Diabetes Intervention Involving Person-centred Nutritional Education

NCT ID: NCT07258758

Last Updated: 2025-12-12

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

54 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-09-01

Study Completion Date

2027-06-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

The overall objective for this project is to evaluate the effects of a person-centred education intervention to promote a healthy, sustainable Nordic diet compared with the current practice of providing short dietary information on health outcomes of adults with Type 1 diabetes. The study will measure the intervention's impact on blood glucose levels, blood lipids, blood pressure, and adherence to a sustainable and healthy Nordic diet.

The main question the trial aims to answer is:

Does a person-centred nutritional education have an impact on glucose time in range for adults with Type 1 diabetes, compared with short dietary information?

The participants will:

* Attend either a person-centred nutrition education (intervention) or receive short dietary information (control group).
* Wear their sensor for continuous glucose monitoring (CGM) throughout the trial.
* Visit the clinic for data collection (blood samples and clinical checks) at the start and end of the trial.
* Keep a four-day food diary, fill out a food frequency questionnaire (FFQ) and estimate their food enjoyment at the start and end of the trial.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

The Diabetes Intervention Involving Person-centred Nutritional Education (DINE) trial is a single-centre, randomized parallel group study conducted in Sweden. The trial aims to compare a person-centred intervention involving nutritional education with the current practice of providing short dietary information to adults with Type 1 diabetes. The study period is six months and will assess the effectiveness of the intervention in a real-world setting, rather than under controlled conditions. Due to the active involvement of participants, blinding of study personnel or participants is not possible.

To determine the sample size, a power calculation was performed using the primary endpoint, 'blood glucose time in range' (TIR). The calculation is based on a clinically relevant change in TIR (8%) from intervention to the six-month follow-up. The proposed enrolment is 54 participants to achieve sufficient power (80%) to test the primary hypothesis. Recruitment will continue until this number is reached. Assuming an 80% consent rate, we expect to enrol at least 54 participants within 12 months.

Participants in the intervention group will start with an individual pre-assessment with a registered dietitian, focusing on their preferences and values. This aims to build a partnership in care through the participant´s narrative. Next, they will attend an education session on the sustainable, healthy Nordic diet. During this session, the participant will develop an individual health plan together with the dietitian as part of shared decision-making. These handwritten plans will be copied, with one given to the participant and one kept by the dietitian for medical records.

The health plans will be reviewed twice during the study period, allowing for updates with new goals or more realistic targets. These updates will be documented by the dietitian. Participants will receive monthly text message reminders to enhance the intervention's efficacy.

Control group participants will receive short dietary information as part of routine clinical practice. The study duration for all participants is six months.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Diabetes Type 1

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized parallel group study
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

As the participants are actively involved in the education intervention, it is not possible to have a blinded trial, however each group will not receive information about the alternative group.

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Person-centred nutritional education

The participants in this arm will attend a person-centred intervention involving a pre-assessment focused on creating partnership in care. This is followed by a nutrition education session on the healthy Nordic diet, and a series of follow-up measures.

Group Type EXPERIMENTAL

Dietary intervention

Intervention Type BEHAVIORAL

A person-centred education focussed on creating partnerships in care and shared decision-making.

Short dietary information

The participants in this arm will receive short dietary information (brochure) at the same level as standard care.

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Dietary intervention

A person-centred education focussed on creating partnerships in care and shared decision-making.

Intervention Type BEHAVIORAL

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Type 1 Diabetes.
* Diabetes duration for more than 12 months at screening.
* Adults 18 years or older.
* HbA1c more than 57mmol/mol.
* Use of continuous glucose monitoring (CGM) sensor for more than three months at screening and during the study period.
* Use of basal and bolus insulin regimen for more than three months at screening and during the study period.
* Written Informed Consent.

Exclusion Criteria

* Women of childbearing potential: ongoing pregnancy or planned pregnancy during the study period.
* Cognitive impairment or other disease that study physician find non-compatible with participation.
* Planned change in glucose lowering treatment during study period (change of mealtime insulin analogue with same pharmacodynamic profile allowed).
* Planned change of CGM sensor during the study.
* Food allergies or intolerances that are incompatible with adhering to Nordic nutrition recommendations.
* Current or planned treatment with corticosteroids during the study (other than for replacement therapy).
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Lasarettet i Enköping

OTHER

Sponsor Role collaborator

Umeå University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Elisabeth Stoltz Sjöström

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Elisabeth Stoltz Sjöström, Associate professor

Role: PRINCIPAL_INVESTIGATOR

Department of Food, Nutrition and Culinary Science, Umeå University, Sweden

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Hospital of Enköping

Enköping, Uppland, Sweden

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

Sweden

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Sophie Rodebjer Cairns, Registered dietitian

Role: CONTACT

+46171418551

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Sophie Rodebjer Cairns, Registered dietitian

Role: primary

+46171418551

Role: backup

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

2024-04356-01

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Diabetic Educational Eating Plan
NCT00473811 COMPLETED PHASE1/PHASE2
Diabetes Education and A1c Study
NCT04806685 COMPLETED NA