Fluid Balance Study in Sick Neonates

NCT ID: NCT00962754

Last Updated: 2014-05-07

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

170 participants

Study Classification

INTERVENTIONAL

Study Start Date

2009-06-30

Study Completion Date

2010-03-31

Brief Summary

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The purpose of this study is to determine if routinely recording fluid balance in sick neonates admitted to the pediatric ward is reliable and useful. The investigators' hypothesis is that it is not useful and reliable.

Detailed Description

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Fluid balance charts are commonly used, in the Netherlands, to assess patient fluid volume status. Some disadvantages of recording fluid intake and output are that it is time-consuming and complex. If it would give reliable and accurate information about the fluid volume status there would be a good reason for all this effort. In the few researches that have investigated this subject a low correlation has been found between the fluid balance and the weight changes of an adult patient. Own experience gives reasons to doubt about the reliability of the fluid balance in children, not rarely there is a discrepancy between the fluid balance and the weight measurement. We are interested in the relevance of recording fluid balance in neonates.

Conditions

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Very Low Birth Weight Infant

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

SINGLE

Participants

Study Groups

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physician insight fluid balance

physician has insight in fluid balance chart, this is standard practice

Group Type NO_INTERVENTION

No interventions assigned to this group

fluid balance data masked to physician

physician no insight in the fluid balance chart

Group Type EXPERIMENTAL

physician no insight in the fluid balance chart

Intervention Type PROCEDURE

physician had no insight in the fluid balance chart during the first 3 days of admission of the patient when the balance is recorded

Interventions

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physician no insight in the fluid balance chart

physician had no insight in the fluid balance chart during the first 3 days of admission of the patient when the balance is recorded

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Sick neonates admitted to the neonatal ward

Exclusion Criteria

* Admitted elsewhere before admission to the neonatal ward
* Indication for recording fluid balance
* Impossibility to measure the weight every day
* No consent parents
Maximum Eligible Age

28 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Princess Amalia Children's Clinic

OTHER

Sponsor Role lead

Responsible Party

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Jolita Bekhof

MD, Pediatrician

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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J Bekhof, pediatrician

Role: STUDY_DIRECTOR

Princess Amalia Children's Clinic

Y v Asperen, MD

Role: PRINCIPAL_INVESTIGATOR

University of Groningen

Locations

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Princess Amalia Children's Clinic

Zwolle, Overijssel, Netherlands

Site Status

Countries

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Netherlands

References

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Daffurn K, Hillman KM, Bauman A, Lum M, Crispin C, Ince L. Fluid balance charts: do they measure up? Br J Nurs. 1994 Sep 8-21;3(16):816-20. doi: 10.12968/bjon.1994.3.16.816.

Reference Type BACKGROUND
PMID: 7950261 (View on PubMed)

Chung LH, Chong S, French P. The efficiency of fluid balance charting: an evidence-based management project. J Nurs Manag. 2002 Mar;10(2):103-13. doi: 10.1046/j.0966-0429.2001.00296.x.

Reference Type BACKGROUND
PMID: 11882111 (View on PubMed)

Wise LC, Mersch J, Racioppi J, Crosier J, Thompson C. Evaluating the reliability and utility of cumulative intake and output. J Nurs Care Qual. 2000 Apr;14(3):37-42. doi: 10.1097/00001786-200004000-00005.

Reference Type BACKGROUND
PMID: 10826233 (View on PubMed)

Eastwood GM. Evaluating the reliability of recorded fluid balance to approximate body weight change in patients undergoing cardiac surgery. Heart Lung. 2006 Jan-Feb;35(1):27-33. doi: 10.1016/j.hrtlng.2005.06.001.

Reference Type BACKGROUND
PMID: 16426933 (View on PubMed)

Mank A, Semin-Goossens A, Lelie Jv, Bakker P, Vos R. Monitoring hyperhydration during high-dose chemotherapy: body weight or fluid balance? Acta Haematol. 2003;109(4):163-8. doi: 10.1159/000070964.

Reference Type BACKGROUND
PMID: 12853687 (View on PubMed)

Pflaum SS. Investigation of intake-output as a means of assessing body fluid balance. Heart Lung. 1979 May-Jun;8(3):495-8.

Reference Type BACKGROUND
PMID: 254670 (View on PubMed)

Scales K, Pilsworth J. The importance of fluid balance in clinical practice. Nurs Stand. 2008 Jul 30-Aug 5;22(47):50-7; quiz 58, 60. doi: 10.7748/ns2008.07.22.47.50.c6634.

Reference Type BACKGROUND
PMID: 18777823 (View on PubMed)

Bekhof J, van Asperen Y, Brand PL. Usefulness of the fluid balance: a randomised controlled trial in neonates. J Paediatr Child Health. 2013 Jun;49(6):486-92. doi: 10.1111/jpc.12214. Epub 2013 May 2.

Reference Type DERIVED
PMID: 23635344 (View on PubMed)

Other Identifiers

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NL26894.075.09

Identifier Type: -

Identifier Source: org_study_id

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