Prediction of Postoperative Mortality in Patients Undergoing Non-cardiac Surgery: Development and Validation of the Surgical Mortality Model

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

642377 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-07-30

Study Completion Date

2025-01-20

Brief Summary

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This study aims to develop and validate a simple, accurate model to predict mortality after non-cardiac surgery.

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Detailed Description

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This retrospective multi-center cohort study aimed to develop and externally validate a predictive model for postoperative mortality in adult patients undergoing non-cardiac surgery. The development cohort included patients from Asan Medical Center, and validation was performed using data from Seoul National University Hospital and Samsung Medical Center. Mortality was assessed at 30 days, 180 days, 1 year, and overall follow-up. The model was developed using LASSO logistic regression and evaluated for discrimination and calibration across cohorts.

Conditions

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Mortality Prediction

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Development Cohort

Patients undergoing non-cardiac surgery at Asan Medical Center. This cohort was used to develop the model.

No Intervention: Observational Cohort

Intervention Type OTHER

Participants underwent non-cardiac surgery and were followed retrospectively without any experimental intervention. Data were collected from electronic medical records and national death registry to assess postoperative mortality outcomes.

Validation Cohort 1

Patients undergoing non-cardiac surgery at Seoul National University Hospital. This cohort was used for external validation.

No Intervention: Observational Cohort

Intervention Type OTHER

Participants underwent non-cardiac surgery and were followed retrospectively without any experimental intervention. Data were collected from electronic medical records and national death registry to assess postoperative mortality outcomes.

Validation Cohort 2

Patients undergoing non-cardiac surgery at Samsung Medical Center. This cohort was also used for external validation.

No Intervention: Observational Cohort

Intervention Type OTHER

Participants underwent non-cardiac surgery and were followed retrospectively without any experimental intervention. Data were collected from electronic medical records and national death registry to assess postoperative mortality outcomes.

Interventions

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No Intervention: Observational Cohort

Participants underwent non-cardiac surgery and were followed retrospectively without any experimental intervention. Data were collected from electronic medical records and national death registry to assess postoperative mortality outcomes.

Intervention Type OTHER