Effect of Manual Lymphatic Drainage on Muscle Fatigue in Female 11-a-side Football Players

NCT ID: NCT07274033

Last Updated: 2025-12-10

Basic Information

• Recruitment Status: RECRUITING
• Clinical Phase: NA
• Total Enrollment: 11 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2025-11-17
• Study Completion Date: 2026-07-30

Brief Summary

This clinical trial investigates the effectiveness of manual lymphatic drainage (MLD) in accelerating recovery following induced fatigue in female football players. The study integrates objective performance measurements using linear encoders with anthropometric assessments and psychophysiological evaluations. It aims to quantify the impact of MLD on neuromuscular recovery, muscle edema, and perceived fatigue, considering sex-specific physiological factors and the influence of sleep and psychological stress. The findings will contribute to developing non-invasive, individualized recovery strategies to enhance performance and reduce injury risk in women's football.

Detailed Description

This study aims to assess the effectiveness of manual lymphatic drainage (MLD) as a recovery strategy following induced fatigue in female football players. The intervention is applied immediately after a standardized fatigue protocol using a linear encoder to objectively measure performance decline. The study adopts a multidimensional approach, integrating biomechanical, physiological, and psychometric variables to evaluate recovery.

Participants will undergo three experimental sessions involving a fatigue protocol followed by either MLD or control conditions. Performance will be assessed through guided machine squats, measuring the number of repetitions and time until a 20% velocity loss. Thigh circumference will be measured pre- and post-intervention to monitor fluid shifts and potential edema. Subjective recovery perception will be recorded, and emotional state will be evaluated using the Hospital Anxiety and Depression Scale (HADS). Sleep quality will be assessed using the Pittsburgh Sleep Quality Index (PSQI) to explore its influence on fatigue and recovery response.

This trial addresses the need for non-invasive, efficient recovery strategies tailored to female athletes, considering sex-specific physiological and psychological factors. The findings may contribute to optimizing post-exercise recovery protocols and reducing injury risk in women's football.

Conditions

Women

Study Design

• Allocation Method: NA
• Intervention Model: SINGLE_GROUP
• Primary Study Purpose: PREVENTION
• Blinding Strategy: NONE

Study Groups

Manual Lymphatic Drainage Group

The study consists of three visits. During the first visit, participants are informed about the study, eligibility criteria are verified, informed consent is obtained, and baseline assessments are conducted using psychophysiological questionnaires and thigh circumference measurements. In the second visit, assessments are repeated and fatigue is induced through guided squats at 50-60% of estimated 1RM, monitored via a linear encoder. Fatigue is defined as a 20% loss in execution velocity. Immediately after fatigue induction, manual lymphatic drainage (MLD) is applied for 10 minutes (5 minutes per quadriceps), following Emil Vodder's standardized technique. Post-intervention, performance testing and measurements are repeated. The third visit, conducted 15 days later, serves as a follow-up to evaluate sustained effects without further intervention, repeating the fatigue protocol and all assessments.

Group Type: EXPERIMENTAL

Manual lymphatic draige

Intervention Type: OTHER

This method, part of complex decongestive physiotherapy, involves gentle massage techniques that stimulate lymphatic circulation and venous return. MLD promotes lymph fluid mobilization, increases lymphangiomotor activity, and has positive effects on the immune system. Its application has shown to reduce limb edema, decrease muscle fatigue, and raise pain thresholds. Moreover, the gentle touch during MLD activates cutaneous receptors that influence the parasympathetic nervous system, producing physiological changes such as reduced heart rate, blood pressure modulation, and increased muscle strength.

Interventions

Manual lymphatic draige

This method, part of complex decongestive physiotherapy, involves gentle massage techniques that stimulate lymphatic circulation and venous return. MLD promotes lymph fluid mobilization, increases lymphangiomotor activity, and has positive effects on the immune system. Its application has shown to reduce limb edema, decrease muscle fatigue, and raise pain thresholds. Moreover, the gentle touch during MLD activates cutaneous receptors that influence the parasympathetic nervous system, producing physiological changes such as reduced heart rate, blood pressure modulation, and increased muscle strength.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Female athletes actively participating in 11-a-side football, either federated or official team members.
• Age ≥ 16 years to 20 years old.
• Regular training (≥ 3 sessions per week) or active competition
• No food intake within 3 hours prior to evaluation (to standardize the influence of digestion on performance).
• No acute lower limb injury in the past 3 months.
• Availability to attend all three study visits.
• Signed informed consent; for participants under 18, parental consent is also required.

Exclusion Criteria

• History of deep vein thrombosis
• Decompensated heart failure
• Active lower limb infection
• Pregnancy
• Recent lower limb surgery (< 3 months), or any medical contraindication to receiving manual lymphatic drainage (MLD).
• Failure to comply with the fasting requirement prior to performance testing.

• Minimum Eligible Age: 16 Years
• Maximum Eligible Age: 20 Years
• Eligible Sex: FEMALE
• Accepts Healthy Volunteers: Yes

Sponsors

Camilo Jose Cela University

OTHER

Sponsor Role: lead

Responsible Party

Edurne Úbeda D'Ocasar

Doctor Edurne Úbeda D'Ocasar

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Edurne Úbeda Docasar, Doctor

Role: PRINCIPAL_INVESTIGATOR

University Camilo José Cela

Locations

University of Camilo José Cela

Madrid, , Spain

Site Status: RECRUITING

Countries

Spain

Central Contacts

Edurne Úbeda D'Ocasar, Doctor

Role: CONTACT

eubeda@ucjc.edu

+34 8153131 ext. 19217

Facility Contacts

Edurne Úbeda Docasar

Role: primary

eubeda@ucjc.edu

Other Identifiers

UCJCDLMF

Identifier Type: -

Identifier Source: org_study_id