Effect of HFNC on Incidence of Hypoxia During Sedated Gastrointestinal Endoscopy in Critical Patients
NCT ID: NCT07252102
Last Updated: 2026-01-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
450 participants
INTERVENTIONAL
2025-11-20
2026-12-30
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
SINGLE
Study Groups
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High-flow nasal catheter oxygen
High-flow nasal catheter oxygen
Before induction of anesthesia, connect the Airvo2 (HFNC high flow device) special nasal cannula to inhale oxygen, and preoxygenate with an oxygen flow rate of 6L /min. After induction of anesthesia, adjust the oxygen flow rate to 60L /min, oxygen concentration 100%, oxygen temperature 37℃ until the end of gastrointestinal endoscopy.
Regular nasal catheter oxygen
regular nasal catheter oxygen
Before anesthesia induction, a disposable nasal catheter oxygen inhalation device (covered by HFNC nasal catheter and blinded to the patient) was connected to an oxygen source for pre-oxygen inhalation, 6L/min. After induction of anesthesia, oxygen was continued for 6L/min until the end of gastroenteroscopy.
Interventions
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High-flow nasal catheter oxygen
Before induction of anesthesia, connect the Airvo2 (HFNC high flow device) special nasal cannula to inhale oxygen, and preoxygenate with an oxygen flow rate of 6L /min. After induction of anesthesia, adjust the oxygen flow rate to 60L /min, oxygen concentration 100%, oxygen temperature 37℃ until the end of gastrointestinal endoscopy.
regular nasal catheter oxygen
Before anesthesia induction, a disposable nasal catheter oxygen inhalation device (covered by HFNC nasal catheter and blinded to the patient) was connected to an oxygen source for pre-oxygen inhalation, 6L/min. After induction of anesthesia, oxygen was continued for 6L/min until the end of gastroenteroscopy.
Eligibility Criteria
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Inclusion Criteria
2. Patients undergoing elective gastroenteroscopy or treatment;
3. ASA grade Ⅲ\~Ⅳ;
4. 18 kg/m2≤BMI≤28kg/m2;
5. The operation time of gastroenteroscopy is expected to be no more than 60min;
6. Clearly understand, voluntarily participate in the study, and have informed consent from myself or my family members.
Exclusion Criteria
2. acute respiratory infections and asthma attacks;
3. Patients diagnosed with COPD;
4. Clear difficult airway;
5. Acute upper gastrointestinal bleeding with shock;
6. Gastrointestinal obstruction with gastric content retention;
7. Allergic to sedatives such as propofol;
8. Persons with no capacity for civil conduct such as cognitive dysfunction.
18 Years
80 Years
ALL
No
Sponsors
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Zhejiang University
OTHER
Responsible Party
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Diansan Su
Chief, Department of Anesthesiology, the First Affiliated Hospital of Zhejiang University School of Medicine
Locations
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Shenzhen Hospital of Southern Medical University
Shenzhen, Guangdong, China
Cancer Hospital Chinese Academy of Medical Sciences, Shenzhen Center
Shenzhen, Guangdong, China
The First Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou, Zhejiang, China
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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ZJU2025C036
Identifier Type: -
Identifier Source: org_study_id
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