Sarcopenia in Patients With Idiopathic Pulmonary Fibrosis

NCT ID: NCT07178197

Last Updated: 2025-09-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-12-01

Study Completion Date

2023-12-31

Brief Summary

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Sarcopenia negatively affects the prognosis of chronic diseases. However, the importance of sarcopenia in patients with idiopathic pulmonary fibrosis (IPF) has been less emphasized. The aim of the study is to determine the prevalence of sarcopenia in patients with IPF and to evaluate the impact of sarcopenia on quality of life and disease progression.

This study was designed as a descriptive cross-sectional. The study included patients diagnosed with IPF. Hand dynamometry and bioelectrical impedance analysis (BIA) were used to for diagnose of sarcopenia. Pulmonary function tests, maximal inspiratory pressure (MIP), and maximal expiratory pressure (MEP) measurements were examined. The 6-minute walk distance (6MWD) and 4-meter walking speed were recorded. The St. George Respiratory Questionnaire (SGRQ) was used to assess quality of life. All patients were evaluated for progressive disease.

Detailed Description

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The study was designed as a cross-sectional study.

Conditions

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Idiopathic Pulmonary Fibrosis (IPF) Sarcopenia

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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idiopathic pulmonary fibrosis (IPF)

The prevalence of sarcopenia was investigated in patients with IPF who met the inclusion and exclusion criteria. The relationship between sarcopenia and quality of life and disease progression in patients with IPF was evaluated.

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Being over 18 years of age
* Signing the informed consent form
* Having a diagnosis of IPF for at least one month

Exclusion Criteria

* Pregnancy
* History of cancer within the last 5 years
* History of lung surgery
* History of neuromuscular disease
* Active pulmonary tuberculosis
* Active respiratory tract infection
* Inability to perform pulmonary function tests
* Presence of a pacemaker
* History of systemic steroid use within the past 3 months
* Inability to use a hand dynamometer
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Mersin University

OTHER

Sponsor Role lead

Responsible Party

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Sibel Naycı

Prof. Dr.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Mersin University Faculty of Medicine

Mersin, Mersin, Turkey (Türkiye)

Site Status

Countries

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Turkey (Türkiye)

Other Identifiers

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2022/736

Identifier Type: -

Identifier Source: org_study_id

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