Comparative Analysis of SUV Measurements Using Different Correction Methods in Oncological PET/CT Imaging.

NCT ID: NCT07306975

Last Updated: 2025-12-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

80 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-12-10

Study Completion Date

2027-12-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

-To measure SUVs by using different correction methods in oncological PET/CT imaging.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

-To compare between SUV measurements in the tumor and liver using different standardizing parameters such as: body weight, lean body mass and body surface area.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Cancer Patients Referred to do PET/CT Study

Keywords

Explore important study keywords that can help with search, categorization, and topic discovery.

SUV measurements , correction, PET/CT

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

PET/CT with 18-FDG

* Patients will fast for at least 4 hrs before imaging with blood glucose level (\<200 mg/dl) before intravenous administration of F18-FDG.
* Imaging will be performed approximately 45 to 60 min after 18F-FDG injection, an imaging field of view from the base of skull to mid-thighs with the arms above the head whenever possible is used or otherwise the arms are positioned beside the body.

Intervention Type DEVICE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Cancer patients (\> 18 years old) referred to nuclear medicine unit to do F18-FDG PET/CT study.

Exclusion Criteria

* Patients \< 18 years old.
* Patients with increased FDG uptake on tissue associated with non-malignant causes such as diffuse bone marrow FDG uptake or inflammatory.
* Patients with extensive metastasis.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Assiut University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Aya Kamel Hamed Ahmed

Resident doctor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Hanan Gamal Eldin Mostafa, Professor, doctor

Role: STUDY_CHAIR

Assiut University

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

HebatAllah Ahmed AbdelRaoof Askar, Assistant Professor, doctor

Role: CONTACT

Phone: +2001003040898

Email: [email protected]

Aya Kamel Hamed Ahmed, Resident doctor

Role: CONTACT

Phone: +2001097763423

Email: [email protected]

References

Explore related publications, articles, or registry entries linked to this study.

Kim CK, Gupta NC, Chandramouli B, Alavi A. Standardized uptake values of FDG: body surface area correction is preferable to body weight correction. J Nucl Med. 1994 Jan;35(1):164-7.

Reference Type RESULT
PMID: 8271040 (View on PubMed)

Nakaichi T, Funamoto K, Yamashita S, Yamamoto H, Yokoyama K. Clinical Usefulness of Standardized Uptake Value Normalized to Lean Body Mass Measured Using a Body Composition Analyzer. Cureus. 2025 May 30;17(5):e85089. doi: 10.7759/cureus.85089. eCollection 2025 May.

Reference Type RESULT
PMID: 40589668 (View on PubMed)

Azmi NHM, Suppiah S, Liong CW, Noor NM, Said SM, Hanafi MH, et al. Reliability of standarized uptake value normalized to lean body mass using the liver as a reference organ, in contrast-enhanced 18F-FDG PET/CT imaging. Radiography. 2018;24(2):112-117. doi:10.1016/j.radi.2017.09.006.

Reference Type RESULT

Ahmed A, Ali M, Salah H, Eisa RE, Mohieldin H, Omer H, et al. Evaluation of uptake values of FDG: Body surface area Vs. body weight correction. Radiat Phys Chem. 2022;201:110482. doi:10.1016/j.radphyschem.2022.110482 .

Reference Type RESULT

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

SUV measurements in PET/CT

Identifier Type: -

Identifier Source: org_study_id