Effect of Developmental Care on Very Low Birth Weight Infants

NCT ID: NCT06515574

Last Updated: 2025-01-20

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

1600 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-08-30

Study Completion Date

2027-12-01

Brief Summary

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The goal of this clinical trial is to learn if developmental care works when implemented in very low birth weight infants. The main questions it aims to answer are:

* Does developmental care shorten the length of hospital stay in the very low birth weight infants?
* Does developmental care increase the opportunity of family centered care in the very low birth weight infants? The clinical trial will use a 36-month stepped-wedge cluster-randomised trial conducted across 40 Neonatal intensive care units . A developmental care bundle will be tailored to meet the identified needs of participating NICUs.

Detailed Description

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Developmental care in the NICU focuses on creating a nurturing environment that supports the physical, emotional, and developmental needs of premature infants. This approach includes strategies like minimizing unnecessary noise and light, ensuring appropriate positioning and handling of infants, promoting skin-to-skin contact, and facilitating parental involvement in care.

The clinical trial investigates the effectiveness of developmental care in very low birth weight (VLBW) infants. The primary objectives are to determine whether developmental care can (1) reduce the length of hospital stay and (2) enhance the opportunity for family-centered care in these infants. The study employs a 36-month stepped-wedge cluster-randomised trial design, involving 40 Neonatal Intensive Care Units (NICUs).

In this trial, all NICUs will eventually receive the intervention, but the order in which they start implementing the developmental care bundle will be randomized. This approach allows each NICU to serve as its own control, comparing outcomes before and after the intervention.

Data collection will occur at multiple time points before and after the implementation of the developmental care bundle, enabling a comprehensive analysis of its impact. By tailoring interventions to each NICU's specific context and needs, the study aims to generate robust evidence on the benefits of developmental care for VLBW infants and their families.

Conditions

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Intervention

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

SEQUENTIAL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Developmental care

In stage 1, participant in this arm will receive the developmental care

Group Type EXPERIMENTAL

developmental care

Intervention Type BEHAVIORAL

Individualized Developmental Care that includes the light, noise, sleep, etc.

Usual care

Participant in this arm will receive the usual care

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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developmental care

Individualized Developmental Care that includes the light, noise, sleep, etc.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

1. Birth weights less than 1500 g
2. Admitted or transported to a level III NICU within 24h of birth
3. OI\>30

Exclusion Criteria

1. Severe congenital malformations
2. various chromosomal disorders
3. genetic metabolic diseases,
4. severe neurological disorders
Minimum Eligible Age

0 Days

Maximum Eligible Age

30 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Children's Hospital of Fudan University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Children's hospital of Fudan university

Shanghai, Shanghai / 上海, China

Site Status RECRUITING

Children's Hospital of Fudan University

Shanghai, Shanghai Municipality, China

Site Status NOT_YET_RECRUITING

Countries

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China

Central Contacts

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Lyu Tianchan

Role: CONTACT

18017590870

Facility Contacts

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LYU tianchan

Role: primary

02164935075

Xiaojing Hu, PhD

Role: primary

18017590869

Other Identifiers

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20240610

Identifier Type: -

Identifier Source: org_study_id

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