Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
RECRUITING
2000 participants
OBSERVATIONAL
2025-10-31
2028-09-01
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Metabolic syndrome and prediabetes are chronic multisystem disorders, and poor long-term control is closely associated with the development of various complications. Moreover, malnutrition and functional decline are common comorbid conditions that further impair quality of life and impose a substantial burden on healthcare resources.
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Validating Integrative Multi-omics Approaches in Metabolic Syndrome-related Diseases
NCT07248371
The Prevalence of Metabolic Syndrome and Its Associated Factors in an Urban City
NCT00308672
Investigation of Metabolomics Differences Between Metabolic Syndrome and Healthy Individuals in Taiwan
NCT06363864
Pancreatic Islet Function, Insulin Sensitivity, and Chronic Complications in Pre-Diabetes
NCT00172796
Heterogeneity of Diabetes: Integrated Muli-Omics to Identify Physiologic Subphenotypes and Evaluate Targeted Prevention
NCT06682351
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
The condition is strongly influenced by dietary and lifestyle factors. Its core pathophysiological features are insulin resistance and central obesity, and there is a high degree of comorbidity between metabolic syndrome and prediabetes.
The establishment of a comprehensive cohort and database for individuals with metabolic syndrome and prediabetes will facilitate the systematic collection of metabolic profiles and disease-related biomarkers. This will enable longitudinal analyses of systemic and organ-specific complications, their incidence, and predictive determinants, thereby strengthening disease risk stratification and early identification.
This study aims to collect routine clinical, physiological, and nutritional data at regular intervals to examine associations among lifestyle behaviors, metabolic factors, physiological indicators, and the development of complications. Furthermore, it seeks to evaluate nutritional and functional status, identify potential prognostic biomarkers, and provide a foundation for individualized therapeutic approaches and integrated healthcare models.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
COHORT
PROSPECTIVE
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
2. Individuals clinically diagnosed by a physician as having metabolic syndrome (meeting at least three of the following five criteria) or prediabetes:
(A) Waist circumference: ≥ 90 cm in men or ≥ 80 cm in women, or body mass index (BMI) ≥ 27 kg/m².
(B) Fasting plasma glucose (AC): ≥ 100 mg/dL. (C) Blood pressure: Systolic blood pressure ≥ 130 mmHg or diastolic blood pressure ≥ 85 mmHg.
(D) Triglycerides (TG): ≥ 150 mg/dL. (E) High-density lipoprotein cholesterol (HDL-C): \< 40 mg/dL in men or \< 50 mg/dL in women.
3. Individuals meeting the definition of prediabetes, defined as glycated hemoglobin (HbA1c) between 5.7% and 6.4%.
4. Participants who are willing to participate in the study and have signed written informed consent.
5. Participants who are able to complete basic physical examinations and assessment procedures.
Exclusion Criteria
2. Individuals unable to comply with the required assessments or study protocols.
3. Any other condition that, in the clinical judgment of the principal investigator, deems the individual unsuitable for participation.
18 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
National Taiwan University Hospital
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Principal Investigators
Learn about the lead researchers overseeing the trial and their institutional affiliations.
Chia-Wen Lu, Present Professor
Role: STUDY_CHAIR
Department of Family Medicine, National Taiwan University Hospital
Locations
Explore where the study is taking place and check the recruitment status at each participating site.
National Taiwan University Hospital
Taipei, Zhongzheng Dist, Taiwan
Countries
Review the countries where the study has at least one active or historical site.
Central Contacts
Reach out to these primary contacts for questions about participation or study logistics.
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
202509097RINB
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.