Efficacy of Combining Movement Representation Techniques to Active Neural Mobilization in the Mechanosensitivity of the Median Nerve in Asymptomatic Volunteers.

NCT ID: NCT07154017

Last Updated: 2025-09-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

NOT_YET_RECRUITING

Clinical Phase

NA

Total Enrollment

10 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-09-30

Study Completion Date

2025-12-31

Brief Summary

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The objective of this study will be to determine whether the combination of movement imaging techniques with neural mobilization (NM) exercises works to modify median nerve sensitivity to mechanical stimuli. Movement Representation Techniques (MRTs) are defined as therapeutic or training systems that neurophysiologically evoke a perceptual-cognitive representation of movement. They can be combined with the execution of actual movement or with afferent sensory stimulation (motor command). There is evidence demonstrating positive results in pain reduction and improved range of motion using MRTs alone.

The study will be evaluated in 10 randomly selected asymptomatic volunteers, considering the following variables: pressure pain threshold, elbow extensor range of motion, and sensory responses before and after the intervention, in both the experimental and control groups. The period between interventions will be 72 hours.

Detailed Description

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The objective of this pilot study will be to determine the efficacy of combining movement representation techniques with neural mobilization (NM) exercises on median nerve mechanosensitivity. Movement representation techniques (MRTs) are defined as therapeutic or training systems that neurophysiologically evoke a perceptual-cognitive representation of movement through imagery or observation of motor actions. They can be combined with actual movement execution or with afferent sensory stimulation (motor command). There is evidence demonstrating positive results in pain reduction and range of motion gains using MRTs alone.

The study will be designed as a randomized, single-blind, crossover pilot clinical trial. In this study, 10 asymptomatic volunteers will be randomly selected and measured in the following variables: pressure pain threshold (PPT), elbow extensor range of motion (EROM), and the spatiotemporal distribution of pre- and post-intervention sensory responses in both the experimental group (RMM + MN) and the control group (MN). The washout period between interventions will be 72 hours.

Conditions

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Median Nerve

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

A Pilot Study, Single-blind,Randomized, Crossover.
Primary Study Purpose

OTHER

Blinding Strategy

DOUBLE

Investigators Outcome Assessors
Evaluators

Study Groups

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Combination of Movement Representation Techniques with Neural Mobilization Exercises (experimental)

Combination of Movement Representation Techniques (Action observation, Motor imagery and Mirror therapy) with Neural Mobilization Exercises (Active neural mobilization of Median nerve)

Group Type EXPERIMENTAL

Combination of Movement Representation Techniques with neural mobilization exercises

Intervention Type OTHER

The experimental intervention will be an exposition of movement representation techniques in an established sequential order, consisting of action observation, implicit/explicit motor imagery and visual feedback with a mirror in combination with neural mobilization exercises.

Neural Mobilization Excercises (control)

Neural Mobilization Exercises (Active neural mobilization of Median nerve)

Group Type ACTIVE_COMPARATOR

Neural mobilization exercises

Intervention Type OTHER

The control intervention will consist in three series of active neural mobilization exercises

Interventions

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Combination of Movement Representation Techniques with neural mobilization exercises

The experimental intervention will be an exposition of movement representation techniques in an established sequential order, consisting of action observation, implicit/explicit motor imagery and visual feedback with a mirror in combination with neural mobilization exercises.

Intervention Type OTHER

Neural mobilization exercises

The control intervention will consist in three series of active neural mobilization exercises

Intervention Type OTHER

Other Intervention Names

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Neurodinamics excercises

Eligibility Criteria

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Inclusion Criteria

* asymptomatic volunteers of both sexes
* aged 18 to 45
* with no symptoms or history of disease in the cervical region, shoulder girdle, or upper limb.

Exclusion Criteria

* history of surgery or trauma to the cervical spine, shoulder girdle, or upper limb;
* nonspecific shoulder pain;
* presenting symptoms of chronic pain in any region of the body;
* aphantasia (inability to create mental images);
* hypermobility;
* history of cancer or active disease;
* current infection;
* rheumatological disease;
* neurological and/or psychiatric disorders;
* altered sensation;
* current pregnancy;
* consumption of centrally acting medications;
* undergoing physiotherapy treatment in the last month;
* inability to understand the informed consent document;
* previous experience with median nerve provocation testing.
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Gran Rosario

OTHER

Sponsor Role lead

Responsible Party

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Maximiliano Venosta

Physioterapist

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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University of Gran Rosario

Rosario, Santa Fe Province, Argentina

Site Status

Countries

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Argentina

Central Contacts

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Maximiliano Venosta, Physiotherapist

Role: CONTACT

+5493412114064

Mauro S Barone, Doctor-Physiotherapist

Role: CONTACT

+5493412123037

Facility Contacts

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Leonardo Intelangelo, Doctor-Physiotherapist

Role: primary

+5493416758135

Mauro S Barone, Doctor-Physiotherapist

Role: backup

+5493412123037

References

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Matesanz-Garcia L, Caceres-Pajuelo JE, Cuenca-Martinez F, La Touche R, Goicoechea-Garcia C, Fernandez-Carnero J. Effects of neural mobilizations through movement representation techniques for the improvement of neural mechanosensitivity of the median nerve region: a randomized controlled trial. Somatosens Mot Res. 2021 Dec;38(4):267-276. doi: 10.1080/08990220.2021.1964463. Epub 2021 Aug 17.

Reference Type RESULT
PMID: 34404324 (View on PubMed)

Other Identifiers

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886/2024

Identifier Type: -

Identifier Source: org_study_id

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