Effects of Erector Spinae Plane Block and Intrathecal Morphine Administration on Intraoperative Sevoflurane Consumption

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

99 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-11-20

Study Completion Date

2025-01-15

Brief Summary

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In our study, the investigators aimed to compare the intraoperative sevoflurane consumption and postoperative analgesic needs of patients who underwent lumbar disc herniation surgery and received either ESP block or ITM in the preoperative period with a control group.

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Detailed Description

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The amount of volatile anesthetic agents used for anesthesia maintenance can be significantly reduced with potent and long-acting analgesic interventions administered during the preoperative period. Such interventions enable the maintenance of anesthesia with more optimal levels of agents during surgery, providing significant advantages in terms of both patient safety and cost.

Studies have recommended multimodal analgesia approaches involving the Erector Spinae Plane (ESP) block and intrathecal morphine (ITM) injection for various surgical procedures. These two methods, through different mechanisms of action, not only reduce intraoperative anesthetic agent consumption but also play a critical role in postoperative pain management. Although studies have investigated the effects of ESP block and ITM injection on intraoperative volatile anesthetic consumption, there is limited research directly comparing their impacts on volatile anesthetic consumption and postoperative analgesic requirements.

In our study, we aimed to compare the intraoperative sevoflurane consumption and postoperative analgesic needs of patients who underwent lumbar disc herniation surgery and received either ESP block or ITM in the preoperative period with a control group.

Conditions

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Postoperative Pain Anesthesia

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

PROSPECTIVE

Study Groups

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ESP

ESP block was applied to patients in this group in the preoperative period.

ESP block

Intervention Type OTHER

ESP block was applied to the patients.

ITM

Intrathecal morphine was applied to patients in this group in the preoperative period.

ITM

Intervention Type OTHER

ITM was applied to the patients.

Control

Patients who did not undergo ESP block or ITM were included in this group.

No interventions assigned to this group

Interventions

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ESP block

ESP block was applied to the patients.

Intervention Type OTHER

ITM

ITM was applied to the patients.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Patients aged over 18 years
* Patients receiving general anesthesia
* Patients with an ASA score of I-II
* Patients undergoing elective surgery for single-level lumbar disc herniation
* Patients who provided informed consent after being informed

Exclusion Criteria

Patients who did not provide informed consent after being informed

* Patients over 65 years of age
* Patients with an ASA score of III or higher
* Patients with recurrent lumbar disc herniation (LDH)
* Patients undergoing surgery for multi-level LDH
* Patients with a body mass index (BMI) of 30 or higher
* Patients with allergies to morphine or bupivacaine
* Patients with major cardiac, respiratory, hepatic, renal, neurological, or psychiatric diseases
* Patients with a history of alcohol or substance abuse
* Patients with a local infection at the injection site
* Patients with bleeding diathesis
* Patients with a history of anticoagulant medication use
* Patients with contraindications to spinal or regional anesthesia

Minimum Eligible Age

18 Years

Maximum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No