Prevalence of Inappropriate Prescriptions and Omitted Therapies in Hospitalized Elderly: STOPP/START Criteria Analysis

NCT ID: NCT07202962

Last Updated: 2025-10-02

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 100 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2024-07-17
• Study Completion Date: 2024-12-31

Brief Summary

Evaluate the prevalence of potentially inappropriate prescriptions (PIPs) and potential omitted prescriptions (PPOs) in elderly patient upon admission to the acute geriatric department, based on adherence or non-adherence to the recommendations specified in STOPP and START criteria.

Conditions

Polypharmacy (People Under Treatment With 5 or More Drugs); Elderly (People Aged 65 or More); Deprescribing; Hospitalization

Study Design

• Observational Model Type: COHORT
• Study Time Perspective: PROSPECTIVE

Interventions

medication review and deprescribing

The study protocol includes the following assessments:

• T0: first data collection upon admission to the ward;
• T1 assessment: pharmacological review at discharge. Subjects who meet all study eligibility criteria will come consecutively enrolled in the study during admission to the department (T0).

By consulting the electronic health record, interviewing patients and family members and personal documentation, the following data will be collected:

• Remote and immediate pathological history;
• Family and social history;
• Home therapy;
• BRIEF-MPI. Home therapy and therapy suggested at discharge will be compared with the STOPPandSTART criteria to evaluate the prevalence of potential therapies inappropriate and to study possible interactions and contraindications pharmacological and for reporting possible adverse reactions to drugs. The prevalence and possible prevalence of each individual STOPPandSTART criterion will be assessed association with other variables of interest.

Intervention Type: DRUG

Eligibility Criteria

Inclusion Criteria

• Elderly patients (aged >75 years) admitted to the Geriatrics Department at Santorso, Alto Vicentino Hospital.
• Currently undergoing pharmacological treatment at the time of admission.

Exclusion Criteria

• Patients placed in palliative therapy upon admission to the department due to incurability of the underlying pathologies

• Minimum Eligible Age: 75 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Regione del Veneto - AULSS n. 7 Pedemontana

OTHER

Sponsor Role: lead

Responsible Party

Luca Pellizzari

Director of Geriatrics

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Luca Pellizzari Dr. Pellizzari, DR

Role: PRINCIPAL_INVESTIGATOR

Regione del Veneto - AULSS n. 7 Pedemontana

Locations

Regione del Veneto - AULSS n. 7 Pedemontana

Santorso, Vicenza, Italy

Countries

Italy

Other Identifiers

1239

Identifier Type: -

Identifier Source: org_study_id