Impact of Prepartum Intravenous Fluid Intake on Newborn Weight Loss in the First Days of Life

NCT ID: NCT07243054

Last Updated: 2025-11-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-03-01

Study Completion Date

2025-11-30

Brief Summary

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At birth, the infant's weight was measured daily to assess the adequacy of nutritional intake. This indicator can be influenced by various factors related to the mother, her pregnancy, as well as medical interventions during the pre-delivery phase, such as pre-partum maternal fluid intakes, and the subsequent feeding method chosen for the newborn infant. This study aimed at exploring the association between maternal vascular fluid loading during labor in the pre-partum period and neonatal weight loss in the first two days of life. The study focuses on infants fedded with infant formula.

This observational, retrospective, single-center study was carried out at the Amiens University Hospital Center. The participants were mothers aged 18 and older, hospitalized in the maternity ward following full-term delivery (\> 37 weeks of gestation). Data were collected through the medical records of the patient and their newborn.

The investigators hypothesize that a relationship may exist between maternal pre-partum vascular fluid loading and neonatal weight loss in the first two days of life, in infants fed with infant formula. These results could raise awareness and help adapt medical and parental approaches to neonatal weight loss.

Detailed Description

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Conditions

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Vascular Filling Newborn Weight Loss Jaundice Respiratory Distress

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Full-term delivery (≥37+0 SA)
* Singleton pregnancy
* Mother over 18 years of age
* Infant formula feeding exclusively in the maternity ward for the first 2 days

Exclusion Criteria

* Mother under guardianship
* Mother who does not understand French
* Mother objecting to her personal data being reused for research purposes
* Incomplete or incorrectly completed patient medical record
* Mixed or exclusive breastfeeding
* Mother presenting a hemodynamic disorder in the 12 hours preceding delivery, requiring a filling specifically for this reason
* Child with renal pathology or uropathy
* Children with cleft lip, palate or labio-palate
Minimum Eligible Age

18 Years

Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Centre Hospitalier Universitaire, Amiens

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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CHU Amiens Picardie

Amiens, Picardie, France

Site Status RECRUITING

Countries

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France

Central Contacts

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Pierre Tourneux, Pr

Role: CONTACT

33+3 22 08 76 04

Facility Contacts

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Pierre TOURNEUX, PhD

Role: primary

+33322668652

Other Identifiers

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PI2025_843_0037

Identifier Type: -

Identifier Source: org_study_id

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