A Block Method for Pain After Back Surgery

NCT ID: NCT07346599

Last Updated: 2026-01-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

102 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-09-27

Study Completion Date

2022-05-20

Brief Summary

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The purpose of this clinical trial is to evaluate whether bilateral lumbar erector spinae plane (ESP) block can reduce postoperative pain in adult patients undergoing lumbar spine surgery. The study also assesses the safety of this method and its effects on the recovery process. The main questions it aims to answer are:

Do patients who receive the ESP block experience less postoperative pain? Do these patients require fewer opioid (morphine-derived) analgesics? Does the first analgesic requirement occur later? Do patients mobilize earlier (stand/walk sooner)? Does the ESP block affect hemodynamic stability during and after surgery? Researchers will compare the ESP block group with the standard analgesia group to determine whether these effects occur.

Participants:

Patients in this study will be asked to:

Be randomly assigned to one of two groups before lumbar spine surgery Receive either a bilateral ESP block or standard analgesic therapy

Undergo postoperative follow-up including:

measurement of pain scores, recording of analgesic consumption, assessment of time to first analgesic requirement, monitoring of mobilization time, valuation of possible side effects

Detailed Description

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This randomized controlled study was designed to evaluate the effect of bilateral lumbar erector spinae plane (ESP) block on postoperative analgesia in patients undergoing lumbar spine surgery. A total of 102 patients scheduled for lumbar spine surgery were enrolled in the study and randomly assigned into two groups. One group received a bilateral ESP block at the L2-L4 levels using 20 mL of 0.25% bupivacaine on each side, while the control group received standard postoperative analgesia.

Postoperative pain assessment, opioid consumption, time to first analgesic request, mobilization time, intraoperative hemodynamic parameters, and the occurrence of adverse events were prospectively recorded according to a predefined follow-up protocol. The study was conducted using a prospective, randomized design to assess the efficacy and safety of bilateral lumbar ESP block for postoperative pain management in lumbar spine surgery.

Conditions

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Nerve Block Postoperative Pain Randomised Clinical Trial

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Participants

Study Groups

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ESP BLOCK,

Group Type ACTIVE_COMPARATOR

ESP block group

Intervention Type PROCEDURE

BILATERAL TWO-LEVEL ESP BLOCK WAS APPLIED TO PATIENTS UNDERGOING LUMBAR SPINAL SURGERY.

CONTROL GROUP

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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ESP block group

BILATERAL TWO-LEVEL ESP BLOCK WAS APPLIED TO PATIENTS UNDERGOING LUMBAR SPINAL SURGERY.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Patients aged 18 and over, 80 and under
* American Society of Anesthesiologists Patient Classification Score (ASA) between I and Ⅲ
* Patients who can cooperate and give consent
* No chronic analgesic or opioid use
* No mental or psychiatric disorders
* No alcohol or illicit drug use
* Patients scheduled for elective spinal surgery

Exclusion Criteria

* -Patients who withdrew from participation at any time during the study
* Foreign nationals who could not be contacted
* Patients under 18 and over 80
* Patients with an ASA score of Ⅳ or higher
* Patients scheduled for emergency surgery
* Pregnant women and breastfeeding mothers
* Bleeding diathesis
* Drug allergy
* Anticoagulant use
* Local/systemic infection
* Serious arrhythmia
Minimum Eligible Age

18 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Kutahya City Hospital

OTHER

Sponsor Role lead

Responsible Party

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MERVE KAYNAK

specialist doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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merve kaynak

Role: PRINCIPAL_INVESTIGATOR

Kütahya City Hospital

Ali Kaynak

Role: STUDY_CHAIR

Kütahya City Hospital

bilal a bezen

Role: STUDY_CHAIR

Afyonkarahisar Health Sciences University Hospital

remziye sıvacı

Role: STUDY_DIRECTOR

Afyonkarahisar Health Sciences University Hospital

elif d bakı

Role: STUDY_CHAIR

Afyonkarahisar Health Sciences University Hospital

serhat yıldızhan

Role: STUDY_CHAIR

Afyonkarahisar Health Sciences University Hospital

Locations

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Afyonkarahisar Health Sciences University Hospital

Afyonkarahisar, Merkez, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

References

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Forero M, Adhikary SD, Lopez H, Tsui C, Chin KJ. The Erector Spinae Plane Block: A Novel Analgesic Technique in Thoracic Neuropathic Pain. Reg Anesth Pain Med. 2016 Sep-Oct;41(5):621-7. doi: 10.1097/AAP.0000000000000451.

Reference Type BACKGROUND
PMID: 27501016 (View on PubMed)

Goel VK, Chandramohan M, Murugan C, Shetty AP, Subramanian B, Kanna RM, Rajasekaran S. Clinical efficacy of ultrasound guided bilateral erector spinae block for single-level lumbar fusion surgery: a prospective, randomized, case-control study. Spine J. 2021 Nov;21(11):1873-1880. doi: 10.1016/j.spinee.2021.06.015. Epub 2021 Jun 23.

Reference Type RESULT
PMID: 34171466 (View on PubMed)

Tseng V, Xu JL. Erector Spinae Plane Block for Postoperative Analgesia in Lumbar Spine Surgery: Is There a Better Option? J Neurosurg Anesthesiol. 2021 Jan;33(1):92. doi: 10.1097/ANA.0000000000000631. No abstract available.

Reference Type RESULT
PMID: 31343504 (View on PubMed)

Liu H, Zhu J, Wen J, Fu Q. Ultrasound-guided erector spinae plane block for postoperative short-term outcomes in lumbar spine surgery: A meta-analysis and systematic review. Medicine (Baltimore). 2023 Feb 17;102(7):e32981. doi: 10.1097/MD.0000000000032981.

Reference Type RESULT
PMID: 36800574 (View on PubMed)

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Document Type: Informed Consent Form

View Document

Other Identifiers

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448

Identifier Type: -

Identifier Source: org_study_id

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