A Study of the Continuous Glucose Monitoring System for Home Use in Patients With Diabetes

NCT ID: NCT04964752

Last Updated: 2021-07-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

144 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-07-30

Study Completion Date

2022-04-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Subjects in the upper arm group will have a sensor of the CGM System inserted on each arm (left and right upper arm). Subjects in the abdomen group will have 2 sensors inserted, one on each side of the abdomen (left and right abdomen) The sensors will be placed for 29 days. After sensor insertion, the CGM system should be calibrated with capillary blood glucose readings from a self-monitoring blood glucose meter。

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Diabetes

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

OTHER

Blinding Strategy

NONE

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

the upper arm group on Day 2

The upper arm group to perform Visit 3 venous blood glucose measurement on Day 2.

Group Type OTHER

continuous glucose-monitoring

Intervention Type DEVICE

Continuous glucose-monitoring device indicated for continually recording interstitial fluid glucose levels in patients with diabetes.

the upper arm group on Day 15±1 day

The upper arm group to perform Visit 3 venous blood glucose measurement on Day 15±1 day.

Group Type OTHER

continuous glucose-monitoring

Intervention Type DEVICE

Continuous glucose-monitoring device indicated for continually recording interstitial fluid glucose levels in patients with diabetes.

the upper arm group on Day 29±1 day

The upper arm group to perform Visit 3 venous blood glucose measurement on Day 29±1 day.

Group Type OTHER

continuous glucose-monitoring

Intervention Type DEVICE

Continuous glucose-monitoring device indicated for continually recording interstitial fluid glucose levels in patients with diabetes.

the abdomen group on Day 2

The abdomen group to perform Visit 3 venous blood glucose measurement on Day 2.

Group Type OTHER

continuous glucose-monitoring

Intervention Type DEVICE

Continuous glucose-monitoring device indicated for continually recording interstitial fluid glucose levels in patients with diabetes.

the abdomen group on Day 15±1

The abdomen group to perform Visit 3 venous blood glucose measurement on Day 15±1.

Group Type OTHER

continuous glucose-monitoring

Intervention Type DEVICE

Continuous glucose-monitoring device indicated for continually recording interstitial fluid glucose levels in patients with diabetes.

the abdomen group on Day 29±1

The abdomen group to perform Visit 3 venous blood glucose measurement on Day 29±1.

Group Type OTHER

continuous glucose-monitoring

Intervention Type DEVICE

Continuous glucose-monitoring device indicated for continually recording interstitial fluid glucose levels in patients with diabetes.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

continuous glucose-monitoring

Continuous glucose-monitoring device indicated for continually recording interstitial fluid glucose levels in patients with diabetes.

Intervention Type DEVICE

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

CGM

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

1. Type 1 or 2 diabetes mellitus
2. Male or female age ≥ 18 years old and ≤ 70 years old
3. Willingness to adopt measures to prevent water coming into contact with the device sensor (e.g. abstain from swimming, sauna, avoid hitting the sensor with direct jets of water)
4. Ability to communicate with the investigators, able to operate medical device after training and comply with the testing procedures outlined in this protocol (including, but not limited to, willing to wear the continuous glucose monitor and testing capillary blood glucose)
5. Subjects who show understanding of the study procedures and willing to sign a written informed consent form.

Exclusion Criteria

1. Hospitalization due to diabetic ketoacidosis or severe hypoglycemia, within 3 months prior to screening
2. HbA1c \>13% or urine ketone 3+
3. Use of pacemaker
4. Body Mass Index (BMI) ≤18.0kg/m2
5. Extensive skin changes/diseases that preclude wearing the required number of devices on normal skin at the proposed application sites, i.e. upper arm or abdomen (e.g., extensive psoriasis, recent burns or severe sunburn, extensive eczema, extensive scarring, extensive tattoos, dermatitis herpetiformis)
6. Any psychiatric disease such as depression or anxiety
7. Any severe hepatic, renal, cardiac, cerebral, respiratory or neurological diseases (e.g. serum ALT, AST, Creatinine level ≥3 times the upper limit of normal)
8. Has a MRI scan, CT scan or other procedure requiring the subject be under strong magnetic or electromagnetic environment, scheduled during the proposed study participation
9. Blood loss \>400ml in the past 3 months (including blood donation)
10. Have a known allergy to medical-grade adhesives, or known hypersensitivity to any of the products used in the study
11. Difficulty in sampling venous blood or cannot tolerate venipuncture
12. Participated in other investigational studies in the past 3 months
13. Currently pregnant or lactating women, or positive pregnancy test
14. Any condition that, in the opinion of the investigator, renders the subject not suitable for the study.
Minimum Eligible Age

18 Years

Maximum Eligible Age

70 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Powder (Guangzhou) Pharmaceuticals Limited

UNKNOWN

Sponsor Role collaborator

Powder Pharmaceuticals (HK) Co., Ltd

UNKNOWN

Sponsor Role collaborator

Lee's Pharmaceutical Limited

INDUSTRY

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Elaine Chow, Prof.

Role: PRINCIPAL_INVESTIGATOR

Prince of Wales Hospital, the Chinese University of Hong Kong

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Elaine Chow, Prof.

Role: CONTACT

(852) 3505 1642

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

PL-CGM-202006

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.