CT-Angiography Versus Angiogram as Ancillary Tests in the Determination of Death by Neurologic Criteria

NCT ID: NCT07341490

Last Updated: 2026-01-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

50 participants

Study Classification

OBSERVATIONAL

Study Start Date

2026-01-31

Study Completion Date

2028-12-31

Brief Summary

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Diagnostic performance of a novel protocol for computed tomography-angiography, as ancillary test in the determination of complete cerebral infarction, in comparison to four vessel angiography.

Detailed Description

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Conditions

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Infarction, Brain

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

PROSPECTIVE

Study Groups

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Suspected Complete Cerebral Infarction

Patients with severe acute brain injury, in whom complete cerebral infarction has been declared by direct neurological criteria, but ancillary testing is warranted due to specific circumstances.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Adults 18 years or older
* Ongoing critical care due to severe acute brain injury
* Four vessel angiography necessary for the determination of complete cerebral infarction, according to Swedish legislation

Exclusion Criteria

* Treatment with extracorporeal membrane oxygenation (ECMO)
* Radiologic examination by computed tomography deemed too challenging due to respiratory or circulatory instability, as determined by responsible clinician
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Karolinska Institutet

OTHER

Sponsor Role collaborator

Region Stockholm

OTHER_GOV

Sponsor Role lead

Responsible Party

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Peter Rudberg

M.D. Ph.D.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Karolinska University Hospital

Stockholm, , Sweden

Site Status RECRUITING

Countries

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Sweden

Central Contacts

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Peter C Rudberg, M.D. Ph.D.

Role: CONTACT

+46-8-1237000 ext. 72341

Anja Rosén, M.D.

Role: CONTACT

+46-8-12370000 ext. 94856

Facility Contacts

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Peter C Rudberg, M.D. Ph.D.

Role: primary

+46-8-12370000 ext. 72341

Anja Rosén, M.D.

Role: backup

+46-8-12370000 ext. 94856

Provided Documents

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Document Type: Study Protocol

View Document

Other Identifiers

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2025-4056

Identifier Type: -

Identifier Source: org_study_id

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