Effectiveness of Low -Versus High -Volume High -Intensity Interval Training in Patients With Chronic Heart Failure

NCT ID: NCT07325942

Last Updated: 2026-01-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

45 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-12-10

Study Completion Date

2026-06-06

Brief Summary

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this study aims to investigate the effect of low vs high volume- high intensity interval training on functional capacity and quality of life in chronic heart failure patients

Detailed Description

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Conditions

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Chronic Heart Failure

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Low volume high intensity interval training

This group will receive the usual care (standard medical treatment) in addition to LV-HIIT on a treadmill for 8 weeks, 2 sessions per week.

Group Type EXPERIMENTAL

low-volume high intensity interval training

Intervention Type OTHER

Low-volume HIIT (LV-HIIT) is a particularly time-efficient subtype of interval training, which has gained increasing attention in recent years. As per the previous definition, these brief training protocols typically involve≤10 min of intense exercise within a session lasting≤30 min including warm-up, recovery phases between intervals, and cool-down

Standard medical treatment

Intervention Type DRUG

standard medical treatment for chronic heart failure as per international guidlines

high volume high intensity interval training

In this group, the patients will receive the usual care (standard treatment) in addition to HV-HIIT on a treadmill for 8 weeks, 2 sessions per week

Group Type EXPERIMENTAL

High volume high intensity interval training

Intervention Type OTHER

long (2-4 min) bouts of high (not maximum) intensity exercise interspersed with recovery periods which have wide varieties in the protocols according to the intensity, duration, and number of intervals performed

Standard medical treatment

Intervention Type DRUG

standard medical treatment for chronic heart failure as per international guidlines

control group

It includes 15 patients who will receive standard medical treatment only

Group Type OTHER

Standard medical treatment

Intervention Type DRUG

standard medical treatment for chronic heart failure as per international guidlines

Interventions

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low-volume high intensity interval training

Low-volume HIIT (LV-HIIT) is a particularly time-efficient subtype of interval training, which has gained increasing attention in recent years. As per the previous definition, these brief training protocols typically involve≤10 min of intense exercise within a session lasting≤30 min including warm-up, recovery phases between intervals, and cool-down

Intervention Type OTHER

High volume high intensity interval training

long (2-4 min) bouts of high (not maximum) intensity exercise interspersed with recovery periods which have wide varieties in the protocols according to the intensity, duration, and number of intervals performed

Intervention Type OTHER

Standard medical treatment

standard medical treatment for chronic heart failure as per international guidlines

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

1. Chronic stable heart failure patient with reduced ejection fraction (EF \<40)
2. Age Above 18 years old
3. Both males and females
4. The ability to provide informed consent

Exclusion Criteria

1. Based on the Scientific Statement from the American Heart Association: contraindications for exercise Testing and Training. (Fletcher et al., 2013)

1. Acute myocardial infarction (MI), within 2 days
2. Ongoing unstable angina
3. Uncontrolled cardiac tachy or brady arrhythmia with hemodynamic compromise
4. Active endocarditis
5. Symptomatic severe aortic stenosis
6. Decompensated heart failure
7. Acute pulmonary embolism, pulmonary infarction, or deep vein thrombosis
8. Acute myocarditis or pericarditis
9. Acute aortic dissection
10. Physical disability that precludes safe and adequate testing or training
11. Known obstructive left main coronary artery stenosis
12. Hypertrophic obstructive cardiomyopathy with severe resting gradient
13. Recent stroke or transient ischemic attack
14. Mental impairment with limited ability to cooperate
15. Resting hypertension with systolic or diastolic blood pressures \>200/110 mmHg
16. Uncorrected medical conditions, such as significant anemia, important electrolyte imbalance, and hyperthyroidism
2. Acute decompensated heart failure NYHA class IV
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Aya Ibrahim Elshenawy Elshenawy

physical therapy specialist

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Cairo University

Cairo, Giza Governorate, Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Aya I Elshenawy

Role: CONTACT

+01098811085

Facility Contacts

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Aya I Elshenawy

Role: primary

+201098811085

Other Identifiers

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P.T.REC/012/005825

Identifier Type: -

Identifier Source: org_study_id

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