Continuous Glucose Monitoring System Use in Pediatric Patients with Diabetes

NCT ID: NCT06570551

Last Updated: 2024-09-26

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

78 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-03-30

Study Completion Date

2024-08-21

Brief Summary

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To verify and evaluate the efficacy and safety of i3 CGM system manufactured by Changsha Sinocare Inc. for continuous or regular monitoring of interstitial fluid glucose level in pediatric patients with diabetes.

Detailed Description

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This clinical investigation is of a multi-center and self-controlled design.

This clinical investigation is planned to be conducted in 3 study sites, with a total of 78 subjects to be enrolled, of which no fewer than 15 cases are aged 2-5 years old, and no fewer than 60 cases are aged 6-17 years old. This clinical investigation is to verify the safety and efficacy of the investigational device. Referring to the number of pediatric patients with diabetes in the 3 study sites, it is expected that about 20 subjects will be enrolled in each site every month, and it will take about 2 months to close the site. This clinical investigation is expected to be completed in about 6 months from the first participant recruited.

The real-time glucose values measured by CGM system on the left and right abdomen are compared with the venous blood glucose value (EKF value) measured by EKF analyzer, respectively, and the consistency rate is analyzed.

Conditions

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Diabetes Mellitus

Study Design

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Observational Model Type

OTHER

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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2-5 year old participants

Wear the investigational device continuously for 15 days.

i3 CGM(continuous glucose monitor)

Intervention Type DEVICE

The i3 CGM consists of a Sensor Pack (including probe, iCGM-S3), a Transmitter Pack (iCGM-t3), and an application (iCGM-APP (released version: V02)).application (i3 CGM App). The user can view their glucose data on the i3 CGM App running on a compatible mobile device.

6-17 year old participants

Wear the investigational device continuously for 15 days.

i3 CGM(continuous glucose monitor)

Intervention Type DEVICE

The i3 CGM consists of a Sensor Pack (including probe, iCGM-S3), a Transmitter Pack (iCGM-t3), and an application (iCGM-APP (released version: V02)).application (i3 CGM App). The user can view their glucose data on the i3 CGM App running on a compatible mobile device.

Interventions

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i3 CGM(continuous glucose monitor)

The i3 CGM consists of a Sensor Pack (including probe, iCGM-S3), a Transmitter Pack (iCGM-t3), and an application (iCGM-APP (released version: V02)).application (i3 CGM App). The user can view their glucose data on the i3 CGM App running on a compatible mobile device.

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Aged 2 (inclusive) - 18 years (exclusive);
* Clinically diagnosed with diabetes;
* Being willing to wear the device continuously for 15 days and conduct blood collection for blood glucose testing in accordance with the requirements of this protocol;
* Body weight not less than 10.0 kg;
* Consent to participate in this clinical investigation, and sign the Informed Consent Form (ICF).

Exclusion Criteria

* Need to undergo magnetic resonance imaging (MRI) during the clinical investigation;
* Diffuse subcutaneous nodules;
* Acute complications of diabetes;
* Abnormal coagulation function (coagulation cannot be too quick or too slow); the criteria for judging abnormalities are: The activated partial thromboplastin time (APTT) is higher than 1.5 times the upper limit of normal value or lower than the lower limit of normal value; or The prothrombin time (PT) is higher than 1.5 times the upper limit of normal value or lower than the lower limit of normal value
* Participation in other clinical investigations within the past 1 month;
* Where the investigator does not consider the patient suitable for enrollment.
Minimum Eligible Age

2 Years

Maximum Eligible Age

17 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Sinocare

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Hunan Children's Hospital

Changsha, Hunan, China

Site Status

Children's Hospital of Soochow University

Suzhou, Jiangsu, China

Site Status

Women and Children's Hospital of Ningbo University

Ningbo, Zhejiang, China

Site Status

Countries

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China

Other Identifiers

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NPI031-CIP-005

Identifier Type: -

Identifier Source: org_study_id

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