Pediatric GI Endoscopy at Assiut University

NCT ID: NCT07239934

Last Updated: 2025-11-20

Basic Information

• Recruitment Status: NOT_YET_RECRUITING
• Total Enrollment: 150 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2026-01-01
• Study Completion Date: 2027-06-01

Brief Summary

1. To evaluate the diagnostic role, and outcomes of upper and lower gastrointestinal (GI) endoscopy in identifying gastrointestinal disorders among infants and pediatric patients attending Assiut University Children Hospital.

2. To determine which pediatric patients require endoscopy as part of the diagnostic process.

3. To assess the safety and effectiveness of endoscopic procedures in the detection and management of various gastrointestinal disorders among pediatric patients at Assiut University Children Hospital.

Detailed Description

Pediatric endoscopy plays a pivotal role in the diagnosis and management of various gastrointestinal and hepatological disorders in children.It allows doctors to see inside the digestive system, identify problems, and sometimes even treat them during the same procedure. It is a rapidly evolving field, with continuous advancements in both endoscopic technology and procedural skills, making it a safe, effective, and reliable diagnostic and therapeutic tool. Today, pediatric endoscopy is considered an essential part of evaluating and treating a wide range of gastrointestinal conditions in children. Accurate and timely diagnosis of gastrointestinal disorders is critical to prevent complications, reduce morbidity, and ensure appropriate management. These disorders are among the most common health problems affecting children worldwide. They often present with a wide variety of symptoms, including failure to thrive, unexplained anemia, recurrent vomiting, dysphagia (difficulty swallowing), acute epigastric pain, foreign body ingestion, hematemesis (vomiting blood), melena (black, tarry stools), abdominal pain, rectal bleeding, bloody diarrhea, and chronic diarrhea. At Assiut University Children Hospital, a major tertiary care center serving Upper Egypt. In recent years, there has been growing use of gastrointestinal endoscopy as a main method for diagnosing and treating various GI conditions. IT includes foreign body removal, management of caustic ingestion injuries, treatment of esophageal strictures, assessment of gastroesophageal reflux disease (GERD) severity, diagnosis of Helicobacter pylori infection through endoscopic biopsy, evaluation of eosinophilic esophagitis, management of variceal and non-variceal gastrointestinal bleeding such as deep ulcerations and gastroduodenal vascular malformations. In addition, ileocolonoscopy is commonly performed to assess lower gastrointestinal disorders such as juvenile polyps, inflammatory bowel disease (IBD), allergic colitis, vascular malformations, and infectious colitis.

Conditions

Chronic Diarrhea; Persistent Vomitting; Gastrointestinal Bleeding; Dysphagia; Foreign Body Ingestion; Failure to Thrive; Pediatric Inflammatory Bowel Disease

Study Design

• Observational Model Type: OTHER
• Study Time Perspective: PROSPECTIVE

Interventions

Gastrointestinal Endoscopy

Children undergoing evaluation for gastrointestinal symptoms (such as abdominal pain, bleeding, vomiting, chronic diarrhea, suspected foreign body ingestion, or growth failure) will undergo diagnostic gastrointestinal endoscopy (upper or lower as clinically indicated). The procedure will be performed under appropriate sedation/anesthesia using a standard pediatric endoscope. During endoscopy, visualization of the mucosa will be carried out, and biopsies may be taken if needed for histopathological examination.

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• Children aged from 1day to 18 years undergoing diagnostic endoscopy.

Exclusion Criteria

• Incomplete patient data.
• Patients undergoing follow-up procedures.

• Minimum Eligible Age: 1 Day
• Maximum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Assiut University

OTHER

Sponsor Role: lead

Responsible Party

Aml Shaban Mohamed Farghly

Resident of Pediatrics, Assiut University Children's Hospital

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Khalid Abd elaziz, MD

Role: STUDY_DIRECTOR

Assiut University, Faculty of Medicine, Children Hospital

rehab ibrahim, MD

Role: STUDY_DIRECTOR

Assiut University, Faculty of Medicine, Children Hospital

Locations

Endoscopic Centre at Assiut University Children Hospital

Asyut, Asyut Governorate, Egypt

Countries

Egypt

Central Contacts

Aml Shaban, MBBS

Role: CONTACT

amaal.17305794@med.aun.edu.eg

+201066154318

Rehab Ibrahim, MD

Role: CONTACT

+20 10 09272624

References

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Reference Type: RESULT

PMID: 30058633 (View on PubMed)

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Reference Type: RESULT

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Reference Type: RESULT

PMID: 27617420 (View on PubMed)

Fachler T, Shteyer E, Orlanski Meyer E, Shemasna I, Lev Tzion R, Rachman Y, Bergwerk A, Turner D, Ledder O. Pediatric Gastrointestinal Endoscopy: Diagnostic Yield and Appropriateness of Referral Based on Clinical Presentation: A Pilot Study. Front Pediatr. 2021 Oct 29;9:607418. doi: 10.3389/fped.2021.607418. eCollection 2021.

Reference Type: RESULT

PMID: 34778118 (View on PubMed)

Ngo PD, Lightdale JR. Advances in Pediatric Endoscopy. Gastroenterol Clin North Am. 2024 Dec;53(4):539-555. doi: 10.1016/j.gtc.2024.08.010. Epub 2024 Sep 30.

Reference Type: RESULT

PMID: 39489574 (View on PubMed)

Franciosi JP, Fiorino K, Ruchelli E, Shults J, Spergel J, Liacouras CA, Leonard M. Changing indications for upper endoscopy in children during a 20-year period. J Pediatr Gastroenterol Nutr. 2010 Oct;51(4):443-7. doi: 10.1097/MPG.0b013e3181d67bee.

Reference Type: RESULT

PMID: 20562722 (View on PubMed)

Other Identifiers

endoscopy in AUCH

Identifier Type: -

Identifier Source: org_study_id