Stroke and Carotid-Cerebral Vascular Disease After CABG

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

1002 participants

Study Classification

OBSERVATIONAL

Study Start Date

2021-09-04

Study Completion Date

2023-05-31

Brief Summary

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Review the data of patients who underwent coronary artery bypass grafting (CABG) at the Department of Cardiovascular Surgery in Ruijin hospital from March 2020 to May 2022, including medical history, head and neck CTA, head CT scan, and early postoperative (within 7 days after surgery) neurological complications (defined as a composite of stroke, delayed awakening and severe delirium) . Case-control and retrospective cohorts were built to explore risk factors of early postoperative neurological complications, And its association with baseline carotid-cerebral vascular disease.

Describe the epidemiological data of early postoperative neurological complications (stroke, delayed awakening, and severe delirium) after CABG surgery (within 7 days after surgery); explore independent risk factors of compound neurological complications, build predictive models; compare the effects of carotid-cerebral artery disease on early postoperative compound neurological complications.

Detailed Description

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Conditions

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Coronary Artery Bypass

Keywords

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Neurological complications Carotid-cerebral artery disease CABG CAD

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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With moderate or severe carotid-cerebral artery disease

moderate (stenosis 50-69%) or severe (stenosis 70-100%) carotid-cerebral artery disease

No interventions assigned to this group

Without moderate or severe carotid-cerebral artery disease

mild (stenosis 30-49%) or no (stenosis 0-29%) carotid-cerebral artery disease

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

1. Patients who received CABG at the department of cardiac surgery in our hospital.
2. Surgery that patients received includes both isolated and combined CABG surgery.
3. Includes both cardiopulmonary and non-cardiopulmonary bypass.

Exclusion Criteria

1. Without complete preoperative examination data, such as carotid-cerebral artery CTA, head CT imaging results and so on.
2. Without complete baseline medical history and 7 day post-surgery record.

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Responsible Party

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Qiang Zhao,MD

Professor and Director, Department of Cardiovascular Surgery, Vice President, Ruijin Hospital

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Qiang Zhao, MD

Role: PRINCIPAL_INVESTIGATOR

Ruijin Hospital

Locations

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Ruijin Hospital Shanghai Jiao Tong University School of Medicine

Shanghai, Shanghai Municipality, China

Site Status

Countries

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China

Other Identifiers

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KY-2021127

Identifier Type: -

Identifier Source: org_study_id