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Clinical Trials

Showing trials with last updates posted in 2024.

NCT05480865 | TERMINATED | PHASE1
28 Participants

SHP2 Inhibitor BBP-398 in Combination With Sotorasib in Patients With Advanced Solid Tumors and a KRAS-G12C Mutation

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2022-07-06
Completion: 2024-08-22
Conditions
Solid Tumor, Adult Metastatic Solid Tumor Metastatic NSCLC Non Small Cell Lung Cancer
Interventions
DRUG
No Results Yet
NCT05467670 | RECRUITING | PHASE2
31 Participants

Safety and Efficacy of Anti-CD47, ALX148 in Combination with Liposomal Doxorubicin and Pembrolizumab in Recurrent Platinum-resistant Ovarian Cancer

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2023-03-30
Completion: 2029-09-30
Conditions
Ovarian Cancer
Interventions
DRUG
No Results Yet
NCT05454254 | COMPLETED | NA
20 Participants

Effect of Muscle Strengthening Training in Adults with Fontan Circulation

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2022-08-15
Completion: 2023-11-30
Conditions
Congenital Heart Disease Univentricular Heart
Interventions
OTHER
No Results Yet
NCT05451251 | RECRUITING | PHASE1
6 Participants

Deep Brain Stimulation for Refractory Trigeminal Neuralgia with a Pontine Lesion

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2024-10-15
Completion: 2025-10-15
Conditions
Trigeminal Neuralgia
Interventions
DEVICE
No Results Yet
NCT05450185 | RECRUITING
600 Participants

Filter Lifespan in Continuous Renal Replacement Therapy

Study Type: OBSERVATIONAL
Last Updated: 2024-12-12
Start Date: 2023-03-02
Completion: 2025-05-31
Conditions
Critically Ill Continuous Renal Replacement Therapy Infections
Interventions
PROCEDURE
No Results Yet
NCT05400434 | RECRUITING | NA
300 Participants

Natural Helpers and PCIT

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2018-12-03
Completion: 2025-12-27
Conditions
Child Behavior Parenting
Interventions
BEHAVIORAL
No Results Yet
NCT05375084 | TERMINATED | PHASE1
21 Participants

SHP2 Inhibitor BBP-398 in Combination With Nivolumab in Patients With Advanced Non-Small Cell Lung Cancer With a KRAS Mutation

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2022-10-20
Completion: 2024-04-12
Conditions
Non Small Cell Lung Cancer Solid Tumor
Interventions
DRUG
No Results Yet
NCT05366218 | RECRUITING | PHASE1/PHASE2
20 Participants

Tafasitamab (MOR00208) in Pediatric Patients with Relapsed or Refractory Acute B Lineage Leukemia

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2023-03-08
Completion: 2027-03-31
Conditions
ALL, Childhood B-Cell Acute Lymphoid Leukemia Relapse Acute Lymphocytic Leukemia Refractory
Interventions
BIOLOGICAL
No Results Yet
NCT05356806 | RECRUITING
277 Participants

Incidence of Peri-implant Mucositis in Patients With Treated Periodontitis

Study Type: OBSERVATIONAL
Last Updated: 2024-12-12
Start Date: 2022-01-10
Completion: 2025-12-31
Conditions
Peri-implant Mucositis
Interventions
OTHER
No Results Yet
NCT05345769 | COMPLETED | PHASE1
21 Participants

Safety and Efficacy of AM712 in Patients with NAMD

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2022-04-28
Completion: 2024-11-04
Conditions
Neovascular Age-related Macular Degeneration
Interventions
BIOLOGICAL
No Results Yet
NCT05339529 | RECRUITING | NA
330 Participants

Protective Effect of Thymosin Α1 Against Negative Immune Dysregulation and Organ Dysfunction After Acute Aortic Dissection Surgery (PANDA II)

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2022-07-01
Completion: 2025-12-31
Conditions
Acute Aortic Syndrome Aortic Dissection Type a
Interventions
DRUG
No Results Yet
NCT05335317 | RECRUITING | NA
120 Participants

Treatment of Vaginal Atrophy With Low Intensity Nanosecond Neodymium Laser

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2022-04-18
Completion: 2025-09-01
Conditions
Postmenopausal Period Vaginal Atrophy Vaginal Prolapse
Interventions
DEVICE DRUG DIAGNOSTIC_TEST OTHER
No Results Yet
NCT05324280 | RECRUITING | NA
68 Participants

Acupuncture in a Multidisciplinary Approach for Vulvodynia and Chronic Pelvic Pain

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2022-06-23
Completion: 2026-01-31
Conditions
Vulvodynia Chronic Pelvic Pain
Interventions
PROCEDURE
No Results Yet
NCT05320068 | COMPLETED | PHASE3
24 Participants

Oral Vancomycin Vs Placebo in the Prevention of Recurrence of Clostridioides Difficile's Infection

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2022-08-02
Completion: 2024-03-01
Conditions
Clostridioides Difficile Infection
Interventions
DRUG
No Results Yet
NCT05315154 | RECRUITING | NA
800 Participants

Sentinel Lymph Node Biopsy Versus No Axillary Surgery in Early Breast Cancer

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2019-10-02
Completion: 2025-12-31
Conditions
Breast Cancer
Interventions
PROCEDURE
No Results Yet
NCT05278494 | RECRUITING | NA
160 Participants

Dextromethorphan for Treatment of Postoperative Pain

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2022-09-15
Completion: 2025-12-31
Conditions
Post-operative Pain
Interventions
DRUG
No Results Yet
NCT05276622 | TERMINATED
64 Participants

Patient and Care Partner Experiences Living With Multiple Myeloma (PaCE-MM)

Study Type: OBSERVATIONAL
Last Updated: 2024-12-12
Start Date: 2022-02-08
Completion: 2023-10-03
Conditions
Multiple Myeloma
Interventions
OTHER
No Results Yet
NCT05269589 | RECRUITING | NA
44 Participants

Home-based Heat Therapy for Type 2 Diabetes

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2022-02-18
Completion: 2026-12-31
Conditions
Diabetes Mellitus, Type 2 Heat Exposure
Interventions
OTHER
No Results Yet
NCT05207722 | TERMINATED | PHASE1/PHASE2
1 Participants

CYNK-101 in Combination with Trastuzumab and Pembrolizumab in Patients with Locally Advanced Unresectable or Metastatic HER2-Positive Gastric or Gastroesophageal Junction (G/GEJ) Adenocarcinoma

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2022-04-14
Completion: 2024-02-15
Conditions
Metastatic HER2 Positive Gastroesophageal Junction Cancer
Interventions
BIOLOGICAL DRUG
No Results Yet
NCT05161078 | ENROLLING_BY_INVITATION
1000 Participants

Improving Continuous Renal Replacement Therapy Outcomes in Neonates and Infants Through Interdisciplinary Collaboration

Study Type: OBSERVATIONAL
Last Updated: 2024-12-12
Start Date: 2021-12-16
Completion: 2027-12-31
Conditions
Acute Kidney Injury Chronic Kidney Diseases Renal Dialysis
Interventions
DEVICE
No Results Yet
NCT05159349 | RECRUITING
1200 Participants

Mental Health During the Whole Life Cycle of Community Patients with Schizophrenia

Study Type: OBSERVATIONAL
Last Updated: 2024-12-12
Start Date: 2021-12-01
Completion: 2025-12-31
Conditions
Schizophrenia
No Results Yet
NCT05122533 | COMPLETED
100 Participants

Reliability of Clinical Limb-length Measurements Methods

Study Type: OBSERVATIONAL
Last Updated: 2024-12-12
Start Date: 2021-10-01
Completion: 2022-06-30
Conditions
Leg Length Inequality
Interventions
DIAGNOSTIC_TEST
No Results Yet
NCT05114057 | NOT_YET_RECRUITING | NA
1380 Participants

Use of NGAL for Fluid Dosing and CRRT Initiation in Pediatric and Neonatal AKI

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2025-12-01
Completion: 2028-08-31
Conditions
Acute Kidney Injury Acute Kidney Injury Due to Sepsis Neonatal Sepsis
Interventions
OTHER
No Results Yet
NCT05094544 | WITHDRAWN | NA
0 Participants

Pre-Operative Immuno-Modulatory SBRT (POIMS Trial): A Pilot Trial in Early Stage NSCLC

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2021-10-01
Completion: 2023-03-23
Conditions
Non-small Cell Lung Cancer
Interventions
RADIATION
No Results Yet
NCT05086341 | COMPLETED | NA
22 Participants

A Pilot- and Feasibility Trial of the EHealth Tool My COPD for People with COPD

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2021-11-05
Completion: 2023-10-01
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
DEVICE
No Results Yet
NCT05070468 | COMPLETED | PHASE3
84 Participants

Effect of Dexamethasone on Labor Induction

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2020-11-22
Completion: 2021-01-21
Conditions
Dexamethasone Pregnancy
Interventions
DRUG
Results Available
NCT05055934 | COMPLETED | PHASE2
112 Participants

Study of the Effectiveness and Safety of SHR-1314 for Psoriatic Arthritis

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2021-10-22
Completion: 2024-06-05
Conditions
Psoriatic Arthritis
Interventions
DRUG
No Results Yet
NCT05036044 | COMPLETED
1002 Participants

Stroke and Carotid-Cerebral Vascular Disease After CABG

Study Type: OBSERVATIONAL
Last Updated: 2024-12-12
Start Date: 2021-09-04
Completion: 2023-01-21
Conditions
Coronary Artery Bypass
No Results Yet
NCT05020899 | COMPLETED | NA
109 Participants

Quit For Life (QFL): Smoking Cessation Among Chinese Smokers Living With HIV

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2022-02-24
Completion: 2023-08-01
Conditions
Smoking Cessation HIV Infections
Interventions
BEHAVIORAL OTHER
Results Available
NCT05015543 | COMPLETED | NA
54 Participants

Physical Training in Glioblastoma Patients During Cytotoxic Therapy

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2020-07-23
Completion: 2024-10-17
Conditions
Glioblastoma
Interventions
OTHER
No Results Yet
NCT05000957 | ACTIVE_NOT_RECRUITING | NA
129 Participants

Pelvic Organs Prolapse Treatment Using Neodymium Laser

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2021-10-03
Completion: 2025-04-01
Conditions
Pelvic Organ Prolapse Female Urogenital Diseases
Interventions
DEVICE DIAGNOSTIC_TEST PROCEDURE OTHER GENETIC
No Results Yet
NCT04996758 | COMPLETED | PHASE2
40 Participants

Toripalimab and Anlotinib Combination Treatment in Patients With Recurrent or Metastatic Nasopharyngeal Carcinoma After Failure of at Least One Line of Platinum-Based Chemotherapy (TORAL)

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2021-10-30
Completion: 2023-09-30
Conditions
Nasopharyngeal Carcinoma Recurrent or Metastatic Nasopharyngeal Carcinoma
Interventions
DRUG
No Results Yet
NCT04977362 | COMPLETED | NA
201 Participants

Interdisciplinary Perioperative Care in Minimally-invasive Heart Valve Surgery

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2021-07-01
Completion: 2024-03-24
Conditions
Heart Valve Diseases
Interventions
OTHER
No Results Yet
NCT04958109 | COMPLETED | PHASE1
16 Participants

Evaluation of Kisspeptin Glucose-Stimulated Insulin Secretion With Oral Glucose Tolerance Test

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2021-10-28
Completion: 2022-10-31
Conditions
Metabolic Diseases
Interventions
DIAGNOSTIC_TEST DRUG
Results Available
NCT04946019 | COMPLETED | PHASE2
55 Participants

MR-Linac Guided Adaptive FSRT for Brain Metastases From Non-small Cell Lung Cancer

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2021-06-01
Completion: 2024-07-17
Conditions
Non-small Cell Lung Cancer
Interventions
COMBINATION_PRODUCT
No Results Yet
NCT04935086 | COMPLETED
370 Participants

Risk Factors for Predictors of MACEs After RA-CABG

Study Type: OBSERVATIONAL
Last Updated: 2024-12-12
Start Date: 2021-06-30
Completion: 2021-11-30
Conditions
Coronary Artery Disease
No Results Yet
NCT04914611 | RECRUITING
10000 Participants

Real World Assessment of People Living With Chronic Hepatitis B in Australia

Study Type: OBSERVATIONAL
Last Updated: 2024-12-12
Start Date: 2022-02-17
Completion: 2026-07-01
Conditions
Hepatitis B
Interventions
OTHER
No Results Yet
NCT04891419 | COMPLETED | PHASE3
168 Participants

JUVÉDERM® VOLUMA® With Lidocaine for Correction of Temple Hollowing in Chinese Population

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2021-07-20
Completion: 2023-11-22
Conditions
Temple Hollowing
Interventions
DEVICE
Results Available
NCT04859504 | COMPLETED | NA
60 Participants

Developing Dual-channel Transcranial Alternating Current Stimulations Targeting Negative Symptoms in Schizophrenia

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2021-04-01
Completion: 2024-07-31
Conditions
Schizophrenia Transcranial Alternating Current Stimulations Negative Symptoms
Interventions
DEVICE
No Results Yet
NCT04856722 | COMPLETED | NA
255 Participants

Mini-PNL, RIRS, and ESWL for Treatment of Medium-Sized, High-Density, Non-Lower Pole, Renal Stones

Study Type: INTERVENTIONAL
Last Updated: 2024-12-12
Start Date: 2021-04-05
Completion: 2024-06-04
Conditions
Renal Stone Percutaneous Nephrolithotomy Retrograde Intrarenal Surgery Extracorporeal Shockwave Lithotripsy
Interventions
PROCEDURE
No Results Yet
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