Comparing TCAF and MTUN With Soft Tissue Grafting for Treating Single Recessions in the Premandible

NCT ID: NCT07158541

Last Updated: 2025-09-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-08-25

Study Completion Date

2037-12-31

Brief Summary

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Multiple techniques can be used for recession coverage. The most common techniques for single recessions are : tunnel technique (T) and coronally advanced flap (CAF) both combined with a palatal graft to provide sufficient gingival thickness. Recently two modifications have been described in literature, namely the tunneled coronally advanced flap and the modified tunnel. MTUN will function as the control group while people treated with the TCAF technique will function as the test group.

This randomized controlled trial compares MTUN and TCAF to determine which technique provides better root coverage for receding gums at single recession in the premandible. The main question it aims to answer is:

\- What is the average root coverage achieved with each technique in the short and long term? This may be clinically relevant because covering gum recession can reduce tooth sensitivity, improve aesthetics and make oral hygiene easier.

Researchers will compare the modified tunnel technique (MTUN = the gum is undermined) with the tunneled coronally advanced flap (TCAF = the gum is undermined, only partially detached and repositioned higher). In both techniques, a small piece of tissue is removed from the palate, which is used to cover the recession. The purpose of the connective tissue graft under the flap/tunnel, is to increase thickness and provide support. Pain associated to the material used to cover the donorsite will be seen as the secondary research question. The site will either be covered by spongostan and multiple stitches or a palatal stent.

Participants will:

* Undergo surgery (MTUN or TCAF, randomly assigned) to cover recessions
* Attend regular check-ups for up to 10 years after surgery
* Keep a postoperative journal (recording medication use, pain levels, tooth sensitivity, etc.)

Detailed Description

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Conditions

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Gingival Recession, Localized Gingival Recession Localized Moderate Gingival Recession Gingival Recession, Mucogingival Surgery Gingival Recession, Plastic Surgery

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Investigators Outcome Assessors

Study Groups

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TCAF + CTG

Tunneled coronally advanced flap with a connective tissue graft.

Group Type ACTIVE_COMPARATOR

tunneled coronally advanced flap with connective tissue graft

Intervention Type PROCEDURE

The gum at the recession site is undermined, only partially detached and reattached higher (combined withh a connective tissue graft).

MTUN + CTG

Modified tunnel with connective tissue graft.

Group Type ACTIVE_COMPARATOR

modified tunnel with connective tissue graft

Intervention Type PROCEDURE

At the recession site, the gingiva is undermined to create a tunnel, and a connective tissue graft is inserted through the sulcus into this space before advancing the flap coronally.

Interventions

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tunneled coronally advanced flap with connective tissue graft

The gum at the recession site is undermined, only partially detached and reattached higher (combined withh a connective tissue graft).

Intervention Type PROCEDURE

modified tunnel with connective tissue graft

At the recession site, the gingiva is undermined to create a tunnel, and a connective tissue graft is inserted through the sulcus into this space before advancing the flap coronally.

Intervention Type PROCEDURE

Other Intervention Names

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TCAF + CTG MTUN + CTG

Eligibility Criteria

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Inclusion Criteria

* at least 18 years old
* good oral hygiene
* presence of one recession in the premandible
* good general health

Exclusion Criteria

* smoker
* pregnant women (assessed at each visit; if the patient appears pregnant during follow-up, x-rays will not be taken)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University Hospital, Ghent

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Department of Periodontology and Implantology of Ghent University

Ghent, Oost-Vlaanderen, Belgium

Site Status RECRUITING

Countries

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Belgium

Central Contacts

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Véronique Prof. Dr. Christiaens

Role: CONTACT

+32 332 40 17

Facility Contacts

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Véronique Prof. Dr. Christiaens

Role: primary

+32 332 40 17

Other Identifiers

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ONZ-2025-0160

Identifier Type: -

Identifier Source: org_study_id

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