Safety and Effectiveness of A Novel Continuous Glucose and Ketone Monitoring System

NCT ID: NCT07139808

Last Updated: 2025-08-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

12 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-08-01

Study Completion Date

2025-12-01

Brief Summary

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The study is to evaluate the accuracy and safety of a novel real-time continuous glucose and ketone monitoring system among adult patients with type 1 diabetes mellitus (T1DM) with respect to Yellow Spring Instrument (YSI) and Randox reference venous plasma sample measurements.

Detailed Description

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The study is to evaluate the accuracy and safety of a novel real-time continuous glucose and ketone monitoring (CGKM) system among adult patients with type 1 diabetes mellitus with respect to YSI and Randox reference venous plasma sample measurements. Up to 14 patients will be enrolled. Interstitial glucose and ketone readings from the sensors will be obtained immediatedly following each venous blood sample test. Each participant will make 3 visits to the clinical study site, including the screening visit.

Conditions

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Type1diabetes

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

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Adult patients with T1DM

Adult patients with T1DM

Group Type EXPERIMENTAL

GK5 CGKM

Intervention Type DEVICE

Wear for a consecutive 15 days

Interventions

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GK5 CGKM

Wear for a consecutive 15 days

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Age ≥ 18 years
* Diagonsed with T1DM on Continuous subcutaneous insulin infusion (CSII)
* Venous blood sampling access can be established in the forearm
* Capable of independently reading instructions and complying with the clinical trial requirements
* Willing to sign the Informed Consent Form (ICF)

Exclusion Criteria

* Severe hypoglycemia within the past 6 months
* A diagnosed history of Diabetic ketoacidosis (DKA) in the past 3 months
* Heart failure or hemiplegic sequelae due to prior cerebrovascular disease
* Severe skin conditions at the sensor wear site
* Extensive systemic skin disorders
* Having difficulty with wound healing, bleeding disorders, and/or taking anticoagulant medications
* Anemia or abnormal hematocrit
* Blood donation within the past 6 months
* Pregnancy (defined as positive urine test in women ≤55 years), lactation, or plans for pregnancy within ≤30 days
* Current or recent (≤1 month) participation in other clinical trials
* Planned MRI/CT scans during sensor wear
* Allergy to medical adhesives or alcohol
* Conditions impairing comprehension of informed consent or study procedures
* Other exclusionary conditions per investigator's discretion
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Henan University of Science and Technology

OTHER

Sponsor Role lead

Responsible Party

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Peng Liu

Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Hongwei Jiang

Role: PRINCIPAL_INVESTIGATOR

Henan University of Science and Technology

Locations

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Henan University of Science and Technology

Luoyang, Henan, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Peng Liu

Role: CONTACT

0379-64811993

Facility Contacts

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Peng Liu

Role: primary

Other Identifiers

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SS-KY-CGM-0004

Identifier Type: -

Identifier Source: org_study_id

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