Prediabetes and Metabolic Parameters Among Young Adults at Assiut University Hospital

NCT ID: NCT07259954

Last Updated: 2025-12-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Total Enrollment

120 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-12-01

Study Completion Date

2028-02-01

Brief Summary

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Prediabetes is a major public health problem that increases the risk of developing type 2 diabetes mellitus and cardiovascular complications. Young adults represent an important age group in which early detection and intervention may prevent progression of the disease. The present study aims to identify factors associated with prediabetes and metabolic complications, and classify individuals based on clinical and biochemical profiles according to insulin resistance, dyslipidemia and fatty liver. This is an observational, cross-sectional study that will be conducted at Assiut University Hospital. Data will be collected through clinical examination, laboratory investigations, and assessment of metabolic profiles.

Detailed Description

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Conditions

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PreDiabetes

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Group A impaired glucose tolerance_Group B - Impaired Fasting Glucose Group C - Impaired HbA1c

No intervention

Intervention Type OTHER

Participants will be classified into groups based on impaired fasting glucose, impaired post-prandial glucose, or impaired HbA1c according to ADA criteria

Interventions

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No intervention

Participants will be classified into groups based on impaired fasting glucose, impaired post-prandial glucose, or impaired HbA1c according to ADA criteria

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* adults diagnosed with prediabetes

Exclusion Criteria

* previous diagnosis of overt diabetes
* other causes of CKD (e.g. urinary tract infection)
* other causes of liver disease (e.g. HBV infection),
* use of medications that alter glucose or lipid metabolism (e.g. corticosteroids),
* current pregnancy
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Assiut University

OTHER

Sponsor Role lead

Responsible Party

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Heba Gamal Ali Mohamed

Internal medicine ,assuit university hospital

Responsibility Role PRINCIPAL_INVESTIGATOR

References

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http://doi.org/10.1007/s00125-013-2902-4

Reference Type BACKGROUND

http://doi.org/10.1136/bmj.g4485

Reference Type BACKGROUND

http://doi.org/10.1007/s00125-009-1443-3

Reference Type BACKGROUND

http://doi.org/10.2337/dc08-1264

Reference Type BACKGROUND

http://doi.org/10.1016/j.diabres.2007.05.004

Reference Type BACKGROUND

http://doi.org/10.2337/diabetes.52.6.1475

Reference Type BACKGROUND

http://doi.org/10.1136/bmj.i5953

Reference Type BACKGROUND

http://doi.org/10.1056/NEJMoa012512

Reference Type BACKGROUND

http://doi.org/10.1016/S0140-6736(12)60525-X

Reference Type BACKGROUND

http://doi.org/10.2337/dc10-0679

Reference Type BACKGROUND

http://doi.org/10.2337/diacare.2951130

Reference Type BACKGROUND

http://doi.org/10.2337/dc07-9920

Reference Type BACKGROUND

http://doi.org/10.1016/S0140-6736(12)60283-9

Reference Type BACKGROUND

International Diabetes Federation. IDF Diabetes Atlas. 10th ed. Brussels: IDF; 2021. http://www.diabetesatlas.org

Reference Type BACKGROUND

Related Links

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Other Identifiers

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AUH-MED-PREDIAB-2025

Identifier Type: -

Identifier Source: org_study_id

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