Pontic Shield and Mineralized Plasmatic Matrix for Ridge Preservation

NCT ID: NCT07171879

Last Updated: 2025-09-17

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 56 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2024-09-01
• Study Completion Date: 2025-07-01

Brief Summary

This study is testing new methods to preserve the jawbone and gum tissue after removing a damaged front tooth. Normally, when a tooth is taken out, the bone and gums in that area shrink, which can make future dental treatment more difficult and affect appearance. A technique called Partial Extraction Therapy (Pontic Shield Technique) keeps part of the tooth root in place to help maintain the natural shape of the bone and gums. Another method, called Mineralized Plasmatic Matrix (MPM), uses a patient's own blood mixed with bone particles to support healing.

In this randomized clinical trial, 56 patients were assigned to one of four groups:

Group I: Tooth extraction only Group II: Tooth extraction with MPM grafting Group III: Pontic shield technique alone Group IV: Pontic shield technique with MPM grafting The main outcome measured was the amount of bone width preserved, using 3D X-rays (CBCT). Other outcomes included bone height and soft-tissue healing over 4 months.

This research will help determine whether the pontic shield technique, with or without MPM, provides better preservation of bone and gum tissue compared to tooth extraction alone.

Conditions

Alveolar Ridge Preservation

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: TREATMENT
• Blinding Strategy: SINGLE

Study Groups

Extraction Only

Patients receive total tooth extraction in the esthetic maxillary zone without any adjunctive grafting.

Group Type: ACTIVE_COMPARATOR

Tooth Extraction only

Intervention Type: PROCEDURE

Conventional atraumatic extraction of the non-restorable maxillary tooth in the esthetic zone without socket preservation procedures.

Extraction + MPM

Patients receive total tooth extraction in the esthetic maxillary zone, followed by grafting with MPM.

Group Type: ACTIVE_COMPARATOR

Extraction + MPM

Intervention Type: PROCEDURE

Tooth extraction followed by socket grafting using MPM, prepared from autologous blood combined with xenograft bone particles.

Pontic Shield Only

Patients undergo the pontic shield technique, in which a portion of the buccal root is preserved to maintain ridge contour, without grafting.

Group Type: ACTIVE_COMPARATOR

Pontic Shield Only

Intervention Type: PROCEDURE

Partial extraction therapy using the pontic shield technique, in which the buccal root fragment is preserved to maintain ridge contour, without additional grafting.

Pontic Shield + MPM

Patients undergo the pontic shield technique combined with MPM grafting for ridge preservation.

Group Type: ACTIVE_COMPARATOR

Pontic Shield + MPM

Intervention Type: PROCEDURE

Pontic shield technique combined with grafting using mineralized plasmatic matrix (MPM) for enhanced ridge preservation and healing.

Interventions

Tooth Extraction only

Conventional atraumatic extraction of the non-restorable maxillary tooth in the esthetic zone without socket preservation procedures.

Intervention Type: PROCEDURE

Extraction + MPM

Tooth extraction followed by socket grafting using MPM, prepared from autologous blood combined with xenograft bone particles.

Intervention Type: PROCEDURE

Pontic Shield Only

Partial extraction therapy using the pontic shield technique, in which the buccal root fragment is preserved to maintain ridge contour, without additional grafting.

Intervention Type: PROCEDURE

Pontic Shield + MPM

Pontic shield technique combined with grafting using mineralized plasmatic matrix (MPM) for enhanced ridge preservation and healing.

Intervention Type: PROCEDURE

Eligibility Criteria

Inclusion Criteria

• Adults (≥18 years).
• Classified as ASA I (healthy) according to the American Society of Anesthesiologists Physical Status Classification.
• Presence of Type 1 extraction sockets (intact buccal bone and soft tissues).
• Adequate oral hygiene.
• Sufficient inter-arch space for prosthetic rehabilitation.
• Willingness to comply with study protocol and follow-up schedule.

Exclusion Criteria

• Systemic conditions affecting bone metabolism or wound healing (e.g., uncontrolled diabetes, osteoporosis, immunosuppression).
• History of head and neck radiotherapy or bisphosphonate therapy.
• Acute infection or suppuration at the extraction site.
• Severe periodontal disease.
• Root caries or tooth mobility.
• Buccal bone plate loss due to vertical/horizontal root fractures or advanced periodontitis.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 65 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Soaad Tolba Mohammed Tolba Badawi

OTHER

Sponsor Role: lead

Responsible Party

Soaad Tolba Mohammed Tolba Badawi

Lecturer of Oral and Maxillofacial Surgery, Faculty of Dentistry, Mansoura University

Responsibility Role: SPONSOR_INVESTIGATOR

Principal Investigators

Soaad Tolba Badawy, Lecturer, Oral Surgery, MU

Role: PRINCIPAL_INVESTIGATOR

Mansoura University

Locations

Faculty of Dentistry, Mansoura University

Al Mansurah, Dakahlia Governorate, Egypt

Countries

Egypt

Other Identifiers

R.25.09.22

Identifier Type: -

Identifier Source: org_study_id