Prospective Observational Study to Compare REMS vs NEWS2 for Patients Presenting to the ED With Sepsis

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

130 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-01-01

Study Completion Date

2024-12-31

Brief Summary

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Prospective observational study to determine the utility of Rapid Emergency Medicine Score (REMS) in comparison to National Early Warning Score2 (NEWS2) for predicting morbidity and mortality among patients presenting to the Emergency Department with clinical suspicion of Sepsis

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Detailed Description

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Rapid Emergency Medicine Score (REMS) is an attenuated version of the Acute Physiology and Chronic Health Evaluation (APACHE) II score and has utility in predicting mortality in non- surgical patients. The NEWS2 can be used on all hospitalized patients to allow for the early detection of clinical deterioration and potential need for higher level of care. NEWS2 is closely associated with sepsis, however REMS is not so. But in recent studies comparing other EWS (Early Warning Scores) of sepsis, REMS was found to be superior.

Hence comparing REMs against NEWS2 to determine prognostication value of both scores in sepsis.

Conditions

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Sepsis

Study Design

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Observational Model Type

OTHER

Study Time Perspective

PROSPECTIVE

Study Groups

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Sepsis patients

Antibiotics, Vasopressors

Intervention Type DRUG

Both groups are scored on REMS and NEWS2, and then observed closely for the period of hospital stay with regard to ICU stay duration, ventilator days, vasopressor dependent days and total hospital duration

Interventions

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Antibiotics, Vasopressors

Both groups are scored on REMS and NEWS2, and then observed closely for the period of hospital stay with regard to ICU stay duration, ventilator days, vasopressor dependent days and total hospital duration

Intervention Type DRUG

Eligibility Criteria

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Inclusion Criteria

* All patients presenting to ED of Tertiary Care Hospital in Thrissur.
* Patients age \>/=18 years
* Patients who give informed consent for participation in the study.
* Suspicion of sepsis at the time of presentation to ED as per SSC Guidelines 2021

Exclusion Criteria

* All patients with an alternate diagnosis other than sepsis at the time of discharge.
* Patients referred from other hospitals with diagnosis of sepsis, after initiation of treatment

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No