The Effect of Family Integrated Care on Melatonin Level in Very Low Birth Weight Infants

NCT ID: NCT05483231

Last Updated: 2023-08-14

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

64 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-12-01

Study Completion Date

2024-04-30

Brief Summary

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This study will explore the effect of Family integrated care (FICare) on the level of melatonin and other clinical outcomes in very low birth weight infants (VLBWIs) by integrating families into the neonatal intensive care unit (NICU) care team and participating in the daily care of VLBWIs, as well as the influence of FIcare on parents' outcomes.

Detailed Description

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This study is a multicenter randomized controlled trial which mainly explores the effect of Family integrated care (FICare) on melatonin levels in very low birth weight infants (VLBWIs) in neonatal intensive care unit (NICU). The intervention group will use a FICare intervention program, mainly for families who have been fully trained by the NICU professional team and need to stay in the NICU to accompany and care for the VLBWIs for not less than 6 hours a day for at least 3 weeks. All non-medical care measures and developmental supportive care will be provided by parents as much as possible. The control group received routine nursing interventions in which all non-medical interventions are led by NICU staff and without parental involvement. The level of melatonin, clinical and parental outcomes in VLBWIs are compared between the intervention group and the control group to evaluate the effect of FICare intervention program.

Conditions

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Very Low Birth Weight Infant

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Family integrated care intervention group

Provide Family integrated care for very low birth weight infants in the NICU.

Group Type EXPERIMENTAL

Family integrated care intervention group

Intervention Type BEHAVIORAL

If the very low birth weight infants' vital signs are stable at 32 weeks of corrected gestational age, parents who have been fully trained will provide all non-medical care measures and developmental care for the VLBWIs in the NICU for not less than 6 hours per day for at least 3 weeks, and other medical practice and care measures will be the same as the routine group.

Routine nursing care group

Perform routine nursing care for very low birth weight infants in the NICU.

Group Type OTHER

Routine nursing care group

Intervention Type BEHAVIORAL

Routine practice and in-hospital education will be given to the very low birth weight infants and parents. All care measures will be led by the nursing staff, without the participation of parents.

Interventions

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Family integrated care intervention group

If the very low birth weight infants' vital signs are stable at 32 weeks of corrected gestational age, parents who have been fully trained will provide all non-medical care measures and developmental care for the VLBWIs in the NICU for not less than 6 hours per day for at least 3 weeks, and other medical practice and care measures will be the same as the routine group.

Intervention Type BEHAVIORAL

Routine nursing care group

Routine practice and in-hospital education will be given to the very low birth weight infants and parents. All care measures will be led by the nursing staff, without the participation of parents.

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Birth weight \< 1500g;
* Gestational age \< 32w;
* Admit within 24 hours of birth;
* The parents are conscious and able to cooperate, have certain learning and reading comprehension skills, and are capable of caring for their babies. They are committed to receiving training and caring for their babies for not less than 6 hours a day for at least 21 days;
* Voluntarily participate in this study and sign informed consent.

Exclusion Criteria

* Newborns who require palliative care or surgical intervention;
* OI (oxygenation index) \<300 ;
* Newborns with severe congenital malformations;
Minimum Eligible Age

0 Hours

Maximum Eligible Age

24 Hours

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Children's Hospital of Fudan University

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Xiaojing Hu, PhD

Role: PRINCIPAL_INVESTIGATOR

Children's Hospital of Fudan University

Locations

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Children's Hospital of Fudan University

Shanghai, Shanghai Municipality, China

Site Status

Countries

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China

Central Contacts

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Yi Zhang, Master

Role: CONTACT

+8618071608186

Xiaojing Hu, PhD

Role: CONTACT

+8618017590869

Facility Contacts

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Xiaojing Hu, PhD

Role: primary

+8618017590869

Yi Zhang, Master

Role: backup

+8618071608186

Other Identifiers

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2021-453

Identifier Type: -

Identifier Source: org_study_id

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