Clinical Trials
Showing trials with last updates posted in 2025.
1584
Participants
A Trial to Learn How Well Finerenone Works and How Safe it is in Adult Participants With Non-diabetic Chronic Kidney Disease
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-09-21
Completion:
2026-01-05
Conditions
Non-diabetic Chronic Kidney Disease
Interventions
DRUG
No Results Yet
8
Participants
Decitabine/Cedazuridine and Enzalutamide for the Treatment of Metastatic Castrate Resistant Prostate Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-01-26
Completion:
2024-12-17
Conditions
Castration-Resistant Prostate Carcinoma
Stage IV Prostate Cancer AJCC v8
Stage IVA Prostate Cancer AJCC v8
Stage IVB Prostate Cancer AJCC v8
Interventions
DRUG
No Results Yet
21
Participants
Prophylaxis Regimen for Hemophilia A Patients
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-07-28
Completion:
2024-09-12
Conditions
Hemophilia A
Prophylaxis of Bleeding
Interventions
BIOLOGICAL
100
Participants
Affixus Natural Nail System Humeral Nail PMCF
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2022-08-29
Completion:
2027-08-31
Conditions
Humeral Fractures, Proximal
Humeral Fractures
Interventions
DEVICE
No Results Yet
200
Participants
BONAPH1DE, A Prospective Observational Study of Patients With Primary Hyperoxaluria Type 1 (PH1)
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2021-12-13
Completion:
2028-09-01
Conditions
Primary Hyperoxaluria Type 1
No Results Yet
246
Participants
A Phase 1b/2 Study of Sonrotoclax (BGB-11417) as Monotherapy and in Various Combinations With Dexamethasone Plus Carfilzomib, Dexamethasone Plus Daratumumab, and Dexamethasone Plus Pomalidomide in Multiple Myeloma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-09-16
Completion:
2026-11-30
Conditions
Relapsed/Refractory Multiple Myeloma
Interventions
DRUG
No Results Yet
160
Participants
A Study to Test BI 765179 Alone and in Combination With Ezabenlimab in Patients With Advanced Cancer (Solid Tumors) and BI 765179 in Combination With Pembrolizumab in Patients With Advanced Head and Neck Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-10-18
Completion:
2026-07-28
Conditions
Neoplasms
Interventions
DRUG
No Results Yet
60
Participants
Bolster: Caregiver App to Reduce Duration of Untreated Psychosis
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-08-11
Completion:
2024-10-04
Conditions
Caregiver to a Young Adult With Early Psychosis
Interventions
BEHAVIORAL
110
Participants
Safety and Efficacy Study of Investigational Agents as Monotherapy or in Combination With Pembrolizumab (MK-3475) for the Treatment of Extensive-Stage Small Cell Lung Cancer (ES-SCLC) in Need of Second-Line Therapy (MK-3475-B98/KEYNOTE-B98)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-08-19
Completion:
2026-05-20
Conditions
Small Cell Lung Carcinoma
Interventions
BIOLOGICAL
DRUG
No Results Yet
56
Participants
tDCS and Cognitive Training in Active Duty Service Members With Mild TBI: A Pilot Study
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-01-19
Completion:
2025-06-30
Conditions
Brain Concussion
Brain Trauma
Attention Concentration Difficulty
Brain Injuries
Brain Injuries, Traumatic
Neurocognitive Dysfunction
Attention Impaired
Memory Impairment
Mild Traumatic Brain Injury
Mild Cognitive Impairment
Interventions
COMBINATION_PRODUCT
No Results Yet
85
Participants
Medical-legal Partnerships to Prevent Evictions and Homelessness Among Veterans
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2022-02-01
Completion:
2026-03-01
Conditions
Homelessness
Mental Health
Interventions
BEHAVIORAL
No Results Yet
1100
Participants
A Multi-Center Natural History of Urothelial Cancer and Rare Genitourinary Tract Malignancies
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2022-10-24
Completion:
2041-12-01
Conditions
Urothelial Cancer
Bladder Cancer
Genitourinary Cancer
Urogenital Neoplasms
Urogenital Cancer
No Results Yet
240
Participants
Reduction of Allogenic Blood Transfusion in Locally Advanced Kidney Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-07-23
Completion:
2025-02-12
Conditions
Kidney Cancer
Interventions
PROCEDURE
No Results Yet
820
Participants
Outpatient Treatment With Anti-Coronavirus Immunoglobulin
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-08-06
Completion:
2026-08-01
Conditions
COVID
SARS-CoV2 Infection
Covid19
Interventions
BIOLOGICAL
OTHER
No Results Yet
200
Participants
A Study to Assess the Safety, Tolerability, and Pharmacokinetics of ABSK-011 in Patients With Advanced Solid Tumor
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2020-02-26
Completion:
2027-12-31
Conditions
Advanced Liver Cancer
Interventions
DRUG
No Results Yet
12
Participants
Registry to Collect Health Information Related to Fibrolamellar Cancer
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2021-11-24
Completion:
2025-11-10
Conditions
Fibrolamellar Cancer
FLC
Liver Cancer
Interventions
BEHAVIORAL
No Results Yet
260
Participants
Study of OCTAPLEX in Patients With Acute Major Bleeding on DOAC Therapy With Factor Xa Inhibitor
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-09-01
Completion:
2026-12-31
Conditions
Acute Major Bleeding
Interventions
DRUG
No Results Yet
112
Participants
Mitochondrial-targeted Antioxidant Supplementation for Improving Age-related Vascular Dysfunction in Humans
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-04-02
Completion:
2025-12-31
Conditions
Aging
Interventions
DIETARY_SUPPLEMENT
No Results Yet
1
Participants
Clinical Study of BDB018: Monotherapy and in Combination With Pembrolizumab in Subjects With Advanced Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-06-22
Completion:
2024-03-31
Conditions
Tumor, Solid
Interventions
DRUG
No Results Yet
1
Participants
BDB001-201: A Clinical Study of BDB001 in Patients With PD-(L)1 Refractory Solid Tumors
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-08-30
Completion:
2023-04-01
Conditions
Tumor, Solid
Interventions
DRUG
No Results Yet
21
Participants
Pilot Study to Investigate Magnetic Resonance (MR) Image Guided Focal Therapy in Prostate Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2023-11-20
Completion:
2027-05-01
Conditions
Prostate Cancer
Interventions
DEVICE
No Results Yet
625
Participants
Phase 2 Study Of VLA15, A Vaccine Candidate Against Lyme Borreliosis, In A Healthy Pediatric And Adult Study Population
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-03-08
Completion:
2022-03-25
Conditions
Lyme Borreliosis
Interventions
BIOLOGICAL
106
Participants
Role of GABAergic Transmission in Auditory Processing in Autism Spectrum Disorder
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-06-15
Completion:
2027-06-30
Conditions
Autism Spectrum Disorder
Interventions
DEVICE
No Results Yet
180
Participants
Study of IDE397 in Participants With Solid Tumors Harboring MTAP Deletion
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-04-14
Completion:
2026-12-31
Conditions
Solid Tumor
Interventions
DRUG
No Results Yet
100
Participants
Experimental Manipulation of Sleep and Circadian Rhythms and the Role Played on Reward Function in Teens
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-05-01
Completion:
2026-03-31
Conditions
Delayed Sleep Phase Syndrome
Interventions
OTHER
BEHAVIORAL
No Results Yet
1157
Participants
Trastuzumab Deruxtecan (T-DXd) With or Without Pertuzumab Versus Taxane, Trastuzumab and Pertuzumab in HER2-positive Metastatic Breast Cancer (DESTINY-Breast09)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-04-26
Completion:
2026-07-06
Conditions
Breast Cancer; HER2-positive; Metastatic
Interventions
DRUG
No Results Yet
26
Participants
Safety, Tolerability, and Pharmacokinetics of Lumateperone in Pediatric Patients With Schizophrenia or Schizoaffective Disorder
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-03-12
Completion:
2022-07-30
Conditions
Schizophrenia
Pediatric
Interventions
DRUG
380
Participants
A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-04-28
Completion:
2027-03-31
Conditions
Depression
Bipolar I Disorder
Interventions
DRUG
No Results Yet
260
Participants
A Study of BGB-11417 in Participants With Myeloid Malignancies
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-05-24
Completion:
2028-02-08
Conditions
Acute Myeloid Leukemia
Myelodysplastic Syndromes
Myelodysplastic/Myeloproliferative Neoplasm
Interventions
DRUG
No Results Yet
350
Participants
LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naรฏve
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-04-22
Completion:
2026-06-30
Conditions
Superficial Bladder Cancer
Non-muscle Invasive Bladder Cancer With Carcinoma in Situ
Interventions
DRUG
No Results Yet
600
Participants
Long-term Safety Study of Rimegepant in Pediatric Subjects for the Acute Treatment of Migraine
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-04-28
Completion:
2030-07-31
Conditions
Acute Treatment of Migraine
Interventions
DRUG
No Results Yet
188
Participants
Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-04-27
Completion:
2029-06-30
Conditions
Recurrent Head and Neck Squamous Cell Carcinoma
Recurrent Hypopharyngeal Squamous Cell Carcinoma
Recurrent Laryngeal Squamous Cell Carcinoma
Recurrent Oral Cavity Squamous Cell Carcinoma
Recurrent Oropharyngeal Squamous Cell Carcinoma
Interventions
DRUG
PROCEDURE
RADIATION
BIOLOGICAL
No Results Yet
40
Participants
Longitudinal Assessment of Marrow and Blood in Patients With Glioblastoma
Study Type:
OBSERVATIONAL
Last Updated:
2025-11-12
Start Date:
2024-02-05
Completion:
2027-11-01
Conditions
Glioblastoma
Interventions
OTHER
No Results Yet
2100
Participants
Randomized Study in Children and Adolescents With Migraine: Acute Treatment
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-01-15
Completion:
2029-01-09
Conditions
Pediatric Migraine
Interventions
DRUG
No Results Yet
87
Participants
A Study of LY3484356 in Women With Breast Cancer Before Having Surgery
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-04-21
Completion:
2022-11-11
Conditions
Breast Cancer
Interventions
DRUG
249
Participants
Testing the Addition of MEDI4736 (Durvalumab) to Chemotherapy Before Surgery for Patients With High-Grade Upper Urinary Tract Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-11-12
Completion:
2027-09-30
Conditions
Renal Pelvis and Ureter Urothelial Carcinoma
Interventions
PROCEDURE
DRUG
BIOLOGICAL
No Results Yet
484
Participants
A Phase 3 Trial of Epcoritamab vs Investigator's Choice Chemotherapy in Relapsed/Refractory (R/R) Diffuse Large B-cell Lymphoma (DLBCL)
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-01-13
Completion:
2025-10-13
Conditions
Diffuse Large B-cell Lymphoma
Interventions
BIOLOGICAL
DRUG
No Results Yet
45
Participants
A Pilot Study to Assess Safety and Efficacy of SIR1-365 in Patients With Severe COVID-19
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2020-12-18
Completion:
2021-11-27
Conditions
Corona Virus Infection
Interventions
DRUG
170
Participants
Autologous LN-145 in Patients With Metastatic Non-Small-Cell Lung Cancer
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2021-05-07
Completion:
2030-12-31
Conditions
Metastatic Non Small Cell Lung Cancer
Interventions
BIOLOGICAL
No Results Yet
806
Participants
Phase 2 Trial of Adagrasib Monotherapy and in Combination With Pembrolizumab and a Phase 3 Trial of Adagrasib in Combination in Patients With a KRAS G12C Mutation KRYSTAL-7
Study Type:
INTERVENTIONAL
Last Updated:
2025-11-12
Start Date:
2020-12-02
Completion:
2028-10-31
Conditions
Advanced Non-Small Cell Lung Cancer
Metastatic Non-Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
Showing 40 trials per page ยท Total 107903 trials