A Continuation Study To Monitor The Long Term Safety Of Patients Completing Protocols ACU-P08-020/020A

NCT ID: NCT01895088

Last Updated: 2017-08-01

Study Results

Results available

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Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

271 participants

Study Classification

INTERVENTIONAL

Study Start Date

2011-05-31

Study Completion Date

2015-08-31

Brief Summary

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This is a 2 year follow up study to monitor the long term safety of the ACI 7000PDT in subjects who are still implanted with the ACI and have successfully completed the ACU-P08-020/020A studies.

Detailed Description

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This is a two year follow up study designed to monitor and obtain long-term safety data of the ACI 7000PDT in subjects who participated and successfully completed the ACU-P08-020/020A studies. Subjects must be able to provide voluntary informed consent, and must sign and be given a copy of the written Informed Consent form prior to participating. This continuation study follows subjects still implanted with the ACI and includes two visits, at 12-month intervals, after subjects have been exited (at Month 36) from the ACU-P08-020/020A studies. The first visit is at Month 48 following implantation followed by a final Month 60 visit. The study parameters being measured at these two visits include:

* Specular microscopy
* Slit lamp and fundus examination (ocular health)
* Corrected and uncorrected visual acuity
* Manifest mid-point refraction
* Corneal topography
* Dry eye assessment
* Mesopic and Photopic contrast sensitivity
* Adverse events and complications

All sites participating in the ACU-P08-020/020A studies were invited to participate in the continuation study.

Conditions

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Presbyopia

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Patients prev. impl. with ACI 7000 PDT

AcuFocus Corneal Inlay ACI 7000 PDT

Group Type EXPERIMENTAL

AcuFocus Corneal Inlay ACI 7000 PDT

Intervention Type DEVICE

Inlay implanted in cornea for improvement of near vision

Interventions

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AcuFocus Corneal Inlay ACI 7000 PDT

Inlay implanted in cornea for improvement of near vision

Intervention Type DEVICE

Other Intervention Names

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AcuFocus KAMRA inlay

Eligibility Criteria

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Inclusion Criteria

* Patients must have completed participation in the ACU-P08-020/020A clinical trial.
* Patients must be able to provide voluntary informed consent, and must sign and be given a copy of the written Informed Consent form.

Exclusion Criteria

* Patients who did not complete ACU-P08-020/020A.
Minimum Eligible Age

45 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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AcuFocus, Inc.

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Daniel Durrie, M.D.

Role: PRINCIPAL_INVESTIGATOR

Durrie Vision

Chad Betts, M.D., R.Ph

Role: PRINCIPAL_INVESTIGATOR

MacDonald Eye Associates

Vance Thompson, M.D.

Role: PRINCIPAL_INVESTIGATOR

Vance Thompson Vision

Jay Pepose, M.D.

Role: PRINCIPAL_INVESTIGATOR

Pepose Vision Institute

Kevin Waltz, M.D.

Role: PRINCIPAL_INVESTIGATOR

Eye Surgeons of Indiana

John Vukich, M.D.

Role: PRINCIPAL_INVESTIGATOR

Davis Duehr Dean

Peter Hersh, M.D.

Role: PRINCIPAL_INVESTIGATOR

Cornea and Laser Eye Institute

Thomas Tooma, M.D.

Role: PRINCIPAL_INVESTIGATOR

NVision

Colman Kraff, M.D.

Role: PRINCIPAL_INVESTIGATOR

Kraff Eye Institute

Robert Maloney, M.D.

Role: PRINCIPAL_INVESTIGATOR

Maloney Vision Institute

Scott MacRae, M.D.

Role: PRINCIPAL_INVESTIGATOR

University of Rochester Eye Institute - Strong Vision

Gary Foster, M.D.

Role: PRINCIPAL_INVESTIGATOR

Eye Center of Northern Colorado

Phillip Hoopes, Sr., M.D.

Role: PRINCIPAL_INVESTIGATOR

Hoopes Vision

Locations

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McDonald Eye Associates

Fayetteville, Arkansas, United States

Site Status

Maloney Vision

Los Angeles, California, United States

Site Status

NVision

Newport Beach, California, United States

Site Status

Eye Center NOCO

Fort Collins, Colorado, United States

Site Status

Kraff Eye Institute

Chicago, Illinois, United States

Site Status

Eye Surgeons of Indiana

Indianapolis, Indiana, United States

Site Status

Durrie Vision

Overland Park, Kansas, United States

Site Status

Pepose Vision Institute

Chesterfield, Missouri, United States

Site Status

The Cornea & Laser Eye Institute, P.A

Teaneck, New Jersey, United States

Site Status

University of Rochester Eye Institute - Strong Vision

Rochester, New York, United States

Site Status

Vance Thompson Vision

Sioux Falls, South Dakota, United States

Site Status

Hoopes Vision

Sandy City, Utah, United States

Site Status

Davis Duehr Dean

Madison, Wisconsin, United States

Site Status

Countries

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United States

Related Links

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Other Identifiers

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ACU-P12-020C

Identifier Type: -

Identifier Source: org_study_id

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