5 Year Follow up of SMILE® Procedure for the Correction of Hyperopia

NCT ID: NCT07133737

Last Updated: 2025-08-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-01-01

Study Completion Date

2025-12-31

Brief Summary

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The planned study will investigate and evaluate refractive stability, predictability, and safety in patients who underwent SMILE® pro surgery for hyperopia with or without astigmatism at least five years ago.

This study aims to gain long-term insights into the predictability, safety, stability and side effects of the SMILE® pro procedure. It will evaluate the refractive outcome so the findings can optimize treatment nomograms and selection criteria while providing evidence of the long-term stability and predictability of the procedure.

Approximately 100 patients in the Czech Republic and Germany will participate in this study. The study was reviewed and approved by an independent research ethics committee.The study will consist of a single visit, where standard, non-invasive and painless examinations will be performed. The course of this visit will correspond to the patient's last visit five years ago as part of the clinical trial

Detailed Description

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Conditions

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Hyperopia

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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post hyperopia correction

Patients who underwent hyperopia correction surgery using Femtosecond laser system VisuMax with treatment option ReLEx SMILE at least 5 years ago and were part of the original clinical investigation

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* Patients who underwent the SMILE hyperopic procedure as part of the study referenced PHOBOS.
* Patients should be able to understand the patient information and willing to sign an informed consent.
* Patients should be willing to comply with all examinations during the visit.

Exclusion Criteria

* Patients with severe ocular or generic disorders that would prevent them from completed the visit.
* Patients not being able to understand and give informed consent.
* Patients who did not underwent the SMILE hyperopic procedure as part of the study referenced PHOBOS.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Gemini Eye Clinic

INDUSTRY

Sponsor Role lead

Responsible Party

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Dr. Pavel Stodulka

Principal Investigator

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Pavel Stodulka, Dr. Ph.D, FEBOS-CR

Role: PRINCIPAL_INVESTIGATOR

Gemini Eye Clinic

Anke Messerschmidt-Roth, Dr. rer. medic.

Role: PRINCIPAL_INVESTIGATOR

Klinik für Augenheilkunde Marburg

Walter Sekundo, Prof. Dr. med.

Role: PRINCIPAL_INVESTIGATOR

Klinik für Augenheilkunde Marburg

Locations

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Gemini Eye Clinic

Zlín, , Czechia

Site Status

Universitätsklinikum Marburg - Klinik für Augenheilkunde

Marburg, , Germany

Site Status

Countries

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Czechia Germany

References

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Waring GO 3rd, Reinstein DZ, Dupps WJ Jr, Kohnen T, Mamalis N, Rosen ES, Koch DD, Obstbaum SA, Stulting RD. Standardized graphs and terms for refractive surgery results. J Refract Surg. 2011 Jan;27(1):7-9. doi: 10.3928/1081597X-20101116-01. No abstract available.

Reference Type BACKGROUND
PMID: 21229953 (View on PubMed)

Related Links

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Other Identifiers

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PHOBOS-5FU

Identifier Type: -

Identifier Source: org_study_id

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