Innovative Hand Rehabilitation System With Synchronized Contralateral Haptic Feedback
NCT ID: NCT07077460
Last Updated: 2025-08-29
Study Results
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Basic Information
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RECRUITING
NA
100 participants
INTERVENTIONAL
2024-10-04
2025-10-22
Brief Summary
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Currently, hand function training primarily focuses on range of motion, strength, and hand function, although there is comparatively less emphasis on enhancing both force control and brain function. Moreover, studies related to mirror therapy has primarily focused on the execution of functional movements, but has not explored whether hand strength control training can achieve the same training effects on the affected or non-dominant side through the concept of mirror therapy. Furthermore, the effects of combining a hand strength control system with a synchronous contralateral clip-on force feedback device on brain activation and hand function have not yet been studied. Therefore, this study aimed to investigate the effects of integration a finger force control training system with synchronous contralateral force feedback and mirror visual feedback device on brain activation and hand function, aiming to develop a clinically applicable hand rehabilitation system. Additionally, visual feedback from force control training in our study is through the hints displayed virtually on the game interface of the tablet, which were represented as the height of the targets, not as typical as actual movement-based mirror therapy or task-based mirror therapy.
Therefore, the purpose of the study is to understand the differences among training effects of integrating Graded-Pressure Haptic Device-TiPR closed-loop system and MVF; MVF and force control training, as well as isolated force control training, and to explore the training effects on hand strength, hand function and brain activation.
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
SINGLE
Study Groups
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Mirror Visual Feedback Group
All the subjects were asked to use their dominant hands to operate the hand training system (TIPr) and place their non-dominant hands behind the mirror on the other hand training system (TIPr). According to the game instructions shown on the tablet screen, they should slowly press the evaluation system with the corresponding fingers to reach the target force value. When the dominant hand started to cooperate with the game instructions, the force exerted by the fingertips will be presented on the tablet, and the mirror would show the mirrored (reflected) image of force output level. The subjects were instructed to keep their eyes contacts on the reflected image from the mirror and simultaneously "imagine" that the non-dominant hand performing the same task as the dominant hand. Subjects was instructed not to move their non-dominant hand voluntarily.
TIPr
TIPr is a second-generation device, which is originated from Pressing Evaluation and Training System (PETs), developed by NCKU Motion Analysis Lab. This 2nd generation device is a home-based training device, which equipped with single-axis force sensors and displayed visual feedback through a tablet advantages.
Mirror Visual Feedback Device
A box with two compartments through a partition with two mirrors installed on each side, which is applied in Mirror therapy.
Non-Mirror Visual Feedback Group
All the subjects were asked to use their dominant hands to operate the hand training system (TIPr) and place their non-dominant hands behind the mirror on the other hand training system. According to the game instructions shown on the tablet screen, they should slowly press the evaluation system with the corresponding fingers to reach the target force value. When the dominant hand starts to cooperate with the game instructions, the force exerted by the fingertips will be presented on the tablet. Different from MVF group, the mirror would be covered. The subjects were instructed to keep their eyes contact on the tablet and imagine the non-dominant hand performing the same task as the dominant hand without mirror visual feedback. Subjects was instructed not to move their non-dominant hand voluntarily.
TIPr
TIPr is a second-generation device, which is originated from Pressing Evaluation and Training System (PETs), developed by NCKU Motion Analysis Lab. This 2nd generation device is a home-based training device, which equipped with single-axis force sensors and displayed visual feedback through a tablet advantages.
Mirror Visual Feedback Device(Blocked mirror)
Different from Mirror Visual Feedback Device in MVF group, the mirror was blocked by black curtain or paperboard.
Output-Dependent Cutaneous Pressure Tactile plus Mirror Visual Feedback Group
All the subjects were asked to use their dominant hands to operate the hand training system (TIPr) and place their non-dominant hands behind the mirror on the other hand training system (TIPr). Moreover, graded cutaneous pressure feedback, delivered via a novel Graded-Pressure Haptic Device would be applied on non-dominant fingers. When the dominant hand started to play the game, the force exerted by the fingertips will be presented on the tablet, and the mirror would show the mirrored image of force output level. Subjects were instructed to keep their eyes contacts on the mirrored-image and simultaneously "imagine" that the non-dominant hand performing the same task as the dominant hand. At the same time, subjects would additionally received force pulses on the non-dominant fingertip in synchrony with the TiPR game's force output (matched amplitude) to add tactile feedback. Subjects was instructed not to move their non-dominant hand voluntarily.
TIPr
TIPr is a second-generation device, which is originated from Pressing Evaluation and Training System (PETs), developed by NCKU Motion Analysis Lab. This 2nd generation device is a home-based training device, which equipped with single-axis force sensors and displayed visual feedback through a tablet advantages.
Mirror Visual Feedback Device
A box with two compartments through a partition with two mirrors installed on each side, which is applied in Mirror therapy.
Graded-Pressure Haptic Device (Passive press-feedback cushion)
A passive press-feedback cushion (Graded-Pressure Haptic Device) would deliver force pulses to the subjects' non-dominant fingertips in synchrony with the TiPR game's force output (matched amplitude)
Interventions
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TIPr
TIPr is a second-generation device, which is originated from Pressing Evaluation and Training System (PETs), developed by NCKU Motion Analysis Lab. This 2nd generation device is a home-based training device, which equipped with single-axis force sensors and displayed visual feedback through a tablet advantages.
Mirror Visual Feedback Device
A box with two compartments through a partition with two mirrors installed on each side, which is applied in Mirror therapy.
Mirror Visual Feedback Device(Blocked mirror)
Different from Mirror Visual Feedback Device in MVF group, the mirror was blocked by black curtain or paperboard.
Graded-Pressure Haptic Device (Passive press-feedback cushion)
A passive press-feedback cushion (Graded-Pressure Haptic Device) would deliver force pulses to the subjects' non-dominant fingertips in synchrony with the TiPR game's force output (matched amplitude)
Eligibility Criteria
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Inclusion Criteria
* Without past medical history of musculoskeletal or neurological disorders that would affect muscle control ability or cause sensory abnormalities
* Normal cognitive function to understand and follow the instructions
* Able to understand Chinese, English, or Taiwanese language
Exclusion Criteria
* With a history of neuromuscular diseases or degenerative arthritis
* With a history of brain injury
* With a history of taking psychiatric medications
* Unable to understand instructions, or have cognitive impairments
* With a history of physical disabilities (Loss of body parts) or taking relevant medications, including heart disease, peripheral arterial disease, respiratory system diseases, dialysis, unresolved upper extremity injury, or highly addicted to smoking or alcohol
60 Years
80 Years
ALL
Yes
Sponsors
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National Cheng-Kung University Hospital
OTHER
Responsible Party
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Fong Chin Su
Chair Professor
Principal Investigators
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Fong-Chin Su, PHD
Role: PRINCIPAL_INVESTIGATOR
Chair Professor
Locations
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National Cheng Kung University
Tainan City, Taiwan, Taiwan
Countries
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Central Contacts
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Facility Contacts
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References
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Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
113-162
Identifier Type: -
Identifier Source: org_study_id
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