Erector Spinae Plane Block Versus Serratus Anterior Plane Block

NCT ID: NCT06862752

Last Updated: 2026-02-18

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 80 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2025-04-01
• Study Completion Date: 2026-01-15

Brief Summary

the aim of the study compare the analgesic effect of erector spinae block and serratus anterior block in breast surgery

Detailed Description

Breast reduction surgery is a common cosmetic surgical procedure. Providing effective analgesia has a crucial role in reducing side effects, catalyzing postoperative recovery, and increasing patient satisfaction. Regional anesthesia techniques are generally used for postoperative analgesia to decrease opioid-related side effects. Fascial plane block has gained popularity for breast analgesia. The investigator aimed to consider the effects of ESP block or Serratus Anterior Plane block on postoperative analgesia in breast reduction surgery.

Conditions

Post Operative Pain; Opioid-Related Disorders

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: TRIPLE

Study Groups

ESP block group

Bilateral ultrasound guided erector spine plane (ESP) block will be performe preoperatively at T5 level. 20 mL local anesthetics (10 mL 0.5% bupivacaine + 10 mL serum physiologic % l) will be injected deep to the erector spinae muscle

Group Type: ACTIVE_COMPARATOR

erector spine plane (ESP) block

Intervention Type: PROCEDURE

Bilateral ultrasound guided erector spine plane (ESP) block will be performe preoperatively at T5 level. 20 mL local anesthetics (10 mL 0.5% bupivacaine + 10 mL serum physiologic % l) will be injected deep to the erector spinae muscle.

SAP Block grup

Bilateral ultrasound guided serratus plane block with 20 ml %0,25 bupivacaine at the midaxillary 5. Rib

Group Type: OTHER

Serratus Anterior Plane Block

Intervention Type: PROCEDURE

Bilateral ultrasound guided serratus plane block with 20 ml %0,25 bupivacaine at the midaxillary 5. Rib

Interventions

erector spine plane (ESP) block

Bilateral ultrasound guided erector spine plane (ESP) block will be performe preoperatively at T5 level. 20 mL local anesthetics (10 mL 0.5% bupivacaine + 10 mL serum physiologic % l) will be injected deep to the erector spinae muscle.

Intervention Type: PROCEDURE

Serratus Anterior Plane Block

Bilateral ultrasound guided serratus plane block with 20 ml %0,25 bupivacaine at the midaxillary 5. Rib

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• American Society of Anesthesiologists (ASA) I-II,
• 18-65 years of age, adult,
• female patients
• undergoing elective breast reduction surgery

Exclusion Criteria

• Allergy to amide-type local anesthetics
• Infection at the block injection site
• Severe obesity (BMI > 35 kg/m2)
• Liver or renal deficiency
• Patients with anatomical deformities
• Recent use of analgesic drugs
• Patient refusal or inability to consent

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: No

Sponsors

Sisli Hamidiye Etfal Training and Research Hospital

OTHER

Sponsor Role: lead

Responsible Party

Leyla Kılınc

associate professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

AYSE SURHAN CINAR

Role: STUDY_CHAIR

SISLI HAMIDIYE ETFAL RESEARCH AND TRAINING

Locations

Sisli etfal research and training hospital

Istanbul, , Turkey (Türkiye)

Countries

Turkey (Türkiye)

Other Identifiers

leyla-25

Identifier Type: -

Identifier Source: org_study_id