICAL
No Results Yet
NCT06117891 | RECRUITING
300 Participants

An Observational Study to Learn More About How Well a Treatment Works When Given After Treatment With Atezolizumab and Bevacizumab or Another Similar Combination of Drugs in Adults With Liver Cancer That Cannot be Treated With Surgery

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2023-11-27
Completion: 2026-11-27
Conditions
Unresectable Hepatocellular Carcinoma
Interventions
DRUG
No Results Yet
NCT06112418 | RECRUITING | NA
7500 Participants

A Randomized Comparison of Stage-Based Care Versus Risk Factor-Based Care for Prevention of Cardiovascular Events

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-03-06
Completion: 2029-03-05
Conditions
Diabetes Mellitus, Type 2 PreDiabetes Metabolic Syndrome
Interventions
DEVICE
No Results Yet
NCT06109181 | ACTIVE_NOT_RECRUITING | PHASE1/PHASE2
10 Participants

Gene Therapy for ACM Due to a PKP2 Pathogenic Variant

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-29
Completion: 2026-12-31
Conditions
Arrhythmogenic Cardiomyopathy PKP2-ACM PKP2-ARVC
Interventions
GENETIC
No Results Yet
NCT06098079 | RECRUITING | PHASE4
8600 Participants

Effect of Naltrexone Hydrochloride ER and Bupropion Hydrochloride ER Combination (Contraveยฎ/Mysimbaยฎ) on Major Adverse Cardiovascular Events (MACE)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-01-03
Completion: 2029-01-31
Conditions
Obesity
Interventions
DRUG
No Results Yet
NCT06095505 | RECRUITING | PHASE2
80 Participants

A Study of Alisertib in Patients With Extensive Stage Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-08
Completion: 2027-04-30
Conditions
Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT06087640 | RECRUITING | PHASE3
35800 Participants

A Clinical Study to Evaluate the Efficacy, Safety and Immunogenicity of an Adjuvanted Influenza Vaccine Compared to a Non-adjuvanted Influenza Vaccine in Adults โ‰ฅ65 Years of Age

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-10-23
Completion: 2026-11-30
Conditions
Influenza, Human
Interventions
BIOLOGICAL
No Results Yet
NCT06077500 | ACTIVE_NOT_RECRUITING | PHASE1
46 Participants

DAREONแต€แดน-8: A Study to Test How Well Different Doses of BI 764532 in Addition to Standard of Care Are Tolerated by People With Advanced Small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-14
Completion: 2025-12-01
Conditions
Small Cell Lung Carcinoma (SCLC)
Interventions
DRUG
No Results Yet
NCT06074588 | RECRUITING | PHASE3
556 Participants

Sacituzumab Tirumotecan (MK-2870) Versus Chemotherapy in Previously Treated Advanced or Metastatic Nonsquamous Non-small Cell Lung Cancer (NSCLC) With EGFR Mutations or Other Genomic Alterations (MK-2870-004)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-11-12
Completion: 2027-05-10
Conditions
Non-small Cell Lung Cancer (NSCLC)
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT06073821 | ACTIVE_NOT_RECRUITING | PHASE3
652 Participants

Study of Sonrotoclax (BGB-11417) Plus Zanubrutinib (BGB-3111) Compared With Venetoclax Plus Obinutuzumab in Participants With Chronic Lymphocytic Leukemia (CLL)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-11-11
Completion: 2032-02-29
Conditions
CLL
Interventions
DRUG
No Results Yet
NCT06067347 | RECRUITING
1200 Participants

A Global Study of the PETAL Consortium

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2024-01-05
Completion: 2028-01-31
Conditions
T-Cell and NK-Cell Neoplasm
No Results Yet
NCT06064097 | RECRUITING | PHASE2
50 Participants

A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-06-25
Completion: 2026-12-31
Conditions
Stage II Nasopharyngeal Carcinoma AJCC v8 Stage III Nasopharyngeal Carcinoma AJCC v8 Stage IV Nasopharyngeal Carcinoma AJCC v8
Interventions
PROCEDURE DRUG OTHER BIOLOGICAL RADIATION
No Results Yet
NCT06062368 | RECRUITING | NA
100 Participants

Reducing Vertigo Associated With MRI Machines

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-01-15
Completion: 2027-01-01
Conditions
Vertigo Dizziness
Interventions
BEHAVIORAL
No Results Yet
NCT06059586 | RECRUITING | NA
20 Participants

Pre-Rehabilitation for Female Patients Undergoing Pelvic Radiotherapy

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-01-16
Completion: 2026-01-31
Conditions
Dyspareunia Pelvic Pain Sexual Dysfunction Radiation Toxicity
Interventions
BEHAVIORAL DEVICE
No Results Yet
NCT06058793 | ACTIVE_NOT_RECRUITING | PHASE3
138 Participants

Brightline-4: A Study to Test How Well Brigimadlin is Tolerated by People With a Type of Cancer Called Dedifferentiated Liposarcoma

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-12-13
Completion: 2025-11-21
Conditions
Liposarcoma, Dedifferentiated
Interventions
DRUG
No Results Yet
NCT06058377 | RECRUITING | PHASE3
3680 Participants

Adding an Immunotherapy Drug, MEDI4736 (Durvalumab), to the Usual Chemotherapy Treatment (Paclitaxel, Cyclophosphamide, and Doxorubicin) for Stage II-III Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-11-27
Completion: 2026-05-31
Conditions
Anatomic Stage II Breast Cancer AJCC v8 Anatomic Stage III Breast Cancer AJCC v8 HER2-Negative Breast Carcinoma Hormone Receptor-Positive Breast Carcinoma
Interventions
PROCEDURE DRUG BIOLOGICAL OTHER
No Results Yet
NCT06054412 | ACTIVE_NOT_RECRUITING | NA
20 Participants

An Adjunctive Neurofeedback Training Program to Enhance Wellness Among Trauma-Exposed Postpartum Mothers

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-03-03
Completion: 2025-09-01
Conditions
Well-Being, Psychological Dissociation Maternal Care Patterns Maternal Behavior Maternal Distress Mood Disturbance Emotional Regulation Post Traumatic Stress Disorder
Interventions
DEVICE
No Results Yet
NCT06038838 | RECRUITING | NA
30 Participants

Feasibility Study of the Tioga TMVR System

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-04-01
Completion: 2026-07-01
Conditions
Mitral Regurgitation
Interventions
DEVICE
No Results Yet
NCT06034405 | RECRUITING
1663 Participants

Analysis of Lumbar Spine Stenosis Specimens for Identification of Transthyretin Cardiac Amyloidosis

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2023-09-19
Completion: 2026-05-31
Conditions
Lumbar Spinal Stenosis Cardiac Amyloidosis ATTR Amyloidosis Wild Type ATTR Gene Mutation ATTRV122I Amyloidosis Cardiomyopathy, Hypertrophic
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT06021704 | NOT_YET_RECRUITING | NA
120 Participants

The Care for America's Aging Study

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2025-12-01
Completion: 2027-11-30
Conditions
Cognitive Impairment Dementia With Behavioral Disturbance Dementia Alzheimer Disease
Interventions
BEHAVIORAL
No Results Yet
NCT06012240 | RECRUITING | PHASE3
1500 Participants

A Study to Evaluate the Safety and Effectiveness of Upadacitinib Tablets in Adult and Adolescent Participants With Severe Alopecia Areata

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-10-11
Completion: 2028-01-31
Conditions
Alopecia Areata
Interventions
DRUG
No Results Yet
NCT06011239 | COMPLETED | NA
614 Participants

Family Teams: A Study to Promote Team Collaboration in Family Medicine Clinics

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-09-08
Completion: 2025-10-20
Conditions
Patient Care Team Psychological Well-Being Occupational Burnout
Interventions
BEHAVIORAL
No Results Yet
NCT06002165 | ENROLLING_BY_INVITATION | NA
4000 Participants

Testing Implementation Strategies to Support Clinic Fidelity to an Outpatient Hypertension Bundle

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-10-04
Completion: 2027-06-30
Conditions
Pregnancy Related Hypertension
Interventions
BEHAVIORAL
No Results Yet
NCT05975983 | RECRUITING | PHASE2
40 Participants

Study Evaluating INS018_055 Administered Orally to Subjects With Idiopathic Pulmonary Fibrosis

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-02-08
Completion: 2026-02-28
Conditions
Idiopathic Pulmonary Fibrosis (IPF)
Interventions
DRUG
No Results Yet
NCT05975593 | RECRUITING | NA
60 Participants

MicroEnvironment Tumor Effects of Radiotherapy - Comprehensive Radiobiology Assessment TRial

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-01-11
Completion: 2032-12-31
Conditions
Locally Advanced Cervical Carcinoma Locally Advanced Cervical Cancer Locally Advanced Pancreas Cancer Locally Advanced Pancreatic Carcinoma Locally Advanced Pancreatic Cancer Cervical Cancer Pancreas Cancer Pancreatic Cancer Cancer of the Cervix Cancer of the Pancreas
Interventions
OTHER DEVICE
No Results Yet
NCT05970406 | ENROLLING_BY_INVITATION | NA
60 Participants

High Intensity Dysphagia Rehab for Acute Ischemic Stroke Patients

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-11-30
Completion: 2026-11-30
Conditions
Dysphagia Following Cerebrovascular Accident
Interventions
OTHER
No Results Yet
NCT05968638 | ACTIVE_NOT_RECRUITING | NA
50 Participants

Ketogenic Diet in People With Schizophrenia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-09-01
Completion: 2026-08-01
Conditions
Schizophrenia Schizo Affective Disorder
Interventions
OTHER
No Results Yet
NCT05965713 | ACTIVE_NOT_RECRUITING | NA
80 Participants

National Fully Remote Use of IpsiHand Device in Hemiparetic Stroke

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-10-01
Completion: 2025-09-12
Conditions
Stroke Hemiparesis Spasticity as Sequela of Stroke Brain Computer Interface
Interventions
DEVICE OTHER
No Results Yet
NCT05952037 | RECRUITING | PHASE2
105 Participants

A Study to Investigate Efficacy and Safety of BCL2 Inhibitor Sonrotoclax as Monotherapy and in Combination With Zanubrutinib in Adults With Waldenstrรถm Macroglobulinemia

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-09-28
Completion: 2026-12-31
Conditions
Waldenstrom Macroglobulinemia Waldenstrom's Macroglobulinemia Recurrent Waldenstrom's Macroglobulinemia Refractory
Interventions
DRUG
No Results Yet
NCT05949047 | RECRUITING | NA
270 Participants

Smartphone-based Cognitive Emotion Regulation Training for Unpaid Primary Caregivers of Persons With Alzheimer's Disease

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-09-14
Completion: 2026-11-30
Conditions
Caregivers Emotions Emotion Regulation Stress Psychological Psychophysiology
Interventions
BEHAVIORAL
No Results Yet
NCT05948943 | RECRUITING | PHASE2/PHASE3
232 Participants

Alpelisib in Pediatric and Adult Patients With Lymphatic Malformations Associated With a PIK3CA Mutation.

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-11-24
Completion: 2028-05-31
Conditions
Lymphatic Malformations
Interventions
DRUG
No Results Yet
NCT05946941 | RECRUITING | PHASE3
756 Participants

A Study to Evaluate the Efficacy and Safety of Deucravacitinib in Adults With Active Sjรถgren's Syndrome

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-09-11
Completion: 2026-11-18
Conditions
Sjรถgren's Syndrome
Interventions
DRUG OTHER
No Results Yet
NCT05939414 | RECRUITING | PHASE3
450 Participants

An Open-label Study Comparing Lutetium (177Lu) Vipivotide Tetraxetan Versus Observation in PSMA Positive OMPC.

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-03-12
Completion: 2028-04-25
Conditions
Oligometastatic Prostate Cancer (OMPC)
Interventions
DRUG
No Results Yet
NCT05936996 | COMPLETED
258 Participants

Prospective Clinical Registry Evaluating Contemporary MANTA Outcomes

Study Type: OBSERVATIONAL
Last Updated: 2025-11-12
Start Date: 2023-11-15
Completion: 2025-06-20
Conditions
Femoral Arteriotomy Closure
Interventions
DEVICE
No Results Yet
NCT05935748 | TERMINATED | PHASE2
18 Participants

Ph2 Study NKT2152 With Palbociclib & Sasanlimab in Subjects With Advanced Clear Cell Renal Cell Carcinoma (ccRcc)

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-07-28
Completion: 2025-06-30
Conditions
ccRCC Clear Cell Renal Cell Carcinoma Kidney Cancer Kidney Neoplasms Renal Cancer Renal Neoplasms Recurrent Renal Cell Carcinoma Metastatic Renal Cell Carcinoma Refractory Renal Cell Carcinoma Advanced Renal Cell Carcinoma Carcinoma Neoplasms Carcinoma, Renal Cell Neoplasms, Glandular and Epithelial Neoplasm by Histology Adenocarcinoma Urologic Neoplasms Urogenital Neoplasms Neoplasms by Site Kidney Diseases Urologic Diseases
Interventions
DRUG OTHER
No Results Yet
NCT05916313 | ACTIVE_NOT_RECRUITING | PHASE1
18 Participants

A Study to Test How Well Different Doses of BI 764532 Are Tolerated by People With a Tumour in the Brain That is Positive for DLL3

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-01-30
Completion: 2026-02-23
Conditions
Glioma
Interventions
DRUG
No Results Yet
NCT05906095 | ENROLLING_BY_INVITATION | NA
10160 Participants

Pragmatic Trial to Increase Quality of Care in State Veterans Homes

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2024-01-08
Completion: 2026-07-31
Conditions
Long-Term Care Accidental Falls
Interventions
BEHAVIORAL
No Results Yet
NCT05896267 | COMPLETED | NA
64 Participants

SpO2 Data Collection in Pediatric Patients Using INVSENSOR00061

Study Type: INTERVENTIONAL
Last Updated: 2025-11-12
Start Date: 2023-05-15
Completion: 2023-06-22
Conditions
Spo2
Interventions
DEVICE
Results Available
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